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Specialty: Cardiology
Procedure: Carotid Endarterectomy

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Total 244 results found since Jan 2013.

Stroke Rounds: Early Surgery Looks Safe After tPA
(MedPage Today) -- Performing carotid endarterectomy or stenting in patients who were recently treated with thrombolytic therapy for an acute stroke appeared to be safe, an observational study showed.
Source: MedPage Today Cardiovascular - March 11, 2014 Category: Cardiology Source Type: news

A Multispecialty Consensus-Based Approach to Carotid Artery Revascularization is Feasible in Routine Clinical Practice and Results in Excellent Clinical Outcomes
Section:  Peripheral Vascular Disease Topics:  Carotid Intervention Issue Number:  Volume 3 - Issue 26 - March 2014 Author(s):  Kamal Gupta, MD1, Kelly Jo Steffen, MD1, Balasubramanium Natarajan, MD2, Mazda Biria, MD1, Vikas Singh, MD2, George Cherian, MD2 wm 123-127 Gupta March 2014.pdf Carotid artery stenting and carotid endarterectomy are complementary (rather than competing) revascularization strategies fo...
Source: The Journal of Invasive Cardiology - March 6, 2014 Category: Cardiology Authors: hmpeditor Tags: Peripheral Vascular Disease Carotid Intervention Source Type: research

Copeptin Level After Carotid Endarterectomy and Perioperative Stroke
We evaluated the prognostic value of copeptin levels in a cohort of surgical patients after elective carotid endarterectomy (CEA). Twenty-one patients with perioperative stroke were prospectively recruited. The diagnosis of cerebrovascular event (CVE) was confirmed by computed tomography. Additionally, 21 patients with CEA without any complications (control patients) were enrolled. Blood samples were taken within 3 hours of the symptom onset. Circulating copeptin level was significantly higher in patients with CVE when compared to controls (P = .025), and significantly higher in nonsurvivors than in survivors (P = .030) af...
Source: Angiology - January 6, 2014 Category: Cardiology Authors: Maravic-Stojkovic, V., Lausevic-Vuk, L. J., Obradovic, M., Jovanovic, P., Tanaskovic, S., Stojkovic, B., Isenovic, R. E., Radak, D. J. Tags: Carotid Artery Disease Source Type: research

Long‐Term Results after Carotid Stent Implantation
ConclusionThe results of our study demonstrate very low long‐term cerebral event rates after CS supporting the long‐term safety of CS. Importantly, there was no significant difference in long‐term ipsilateral versus contralateral cerebral events lending support to the hypothesis of plaque stabilization.
Source: Journal of Interventional Cardiology - November 13, 2013 Category: Cardiology Authors: HEIKE RADU, STEFAN C. BERTOG, GREG ROBERTSON, JENNIFER FRANKE, KASJA RABE, MARIUS HORNUNG, LAURA VASKELYTE, ILONA HOFMANN, HORST SIEVERT Tags: Original Investigation Source Type: research

A Direct Comparison of Early and Late Outcomes With Three Approaches to Carotid Revascularization and Open Heart Surgery
ConclusionsStaged CAS-OHS and combined CEA-OHS are associated with a similar risk of death, stroke, or MI in the short term, with both being better than staged CEA-OHS. However, the outcomes significantly favor staged CAS-OHS after the first year.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 11, 2013 Category: Cardiology Source Type: research

Carotid Revascularization Before Open Heart Surgery The Data-Driven Treatment Strategy ∗
Optimal management of high-grade obstructive carotid artery disease at the time of open heart surgery (OHS) has never been addressed in a randomized clinical trial. Data suggest that the combined approach of carotid endarterectomy (CEA) and OHS leads to a higher risk of procedural stroke (1,2,3), and, therefore, staged carotid revascularization by CEA or carotid artery stenting (CAS) is often performed before OHS. Does the staged approach lead to an overall reduction in the rate of major adverse cardiovascular events (MACE = death, myocardial infarction, and stroke) for patients with concomitant coronary and cerebrovasc...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 11, 2013 Category: Cardiology Source Type: research

Use of ACIST™ contrast injection device in carotid artery stenting in high-surgical-risk patients
Conclusions: The use of the ACIST™ device was feasible in carotid stenting in a high-risk population without an increase in end points when compared to historic controls.
Source: Cardiovascular Revascularization Medicine - October 21, 2013 Category: Cardiology Authors: Punnaiah C. Marella, Siva Talluri, Renata Schwartz, Richard R. Heuser Tags: Clinical Source Type: research

Carotid endarterectomy: where do we stand at present?
Purpose of review: The introduction of endovascular techniques and improvements in the medical management of atherosclerotic carotid lesions have led to changes in the modern management of stroke. The purpose of this review is to summarize the latest developments in surgical carotid intervention and highlight the current controversies. Recent findings: The predominant controversies that dominate the correct surgical management of carotid atherosclerotic disease are: Notwithstanding the results of the Carotid Revascularisation Endarterectomy versus Stenting Trial, does carotid artery stenting produce equivalent outcomes to ...
Source: Current Opinion in Cardiology - October 14, 2013 Category: Cardiology Tags: DISEASES OF THE AORTA, PULMONARY AND PERIPHERAL VESSELS: Edited by Alan Braverman Source Type: research

