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Nutrition: Antidoxidants
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Total 64 results found since Jan 2013.
Role of Vitamins in Cardiovascular Health: Know Your Facts - Part 1
Curr Vasc Pharmacol. 2023 Sep 12. doi: 10.2174/1570161121666230912155548. Online ahead of print.ABSTRACTCardiovascular (CV) disease (CVD) is a major cause of morbidity and mortality world-wide, thus it is important to adopt preventive interventions. Observational data demonstrating CV benefits of vitamin supplements, advanced by self-proclaimed experts have resulted in ~50% of Americans reporting the use of multivitamins for health promotion; this practice has led to a multi-billion-dollar business of the multivitamin-industry. However, the data on the extensive use of multivitamins show no consistent benefit for CVD preve...
Source: Atherosclerosis - September 13, 2023 Category: Cardiology Authors: Antonis A Manolis Theodora A Manolis Helen Melita Antonis S Manolis Source Type: research
Role of Vitamins in Cardiovascular Health: Know Your Facts-Part 2
Curr Vasc Pharmacol. 2023 Sep 11. doi: 10.2174/1570161121666230911115725. Online ahead of print.ABSTRACTCardiovascular disease (CVD) is a major cause of morbidity/mortality world-wide, hence preventive interventions are crucial. Observational data showing beneficial CV-effects of vitamin supplements, promoted by self-proclaimed experts, have led to ~50% of Americans using multivitamins; this practice has culminated into a multi-billion-dollar business. However, robust evidence is lacking, and certain vitamins might incur harm. This two-part review focuses on the attributes or concerns about specific vitamin consumption on ...
Source: Atherosclerosis - September 11, 2023 Category: Cardiology Authors: Antonis A Manolis Theodora A Manolis Helen Melita Antonis S Manolis Source Type: research
Dietary Flavonoid Intake and Carotid Calcification in Patients with Ischemic Stroke
CONCLUSION: Dietary flavonoid intake is associated with carotid calcification, and, therefore, may influence the risk of stroke occurrence and recurrence.PMID:37524067 | DOI:10.1159/000532117
Source: Atherosclerosis - July 31, 2023 Category: Cardiology Authors: Tao Mou Xuerong Jia Min Peng Xiang Li Yaqian Xia Yantong Chen Qing Wang Xiaoke Wang Xinfeng Liu Gelin Xu Source Type: research
Clinical Potential of Hydrogen Sulfide in Peripheral Arterial Disease
Int J Mol Sci. 2023 Jun 9;24(12):9955. doi: 10.3390/ijms24129955.ABSTRACTPeripheral artery disease (PAD) affects more than 230 million people worldwide. PAD patients suffer from reduced quality of life and are at increased risk of vascular complications and all-cause mortality. Despite its prevalence, impact on quality of life and poor long-term clinical outcomes, PAD remains underdiagnosed and undertreated compared to myocardial infarction and stroke. PAD is due to a combination of macrovascular atherosclerosis and calcification, combined with microvascular rarefaction, leading to chronic peripheral ischemia. Novel therap...
Source: Atherosclerosis - June 28, 2023 Category: Cardiology Authors: Cl émence Bechelli Diane Macabrey Sebastien Deglise Florent Allagnat Source Type: research
Antioxidant action of xanthine oxidase inhibitor febuxostat protects the liver and blood vasculature in SHRSP5/Dmcr rats
CONCLUSIONS: Overall, the XO inhibitor febuxostat exerted protective effects against NASH and atherosclerosis in SHRSP5/Dmcr rats.PMID:37376883 | DOI:10.32725/jab.2023.009
Source: Atherosclerosis - June 28, 2023 Category: Cardiology Authors: Mai Kakimoto Moe Fujii Ikumi Sato Koki Honma Hinako Nakayama Sora Kirihara Taketo Fukuoka Shang Ran Satoshi Hirohata Kazuya Kitamori Shusei Yamamoto Shogo Watanabe Source Type: research
Association between dietary antioxidant capacity and atherosclerotic carotid stenosis in patients with ischemic stroke
CONCLUSIONS: DTAC may influence the initiation and development of atherosclerosis, and, therefore, the risk of ischemic stroke.PMID:37210776 | DOI:10.1016/j.jstrokecerebrovasdis.2023.107148
Source: Atherosclerosis - May 21, 2023 Category: Cardiology Authors: Jizi Ma Xuerong Jia Yaqian Xia Min Peng Yantong Chen Jingjing Cai Xinfeng Liu Gelin Xu Source Type: research
< em > In-vitro < /em > antioxidant, lipoxygenase inhibitory, and < em > in-vivo < /em > muscle relaxant potential of the extract and constituent isolated from < em > Diospyros kaki < /em > (Japanese Persimmon)
This study excellently rationalizes the traditional usage of D. kaki in curing various diseases. Furthermore, the docking results indicate, that the isolated compound fits well into the active site of the lipoxygenase, and makes strong interactions with the target protein.PMID:36895410 | PMC:PMC9989937 | DOI:10.1016/j.heliyon.2023.e13816
Source: Atherosclerosis - March 10, 2023 Category: Cardiology Authors: Adil Mujawah Abdur Rauf Sami Bawazeer Abdul Wadood Hassan A Hemeg Saud Bawazeer Source Type: research
Emerging role of miRNAs in the regulation of ferroptosis
Front Mol Biosci. 2023 Feb 15;10:1115996. doi: 10.3389/fmolb.2023.1115996. eCollection 2023.ABSTRACTFerroptosis is a kind of cell death which has distinctive features differentiating it from autophagy, necrosis and apoptosis. This iron-dependent form of cell death is described by an increase in lipid reactive oxygen species, shrinkage of mitochondria and decrease in mitochondrial cristae. Ferroptosis is involved in the initiation and progression of many diseases and is regarded as a hotspot of investigations on treatment of disorders. Recent studies have shown that microRNAs partake in the regulation of ferroptosis. The im...
