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Therapy: Hormonal Therapy

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Total 218 results found since Jan 2013.

Many Women Unaware of Female-Specific Stroke Symptoms
Pregnancy, migraines and hormone therapy put women at increased risk, researchers say Source: HealthDay Related MedlinePlus Pages: Stroke, Women's Health
Source: MedlinePlus Health News - May 7, 2015 Category: Consumer Health News Source Type: news

Menopausal Hormone Therapy for the prevention of cardiovascular disease: Evidence-based customization
Boardman et al. provided this March an updated version of their 2013 Cochrane review [1], aiming to assess the effects of menopausal hormone therapy (MHT) for the prevention of cardiovascular disease in postmenopausal women. The authors concluded that treatment with MHT in postmenopausal women, for either primary or secondary prevention of cardiovascular disease, has little, if any, benefit and causes an increase in the risk of stroke and venous thromboembolic events.
Source: Maturitas - May 7, 2015 Category: Primary Care Authors: Dimitrios G. Goulis, Irene Lambrinoudaki Tags: Editorial Source Type: research

Hormone therapy and venous thromboembolism among postmenopausal women
Despite a decrease in postmenopausal hormone therapy (HT) use during the last decade, many women are still prescribed this treatment which remains the most effective to counteract climacteric symptoms. However, HT increases the risk of breast cancer, stroke and venous thromboembolism (VTE) which represents the major harmful effect of short-term duration use. Nevertheless, this benefit/risk ratio has been established among women using oral estrogens alone or combined with a specific progestogen and cannot be necessary extrapolated to other HT.
Source: Maturitas - April 21, 2015 Category: Primary Care Authors: Marianne Canonico Tags: INV32 Source Type: research

Menopausal hormone therapy, depression, headache, vasomotor symptoms and absence from work: results from 3 years follow up in a Dutch gynecology clinic
Introduction: Use of menopausal hormone therapy (MHT) has dropped worldwide during the last decade after the ‘Women's Health Initiative’ (WHI) trial reported increased breast cancer, stroke and embolism risk. Women with bothersome menopausal complaints resorted to complementary and alternative medications with less or unproven efficacy. Even when indicated use of MHT is low and of short duration, possibly affecting individual wellbeing and ability to work.
Source: Maturitas - April 21, 2015 Category: Primary Care Authors: Mojdeh Shayesteh, Ingrid Pinas Tags: O5 Source Type: research

Associations between postmenopausal hormone therapy and strokes in a National cohort study
The Women Health Initiative randomized clinical studies on effects of two postmenopausal hormone therapies (HT) were stopped prematurely mainly due to stroke risk.
Source: Maturitas - April 21, 2015 Category: Primary Care Authors: Ellen Løkkegaard, Anne K. Nielsen, Øjvind Lidegaard Tags: O28 Source Type: research

Menopausal hormone therapy use in 17 European countries during the last decade
Introduction: The first ‘Women's Health Initiative’ (WHI) randomised controlled trial assessed use of continuous combined menopausal hormone therapy (cc-MHT). It was prematurely stopped because of an increased invasive breast cancer (BC), coronary heart disease (CHD), stroke and pulmonary embolism risk. Consequently, scientific societies recommended use of MHT at the lowest effective dose for the shortest duration. As a result, a sharp decline in MHT use occurred worldwide.
Source: Maturitas - April 21, 2015 Category: Primary Care Authors: Lieveke Ameye, Caroline Antoine, Marianne Paesmans, Evandro de Azambuja, Serge Rozenberg Tags: O44 Source Type: research

The risk of fatal stroke in Finnish postmenopausal hormone therapy users before and after the Women's Health Initiative: A cohort study
Stroke is the third most common cause of death and the most common cause of prolonged disability in women worldwide[1]. Therefore, the American Heart and Stroke Association recently published strict new guidelines for the prevention of stroke in women [2]. These guidelines acknowledge a number of female gender-related risk factors for stroke, such as migraine, pregnancy, pre-eclampsia, atrial fibrillation, obesity, metabolic syndrome, living alone -status and consequent delay in thrombolysis, and longevity.
Source: Maturitas - April 13, 2015 Category: Primary Care Authors: Pauliina Tuomikoski, Heli Lyytinen, Pasi Korhonen, Fabian Hoti, Pia Vattulainen, Mika Gissler, Olavi Ylikorkala, Tomi S. Mikkola Source Type: research

Bioidentical hormones, menopausal women, and the lure of the “natural” in U.S. anti-aging medicine
Publication date: May 2015 Source:Social Science & Medicine, Volume 132 Author(s): Jennifer R. Fishman , Michael A. Flatt , Richard A. Settersten Jr. In 2002, the Women's Health Initiative, a large-scale study of the safety of hormone replacement therapy (HRT) for women conducted in the United States, released results suggesting that use of postmenopausal HRT increased women's risks of stroke and breast cancer. In the years that followed, as rates of HRT prescription fell, another hormonal therapy rose in its wake: bioidentical hormone replacement therapy (BHRT). Anti-aging clinicians, the primary prescribers of ...
Source: Social Science and Medicine - March 19, 2015 Category: Psychiatry & Psychology Source Type: research

More Evidence That Hormone Therapy Might Not Help Women's Hearts
Review also found raised risk of stroke for some, although timing of use may be a key factor
Source: Cancercompass News: Breast Cancer - March 12, 2015 Category: Cancer & Oncology Source Type: news

HRT review finds increased risk of blood clots and stroke
Conclusion This updated Cochrane review has found that oral HRT increases risk of stroke and blood clots, and does not appear to reduce overall risk of cardiovascular disease or death during follow-up. More exploratory analyses suggested that HRT might reduce risk of death from heart disease or non-fatal heart attack if it was started within 10 years of menopause, but this finding needs further confirmation. The review was carried out using robust methods and the trials were of good quality. Its findings are in line with the previous version of the review, and also with other reviews. There are some points to note: Thi...
Source: NHS News Feed - March 10, 2015 Category: Consumer Health News Tags: Heart/lungs Medication Source Type: news

More Evidence That Hormone Therapy Might Not Help Women’s Hearts
Review also found raised risk of stroke for some, although timing of use may be a key factor
Source: The Doctors Lounge - Oncology - March 10, 2015 Category: Cancer & Oncology Authors: webmaster at doctorslounge.com Tags: Gynecology, Neurology, Oncology, News, Source Type: news

Hormone therapy for preventing cardiovascular disease in post-menopausal women.
CONCLUSIONS: Our review findings provide strong evidence that treatment with hormone therapy in post-menopausal women overall, for either primary or secondary prevention of cardiovascular disease events has little if any benefit and causes an increase in the risk of stroke and venous thromboembolic events. PMID: 25754617 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - March 10, 2015 Category: Journals (General) Authors: Boardman HM, Hartley L, Eisinga A, Main C, Roqué I Figuls M, Bonfill Cosp X, Gabriel Sanchez R, Knight B Tags: Cochrane Database Syst Rev Source Type: research