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Specialty: Cancer & Oncology
Source: Cancer Control

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Total 161 results found since Jan 2013.

Chronic Oxidative Stress as a Marker of Long-term Radiation-Induced Cardiovascular Outcomes in Breast Cancer
We examined associations of biomarkers of oxidative stress (myeloperoxidase, growth differentiation factor-15, 8-hydroxy-2'-deoxyguanosine [8-OH-dG], placental growth factor), cardiac injury (troponin I, cystatin-C), inflammation (interleukin-6, C-reactive protein), and myocardial fibrosis (transforming growth factor-ß) with long-term RICVD in breast cancer (BC) survivors. We conducted a nested case-control study within the Women's Health Initiative of postmenopausal women with incident BC stages I-III, who received radiation and had pre- and post-BC diagnosis serum samples. Cases (n = 55) were defined as developing incid...
Source: Cancer Control - September 30, 2022 Category: Cancer & Oncology Authors: Alexi Vasbinder Richard K Cheng Susan R Heckbert Hilaire Thompson Oleg Zaslavksy Rowan T Chlebowski Aladdin H Shadyab Lisa Johnson Jean Wactawski-Wende Gretchen Wells Rachel Yung Lisa Warsinger Martin Electra D Paskett Kerryn Reding Source Type: research

Cigarette Smoking Among US Adults With Selected Chronic Diseases Associated With Smoking, 2010-2019
CONCLUSION: Overall, smoking prevalence remains high and relatively unchanged among people with chronic diseases associated with smoking, even as the overall prevalence of cigarette smoking in the US continues to decrease. The lack of progress in smoking cessation among adults with chronic diseases associated with smoking suggests that access, promotion, and integration of cessation treatment across the continuum of health care (ie, oncology, pulmonology, and cardiology settings) may be important in the success of smoking cessation in this population.PMID:36173703 | DOI:10.5888/pcd19.220086
Source: Cancer Control - September 29, 2022 Category: Cancer & Oncology Authors: Caitlin G Loretan Monica E Cornelius Ahmed Jamal Yiling J Cheng David M Homa Source Type: research

Enhanced autophagy interacting proteins negatively correlated with the activation of apoptosis-related caspase family proteins after focal ischemic stroke of young rats
CONCLUSIONS: Collectively, the present results suggest that the the reduced levels of neuronal death after CIR in young rats were closely related to enhanced levels of autophagy and reduced levels of pro-apoptosis in neurons.PMID:36171540 | DOI:10.1186/s12868-022-00740-w
Source: Cancer Control - September 28, 2022 Category: Cancer & Oncology Authors: Jie Wang Zihao Xia Peng Sheng Mengmeng Shen Lidong Ding Dezhi Liu Bing Chun Yan Source Type: research

Understanding knowledge of hypertension among affected individuals in low-Income (B40) communities in Malaysia: The RESPOND study
CONCLUSION: This study provides reassurance that individuals with hypertension in disadvantaged communities in Malaysia have a relatively good understanding of hypertension. Further research should explore the challenges they face on their therapeutic journeys.PMID:36169064
Source: Cancer Control - September 28, 2022 Category: Cancer & Oncology Authors: F Ariffin M R Isa M N Nafiza M Y Mazapuspavina A M Fadhlina B Palafox M McKee Source Type: research

Endovascular therapy for acute ischemic stroke in patients with active malignancy: a meta-analysis with trial sequential analysis
CONCLUSION: Although a quarter of patients with active malignancy and AIS regained functional independence, physicians and patients should consider whether to apply EVT in patients with active malignancy.PMID:36163348 | DOI:10.1136/jnis-2022-019489
Source: Cancer Control - September 26, 2022 Category: Cancer & Oncology Authors: Hong-Jie Jhou Li-Yu Yang Po-Huang Chen Cho-Hao Lee Source Type: research

Is the rule of halves in hypertension valid uniformly across India? A cross-sectional analysis of national family health survey-4 data
CONCLUSION: The rule of halves of India shows that the National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases, and Stroke has made relatively good progress with the detection of hypertension and achieving BP control among those on treatment. However, with three-fourth of known hypertensives not availing treatment, more dividends from the detection of hypertension efforts could be realized. The program needs to especially focus on ensuring the treatment for those detected with hypertension.PMID:36149103 | DOI:10.4103/ijph.ijph_2143_21
Source: Cancer Control - September 23, 2022 Category: Cancer & Oncology Authors: Mohd Maroof Nafis Faizi Pruthu Thekkur Sonika Raj Sonu Goel Source Type: research