Haptoglobin 2 allele associates with unstable carotid plaque and major cardiovascular events
Conclusion: Common haptoglobin variants modulate the inflammatory response to IPH and associate with the risk of unstable carotid stenosis and major ischemic cardiovascular events.Highlights:
Source: Atherosclerosis - September 26, 2013 Category: Cardiology Authors: Petra Ijäs, Jani Saksi, Lauri Soinne, Jarno Tuimala, Matti Jauhiainen, Antti Jula, Mika Kähönen, Y. Antero Kesäniemi, Petri T. Kovanen, Markku Kaste, Perttu J. Lindsberg Tags: Clinical & Population Research - Genetics Source Type: research

A mathematical evaluation of hemodynamic parameters after carotid eversion and conventional patch angioplasty
In conclusion, in a realistically simulated carotid artery, fluid-structure interaction modeling demonstrated CEE to produce less mechanical wall stress and improved flow patterns compared with CEAP. Clinical validation with larger numbers of individual patients will ultimately be required to support modeling approaches to help predict arterial disease progression and comparative effectiveness of reconstruction methods and devices.
Source: AJP: Heart and Circulatory Physiology - September 1, 2013 Category: Cardiology Authors: Kamenskiy, A. V., Pipinos, I. I., Dzenis, Y. A., Gupta, P. K., Jaffar Kazmi, S. A., MacTaggart, J. N. Tags: INTEGRATIVE CARDIOVASCULAR PHYSIOLOGY AND PATHOPHYSIOLOGY Source Type: research

Vulnerable carotid plaques are associated with the development of early restenosis after carotid endarterectomy
Background. Carotid endarterectomy (CEA) is widely recognised as an effective surgical method in both symptomatic and asymptomatic patients with significant internal carotid artery stenosis. Although the association between vulnerable carotid plaques and stroke is well established, little is known about their role in development of myointimal hyperplasia after carotid surgery. In the current study we aimed to establish correlation between plaque morphology (as observed by ultrasonic scan) and the degree of myointimal hyperplasia after CEA.
Source: Artery Research - September 1, 2013 Category: Cardiology Authors: E.A. Surkova, O.V. Tereshina, A.N. Vachev Tags: Abstracts from Artery 13, Mermaid Conference and Events Centre, London, UK, 17–19 October 2013 Source Type: research

Carotid Revascularization Before Open Heart Surgery: The Data-Driven Treatment Strategy∗
Optimal management of high-grade obstructive carotid artery disease at the time of open heart surgery (OHS) has never been addressed in a randomized clinical trial. Data suggest that the combined approach of carotid endarterectomy (CEA) and OHS leads to a higher risk of procedural stroke , and, therefore, staged carotid revascularization by CEA or carotid artery stenting (CAS) is often performed before OHS. Does the staged approach lead to an overall reduction in the rate of major adverse cardiovascular events (MACE = death, myocardial infarction, and stroke) for patients with concomitant coronary and cerebrovascular di...
Source: Journal of the American College of Cardiology - August 2, 2013 Category: Cardiology Authors: Ehtisham Mahmud, Ryan Reeves Tags: Coronary Artery Disease: Editorial Comment Source Type: research

A Direct Comparison of Early and Late Outcomes With Three Approaches to Carotid Revascularization and Open Heart Surgery
Conclusions: Staged CAS-OHS and combined CEA-OHS are associated with a similar risk of death, stroke, or MI in the short term, with both being better than staged CEA-OHS. However, the outcomes significantly favor staged CAS-OHS after the first year.
Source: Journal of the American College of Cardiology - July 22, 2013 Category: Cardiology Authors: Mehdi H. Shishehbor, Sridhar Venkatachalam, Zhiyuan Sun, Jeevanantham Rajeswaran, Samir R. Kapadia, Christopher Bajzer, Heather L. Gornik, Bruce H. Gray, John R. Bartholomew, Daniel G. Clair, Joseph F. Sabik, Eugene H. Blackstone Tags: Coronary Artery Disease Source Type: research

Risk Factors for Cerebral Embolization After Carotid Artery Stenting With Embolic Protection: A Diffusion-Weighted Magnetic Resonance Imaging Study in 837 Consecutive Patients Peripheral Artery Disease
Conclusions— Age, hypertension, lesion morphology, and aortic arch type were predictive for procedural-related cerebral embolic lesions during embolic protected CAS. Age, significant contralateral carotid stenosis, and complex aortic arch type were predictive for bilateral ischemic lesions. The clinical implications of ischemic lesions are not yet fully understood.
Source: Circulation: Cardiovascular Interventions - June 18, 2013 Category: Cardiology Authors: Bijuklic, K., Wandler, A., Varnakov, Y., Tuebler, T., Schofer, J. Tags: Carotid Stenosis, Computerized tomography and Magnetic Resonance Imaging, Angioplasty and Stenting Peripheral Artery Disease Source Type: research

Need for new non-invasive imaging strategies to identify high-risk asymptomatic patients with carotid stenosis
We fully agree with Dr. Naylor and Spence's concerns about the current treatment of asymptomatic patients with carotid stenosis . The authors underlined that the indication for approximately 90% of carotid endarterectomy (CEA) and stenting is for asymptomatic carotid stenosis , based on extrapolation from the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST), a modern study of stenting versus endarterectomy without a medical arm of therapy , to historical results from the medical arms of 2 early studies of CEA, the Asymptomatic Carotid Atherosclerosis Study (ACAS) and the Asymptomatic Carotid Stenosis ...
Source: International Journal of Cardiology - June 3, 2013 Category: Cardiology Authors: Enrico Ammirati, Marco Magnoni, Paolo G. Camici Tags: Letters to the Editor Source Type: research