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Specialty: Cardiology
Condition: Aortic Aneurysm

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Total 129 results found since Jan 2013.

Outcomes of aortic valve-sparing root replacement with cusp repair in connective tissue disease
CONCLUSION: Remodelling and aortic valve repair showed excellent durability at 5 years, even in connective tissue disorders.PMID:37640626 | DOI:10.1016/j.acvd.2023.07.005
Source: Archives of Cardiovascular Diseases - August 28, 2023 Category: Cardiology Authors: Pichoy Danial Pierre Demondion Mathieu Debauchez Pascal Leprince Emmanuel Lansac Source Type: research

The multiple roles of lysophosphatidic acid in vascular disease and atherosclerosis
Curr Opin Lipidol. 2023 Jul 28. doi: 10.1097/MOL.0000000000000890. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: To explore the multiple roles that lysophosphatidic acid (LPA) plays in vascular disease and atherosclerosis.RECENT FINDINGS: A high-fat high-cholesterol diet decreases antimicrobial activity in the small intestine, which leads to increased levels of bacterial lipopolysaccharide in the mucus of the small intestine and in plasma that increase systemic inflammation, and enhance dyslipidemia and aortic atherosclerosis. Decreasing LPA production in enterocytes reduces the impact of the diet. LPA signaling inhibit...
Source: Atherosclerosis - July 27, 2023 Category: Cardiology Authors: Arnab Chattopadhyay Srinivasa T Reddy Alan M Fogelman Source Type: research

Associations of Tissue and Soluble LOX-1 with Human Abdominal Aortic Aneurysm
Conclusions In AAA, sLOX-1 was differently affected by age, cardiometabolic diseases, and corresponding medical therapies. Comparison with nonatherosclerotic disease would be beneficial to further elucidate the diagnostic potential of sLOX-1, although it was not useful for risk stratification. Aneurysmal LOX-1 mRNA expression was increased and positively associated with smooth muscle cells and collagen content, suggesting that LOX-1 is eventually not deleterious in human AAA and could counteract AAA rupture.PMID:37421287 | DOI:10.1161/JAHA.122.027537
Source: Atherosclerosis - July 8, 2023 Category: Cardiology Authors: Anja Hofmann Yazan Khorzom Anna Klimova Steffen Wolk Albert Busch Pamela Sabarstinski Margarete M üglich Dmitry Egorov Irakli Kopaliani David M Poitz Marvin Kapalla Bianca Hamann Frieda Frank Christian J änichen Coy Brunssen Henning Morawietz Christian Source Type: research

Elective ascending aortic aneurysm repair outcomes in a nationwide US cohort
Conclusions The overall rate of in-hospital death, stroke and MI is nearly 5% in patients undergoing elective ascending aortic aneurysm repair. Among several predictors, chronic weight loss is associated with the largest increase in the risk of poor outcomes. Higher hospital volume is associated with a lower in-hospital mortality, highlighting the importance to refer patients to high-volume centres while discussing the risks and benefits of proceeding with repair.
Source: Heart - June 26, 2023 Category: Cardiology Authors: Beyer, S. E., Secemsky, E. A., Khabbaz, K., Carroll, B. J. Tags: Aortic and vascular disease Source Type: research

Procedural and long-term outcomes of elective endovascular abdominal aortic aneurysm repair in octogenarians
CONCLUSION: In octogenarian patients with AAA, EVAR represents a safe procedure both during the index hospitalization and during long-term follow-up.PMID:37355984 | DOI:10.24875/ACM.22000289
Source: Archivos de Cardiologia de Mexico - June 25, 2023 Category: Cardiology Authors: Fernando Garagoli Juan Guido-Chiabrando Jos é Gaspar-Chas Mart ín Rabellino Ignacio Mart ín Bluro Source Type: research

Blood phytosterols in relation to cardiovascular diseases and mediating effects of blood lipids and hematological traits: a Mendelian randomization analysis
CONCLUSION: The study suggests that genetic predisposition to higher blood total sitosterol is linked to a greater risk of major CVDs. Moreover, blood nonHDL-C and apolipoprotein B might mediate a significant proportion of the associations between sitosterol and coronary diseases.PMID:37270173 | DOI:10.1016/j.metabol.2023.155611
Source: Atherosclerosis - June 3, 2023 Category: Cardiology Authors: Yimin Zhao Zhenhuang Zhuang Yueying Li Wendi Xiao Zimin Song Ninghao Huang Wenxiu Wang Xue Dong Jinzhu Jia Tao Huang Source Type: research

Clonal Hematopoiesis and the Heart: a Toxic Relationship
Curr Oncol Rep. 2023 Mar 15. doi: 10.1007/s11912-023-01398-1. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Clonal hematopoiesis (CH) refers to the expansion of hematopoietic stem cell clones and their cellular progeny due to somatic mutations, mosaic chromosomal alterations (mCAs), or copy number variants which naturally accumulate with age. CH has been linked to increased risk of blood cancers, but CH has also been linked to adverse cardiovascular outcomes.RECENT FINDINGS: A combination of clinical outcome studies and mouse models have offered strong evidence that CH mutations either correlate with or cause atheroscle...
Source: Atherosclerosis - March 15, 2023 Category: Cardiology Authors: Jeffrey L Jensen Saumya Easaw Travis Anderson Yash Varma Jiandong Zhang Brian C Jensen Catherine C Coombs Source Type: research

Outcomes of endovascular repair of infrarenal penetrating aortic ulcers
Conclusions: According to this registry data, endovascular repair of PAU is technically feasible with acceptable perioperative outcomes, but further studies investigating mid- and long-term data are needed before invasive treatment of PAU disease in an elderly and comorbid patient population should be recommended.PMID:36880201 | DOI:10.1024/0301-1526/a001060
Source: Atherosclerosis - March 7, 2023 Category: Cardiology Authors: Johannes Hatzl Christian-Alexander Behrendt Thomas Schmitz-Rixen Reinhart Thomas Grundmann Markus Steinbauer Dittmar B öckler Christian Uhl DIGG Investigators Source Type: research