• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Haemorrhagic stroke in term and late preterm neonates
Conclusions In our cohort with acute HS, most presented with seizures, apnoea and/or poor feeding. Fetal distress and CHD were common. Nearly two-thirds had intraparenchymal with intraventricular haemorrhage. Over half were due to haemorrhagic transformation of infarction. Short-term neurologic deficits were present in 47% of survivors.
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - December 13, 2013 Category: Perinatology & Neonatology Authors: Bruno, C. J., Beslow, L. A., Witmer, C. M., Vossough, A., Jordan, L. C., Zelonis, S., Licht, D. J., Ichord, R. N., Smith, S. E. Tags: Epidemiologic studies, Congenital heart disease, Drugs: cardiovascular system, Drugs: CNS (not psychiatric), Epilepsy and seizures, Hydrocephalus, Stroke, Pregnancy, Child health Original articles Source Type: research

Predictive value of the amplitude integrated EEG in infants with hypoxic ischaemic encephalopathy: data from a randomised trial of therapeutic hypothermia
The amplitude integrated EEG (aEEG) is reputed to be one of the best predictors of neurological outcome following hypoxic ischaemic encephalopathy in term newborns and was used to select infants into trials of neuroprotection with hypothermia, but its predictive value and the effect of moderate hypothermia on the aEEG have not previously been examined in a randomised study. The positive predictive value (PPV) of the aEEG recorded within 6 h of birth for death or disability at 18 months of age was determined in 314 infants born after 35 weeks gestation who were randomised to receive standard care with or with...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - December 13, 2013 Category: Perinatology & Neonatology Authors: Azzopardi, D., on behalf of the TOBY study group Tags: Clinical trials (epidemiology), Open access, Stroke Short research reports Source Type: research

Giant transient pustular melanosis in an infant
An otherwise healthy male newborn infant was admitted directly from the delivery room because of multiple pustular lesions spread throughout the body just after his birth. He was born at term, without perinatal problems. There was no history of maternal infection. Upon physical examination, the infant was afebrile, pink and active, breathing sounds were clear and heart rate was regular. However, multiple giant pustules with yellowish contents, approximately 0.5–1 cm in diameter, were found over the forehead, neck, abdomen and genital area (figure 1). The pustules have ruptured and gradually faded from the second...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - October 10, 2013 Category: Perinatology & Neonatology Authors: Paloni, G., Cutrone, M. Tags: Journalology, Stroke, Child health, Airway biology, Dermatology, Competing interests (ethics) Images in neonatal medicine Source Type: research

Transition from fetal to neonatal life: Changes in cardiac function assessed by speckle-tracking echocardiography
Conclusion: Speckle-tracking echocardiography is a feasible and reproducible technique in analyzing both fetal and newborn cardiac functions. Therefore, it might be useful in clinical routine examinations and give new insights in transitional physiology.
Source: Early Human Development - September 18, 2013 Category: Perinatology & Neonatology Authors: Ulf Schubert, Matthias Müller, Mikael Norman, Hashim Abdul-Khaliq Source Type: research

Anticonvulsant effect of xenon on neonatal asphyxial seizures
We examined seizure activity on the real time and amplitude integrated EEG records of 14 full-term infants with perinatal asphyxial encephalopathy treated within 12 h of birth with 30% inhaled xenon for 24 h combined with 72 h of moderate systemic hypothermia. Seizures were identified on 5 of 14 infants. Seizures stopped during xenon therapy but recurred within a few minutes of withdrawing xenon and stopped again after xenon was restarted. Our data show that subanaesthetic levels of xenon may have an anticonvulsant effect. Inhaled xenon may be a valuable new therapy in this hard-to-treat population.
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2013 Category: Perinatology & Neonatology Authors: Azzopardi, D., Robertson, N. J., Kapetanakis, A., Griffiths, J., Rennie, J. M., Mathieson, S. R., Edwards, A. D., Deierl, Merchant, Srinivasan, Viac, Kendall, Dinan, Uria, Nandiran, Turner, Wallace, Franks, Maze, Fagiolo, Hajnal, Charles-Edwards, Cady, Ab Tags: Drugs: CNS (not psychiatric), Epilepsy and seizures, Stroke, Child health, Drugs: psychiatry Short research reports Source Type: research

To cool or not to cool? Hypothermia treatment outside trial criteria
This article reviews several clinical scenarios where cooling may be considered for neuroprotection and provides practical management guidance based on available evidence. The authors emphasise the importance of clear communication with parents and of maintaining national registers to record practices.
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2013 Category: Perinatology & Neonatology Authors: Austin, T., Shanmugalingam, S., Clarke, P. Tags: Reviews Source Type: research

Seizures in pregnancy: Epilepsy, eclampsia, and stroke
Abstract: Seizures during pregnancy complicate
Source: Seminars in Perinatology - August 1, 2013 Category: Perinatology & Neonatology Authors: Laura A. Hart, Baha M. Sibai Source Type: research

Epidemiology and aetiology of neonatal seizures
Summary: Neonatal seizures constitute the most frequent and distinctive neurological symptom in the neonatal period. Seizures in the neonatal period differ considerably from those observed later in life with respect to their aetiological profile and clinical presentation. In addition, the aetiological profile in preterm infants is different from that seen in term infants. Hypoxic–ischaemic encephalopathy is the most frequent cause of neonatal seizures in term babies followed by focal ischaemia (stroke), cerebral malformations and metabolic disturbances. In preterm neonates, intraventricular haemorrhage and infections cau...
Source: Seminars in Fetal and Neonatal Medicine - June 7, 2013 Category: Perinatology & Neonatology Authors: Chakrapani Vasudevan, Malcolm Levene Source Type: research

Correction
Rutherford M A, Ramenghi L A, Cowan F M. Neonatal stroke. This paper was published in print with an incorrect doi. The print citation is Arch Dis Child Fetal Neonatal Ed 2012;97:F377–84.
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - February 15, 2013 Category: Perinatology & Neonatology Tags: Corrections Source Type: research

Pages: 1  2  3  4  5  6  7