Source: Atherosclerosis - March 6, 2023 Category: Cardiology Authors: Reza Mahmoudi-Lamouki Sepideh Kadkhoda Bashdar Mahmud Hussen Soudeh Ghafouri-Fard Source Type: research
Oxidative stress in cerebrovascular disease and associated diseases
Front Endocrinol (Lausanne). 2023 Feb 17;14:1124419. doi: 10.3389/fendo.2023.1124419. eCollection 2023.ABSTRACTCellular aging is the most severe risk factor for neurodegenerative disease. Simultaneously, oxidative stress (OS) is a critical factor in the aging process, resulting from an imbalance between reactive oxygen and nitrogen species and the antioxidant defense system. Emerging evidence indicates that OS is a common cause of several age-related brain pathologies, including cerebrovascular diseases. Elevated OS disrupts endothelial functional ability by diminishing the bioavailability of nitric oxide (a vascular dilat...
Source: Atherosclerosis - March 6, 2023 Category: Cardiology Authors: Vijay Kumar Kausik Bishayee Soochul Park Unjoo Lee Jaebong Kim Source Type: research
Bioactive Compounds (BACs): A Novel Approach to Treat and Prevent Cardiovascular Diseases
Curr Probl Cardiol. 2023 Feb 23:101664. doi: 10.1016/j.cpcardiol.2023.101664. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs) are one of the leading disorders of serious death and cause huge economic loss to patients and society. It is estimated that about 18 million people have a high death ratio due to the incidence of CVDs such as (stroke, coronary heart disease, and non-ischemic heart failure). Bioactive compounds (BACs) are healthy nutritional ingredients providing beneficial effects and nutritional value to the human body. Epidemiological studies strongly shed light on several bioactive compounds that ar...
Source: Atherosclerosis - February 25, 2023 Category: Cardiology Authors: Syed Riaz Ud Din Sumbul Saeed Shahid Ullah Khan Mintao Zhong Source Type: research
Role of polyphenolic compounds and their nanoformulations: a comprehensive review on cross-talk between chronic kidney and cardiovascular diseases
Naunyn Schmiedebergs Arch Pharmacol. 2023 Feb 24. doi: 10.1007/s00210-023-02410-y. Online ahead of print.ABSTRACTChronic kidney disease (CKD) affects a huge portion of the world's population and frequently leads to cardiovascular diseases (CVDs). It might be because of common risk factors between chronic kidney disease and cardiovascular diseases. Renal dysfunction caused by chronic kidney disease creates oxidative stress which in turn leads to cardiovascular diseases. Oxidative stress causes endothelial dysfunction and inflammation in heart which results in atherosclerosis. It ends in clogging of veins and arteries that c...
Source: Atherosclerosis - February 24, 2023 Category: Cardiology Authors: Ankita Rajput Palvi Sharma Davinder Singh Sharabjit Singh Prabhjot Kaur Shivani Attri Pallvi Mohana Harneetpal Kaur Farhana Rashid Astha Bhatia Joachim Jankowski Vanita Arora Hardeep Singh Tuli Saroj Arora Source Type: research
Pharmacological and Molecular Insight on the Cardioprotective Role of Apigenin
Nutrients. 2023 Jan 12;15(2):385. doi: 10.3390/nu15020385.ABSTRACTApigenin is a naturally occurring dietary flavonoid found abundantly in fruits and vegetables. It possesses a wide range of biological properties that exert antioxidant, anti-inflammatory, anticancer, and antibacterial effects. These effects have been reported to be beneficial in the treatment of atherosclerosis, stroke, hypertension, ischemia/reperfusion-induced myocardial injury, and diabetic cardiomyopathy, and provide protection against drug-induced cardiotoxicity. These potential therapeutic effects advocate the exploration of the cardioprotective actio...
Source: Atherosclerosis - January 21, 2023 Category: Cardiology Authors: Shilu Deepa Thomas Niraj Kumar Jha Saurabh Kumar Jha Bassem Sadek Shreesh Ojha Source Type: research
Air Pollution: Another Threat to HDL Function
Int J Mol Sci. 2022 Dec 24;24(1):317. doi: 10.3390/ijms24010317.ABSTRACTEpidemiological studies have consistently demonstrated a positive association between exposure to air pollutants and the incidence of cardiovascular disease, with the strongest evidence for particles with a diameter < 2.5 μm (PM2.5). Therefore, air pollution has been included among the modifiable risk factor for cardiovascular outcomes as cardiovascular mortality, acute coronary syndrome, stroke, heart failure, and arrhythmias. Interestingly, the adverse effects of air pollution are more pronounced at higher levels of exposure but were also sho...
Source: Atherosclerosis - January 8, 2023 Category: Cardiology Authors: Alice Ossoli Federica Cetti Monica Gomaraschi Source Type: research
Glutathione: A Samsonian life-sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation
Front Nutr. 2022 Nov 1;9:1007816. doi: 10.3389/fnut.2022.1007816. eCollection 2022.ABSTRACTMany local and systemic diseases especially diseases that are leading causes of death globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart disease and stroke, cancer and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 19 (COVID-19), involve both, (1) oxidative stress with excessive production of reactive oxygen species (ROS) that lower glutathione (GSH) levels, and (2) inflammation. The GSH tripeptide (γ- L-glutamyl-L-cysteinyl-glycine), the most abundant w...
Source: Atherosclerosis - November 17, 2022 Category: Cardiology Authors: Carlos A Labarrere Ghassan S Kassab Source Type: research
