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Specialty: Cardiology
Nutrition: Diets

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Total 303 results found since Jan 2013.

Endothelial Damage Arising From High Salt Hypertension Is Elucidated by Vascular Bed Systematic Profiling
CONCLUSIONS: These findings provide novel molecular insight into HS-induced structural changes in eGC and EC composition that may increase cardiovascular risk and potentially guide the development of new diagnostics and therapeutic interventions.PMID:36700429 | DOI:10.1161/ATVBAHA.122.318439
Source: Arteriosclerosis, Thrombosis and Vascular Biology - January 26, 2023 Category: Cardiology Authors: Arada Vinaiphat Kalailingam Pazhanchamy Gnanasekaran JebaMercy SoFong Cam Ngan Melvin Khee-Shing Leow Hee Hwa Ho Yong-Gui Gao Kah Leong Lim A Mark Richards Dominique P V de Kleijn Christopher P Chen Raj N Kalaria Jian Liu Deborah D O'Leary Neil E McCarthy Source Type: research

Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
CONCLUSIONS: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.PMID:36695182 | DOI:10.1161/CIR.0000000000001123
Source: Circulation - January 25, 2023 Category: Cardiology Authors: Connie W Tsao Aaron W Aday Zaid I Almarzooq Cheryl A M Anderson Pankaj Arora Christy L Avery Carissa M Baker-Smith Andrea Z Beaton Amelia K Boehme Alfred E Buxton Yvonne Commodore-Mensah Mitchell S V Elkind Kelly R Evenson Chete Eze-Nliam Setri Fugar Giul Source Type: research

Association between dietary inflammatory index and atherosclerosis cardiovascular disease in U.S. adults
CONCLUSION: Our study revealed a positive and non-linearly association between DII and ASCVD in U.S. adults. This relationship was more pronounced in females. The findings provide a reference for future research and diet recommendations.PMID:36687707 | PMC:PMC9849765 | DOI:10.3389/fnut.2022.1044329
Source: Atherosclerosis - January 23, 2023 Category: Cardiology Authors: Jie Zhang Jundi Jia Runmin Lai Xinyi Wang Xuanye Chen Wende Tian Qiyu Liu Jingen Li Jianqing Ju Hao Xu Source Type: research

Pharmacological and Molecular Insight on the Cardioprotective Role of Apigenin
Nutrients. 2023 Jan 12;15(2):385. doi: 10.3390/nu15020385.ABSTRACTApigenin is a naturally occurring dietary flavonoid found abundantly in fruits and vegetables. It possesses a wide range of biological properties that exert antioxidant, anti-inflammatory, anticancer, and antibacterial effects. These effects have been reported to be beneficial in the treatment of atherosclerosis, stroke, hypertension, ischemia/reperfusion-induced myocardial injury, and diabetic cardiomyopathy, and provide protection against drug-induced cardiotoxicity. These potential therapeutic effects advocate the exploration of the cardioprotective actio...
Source: Atherosclerosis - January 21, 2023 Category: Cardiology Authors: Shilu Deepa Thomas Niraj Kumar Jha Saurabh Kumar Jha Bassem Sadek Shreesh Ojha Source Type: research

Microarray Expression Profile of Myricetin-Treated THP-1 Macrophages Exhibits Alterations in Atherosclerosis-Related Regulator Molecules and LXR/RXR Pathway
Int J Mol Sci. 2022 Dec 23;24(1):278. doi: 10.3390/ijms24010278.ABSTRACTAtherosclerosis is a chronic inflammation characterized by macrophage infiltration, lipid deposition, and arterial wall thickening. Prevention of atherosclerosis by nutraceuticals is gaining attention. Myricetin, a dietary flavonol, is claimed to possess anti-atherosclerosis properties. We studied myricetin's effect on the atherosclerosis-associated molecular mechanism. Cytotoxicity and proliferation testing to check the viability of myricetin-treated THP-1 macrophages and monocyte migration study in the presence and absence of myricetin was performed....
Source: Atherosclerosis - January 8, 2023 Category: Cardiology Authors: Etimad Huwait Rehab Almassabi Sanaa Almowallad Salma Saddeek Sajjad Karim Gauthaman Kalamegam Zeenat Mirza Source Type: research

Intake of marine and plant-derived n-3 fatty acids and development of atherosclerotic cardiovascular disease in the Danish Diet, Cancer and Health cohort
CONCLUSIONS: A high intake of marine n-3 PUFA was associated with a lower risk of total ASCVD and acute major ischemic events, whereas no association could be demonstrated for the plant-derived ALA.PMID:36592188 | DOI:10.1007/s00394-022-03081-w
Source: Atherosclerosis - January 2, 2023 Category: Cardiology Authors: Christian S Bork S øren Lundbye-Christensen Stine K Ven ø Anne N Lasota Anne Tj ønneland Erik B Schmidt Kim Overvad Source Type: research

Fecal level of butyric acid, a microbiome-derived metabolite, is increased in patients with severe carotid atherosclerosis
Sci Rep. 2022 Dec 26;12(1):22378. doi: 10.1038/s41598-022-26759-x.ABSTRACTThe short-chain fatty acid (SCFA) butyric acid maintains a healthy gut barrier and vascular endothelium. We aimed to investigate the association between fecal butyric acid, carotid atherosclerosis and risk factors for ischemic stroke. Patients with severe carotid atherosclerosis (i.e. ≥ 50% stenosis) (n = 43) were compared with healthy controls (n = 38). We analyzed fecal SCFAs by gas chromatography, microbiota composition by 16S rRNA sequencing, markers of gut barrier damage and inflammasome activation by immunoassay, and plasma SCFAs by ultra-hig...
Source: Atherosclerosis - December 26, 2022 Category: Cardiology Authors: Kristine St ø J ørgen Valeur Thor Ueland Gunn Helen Malmstr øm Vigdis Bjerkeli Marius Tr øseid Johannes R Hov Kristian Holm Beate Vestad Bente Halvorsen Mona Skjelland Karolina R Skagen Source Type: research

Influence of Management of Intensive Weight, Blood Pressure, and Lipids on Disease Severity in Patients with Carotid Atherosclerosis
CONCLUSIONS: A program for management of body weight, blood pressure, and blood lipids can effectively control the severity of carotid atherosclerosis, can prevent the disease's progression, and can be promoted as a clinical application.PMID:36455146
Source: Atherosclerosis - December 1, 2022 Category: Cardiology Authors: Yongjian Liu Xiaojing Yan Jin Zhou Litao Chen Zhixing Du Jianmin Pang Liya Jiao Dan Li Yongmin Deng Source Type: research

Pristane attenuates atherosclerosis in Apoe < sup > -/- < /sup > mice via IL-4-secreting regulatory plasma cell-mediated M2 macrophage polarization
Biomed Pharmacother. 2022 Nov;155:113750. doi: 10.1016/j.biopha.2022.113750. Epub 2022 Sep 29.ABSTRACTAtherosclerosis, an inflammatory progressive vascular disease, causes heart disease and stroke worldwide. B cells with immune suppressive functions have been implicated in autoimmune, inflammatory, and cardiovascular diseases. However, the precise role of regulatory B cells and the interaction with macrophages in atherosclerosis remains undefined. In our study, eight-week-old female apolipoprotein E null (Apoe-/-) mice were treated with a single dose of vehicle or pristane and then placed on an atherogenic diet for 12 week...
Source: Atherosclerosis - October 22, 2022 Category: Cardiology Authors: Yimin Huang Kongyang Ma Rencai Qin Yaxiong Fang Jingquan Zhou Xiaoyan Dai Source Type: research