Mortality and Morbidity Effects of Long-Term Exposure to Low-Level PM < sub > 2.5 < /sub > , BC, NO < sub > 2 < /sub > , and O < sub > 3 < /sub > : An Analysis of European Cohorts in the ELAPSE Project
CONCLUSIONS: Long-term exposure to PM2.5, NO2, and BC was positively associated with natural-cause and cause-specific mortality in the pooled cohort and the administrative cohorts. Associations were found well below current limit values and guidelines for PM2.5 and NO2. Associations tended to be supralinear, with steeper slopes at low exposures with no indication of a threshold. Two-pollutant models documented the importance of characterizing the ambient mixture with both NO2 and PM2.5. We mostly found negative associations with O3. In two-pollutant models with NO2, the negative associations with O3 were attenuated to esse...
Source: Cancer Control - September 15, 2022 Category: Cancer & Oncology Authors: Brunekreef Bert Strak Maciej Chen Jie J Andersen Zorana Atkinson Richard Bauwelinck Mariska Bellander Tom Boutron Marie-Christine Brandt J ørgen Carey Iain Cesaroni Giulia Forastiere Francesco Fecht Daniela Gulliver John Hertel Ole Hoffmann Barbara de Ho Source Type: research

Recent advances in drug delivery and targeting to the brain
J Control Release. 2022 Aug 31:S0168-3659(22)00574-0. doi: 10.1016/j.jconrel.2022.08.051. Online ahead of print.ABSTRACTOur body keeps separating the toxic chemicals in the blood from the brain. A significant number of drugs do not enter the central nervous system (CNS) due to the blood-brain barrier (BBB). Certain diseases, such as tumor growth and stroke, are known to increase the permeability of the BBB. However, the heterogeneity of this permeation makes it difficult and unpredictable to transport drugs to the brain. In recent years, research has been directed toward increasing drug penetration inside the brain, and na...
Source: Cancer Control - September 3, 2022 Category: Cancer & Oncology Authors: Bharti Sethi Virender Kumar Kalika Mahato Donald W Coulter Ram I Mahato Source Type: research

Computed Tomography Angiography Quantification of Intracranial and Extracranial Vascular Narrowing in Ischemic Stroke: Differences Between Patients With and Without Illicit Drug Use
CONCLUSIONS: By using computed tomography angiography, we found that stroke patients with history of cocaine consumption had a higher incidence of intracranial circulation narrowing compared with matched controls.PMID:36055121 | DOI:10.1097/RCT.0000000000001367
Source: Cancer Control - September 2, 2022 Category: Cancer & Oncology Authors: Eliana Bonfante-Mejia Susana Calle Luis Nunez-Rubiano Azin Aein Xu Zhang Amanda Jagolino-Cole Source Type: research

Neuroprotective effects of tannic acid in the postischemic brain via direct chelation of Zn < sup > 2 < /sup >
Anim Cells Syst (Seoul). 2022 Aug 19;26(4):183-191. doi: 10.1080/19768354.2022.2113915. eCollection 2022.ABSTRACTTannic acid (TA) is a polyphenolic compound that exerts protective effects under pathological conditions. The diverse mechanisms of TA can exert beneficial anti-oxidative, anti-inflammatory, and anti-cancer effects. Herein, we reported that TA affords robust neuroprotection in an animal model of stroke (transient middle cerebral artery occlusion; tMCAO) and exhibits Zn2+-chelating and anti-oxidative effects in primary cortical neurons. Following tMCAO induction, intravenous administration of TA (5 mg/kg) suppres...
Source: Cancer Control - September 1, 2022 Category: Cancer & Oncology Authors: Seung Woo Kim Da Bin Kim Hong Seok Kim Source Type: research

Renal outcomes in valve-in-valve transcatheter versus redo surgical aortic valve replacement: A systematic review and meta-analysis
CONCLUSION: Renoprotective strategies should be put into place to prevent and reduce AKI incidence regardless of the treatment modality. Patients undergoing re-intervention for the aortic valve constitute a high-risk and frail population in which ViV-TAVR demonstrated it might be a feasible option for carefully selected patients. Long-term follow-up data and randomized control trials will be needed to evaluate mortality and morbidity outcomes between these 2 treatments.PMID:36040611 | DOI:10.1111/jocs.16890
Source: Cancer Control - August 30, 2022 Category: Cancer & Oncology Authors: Arian Arjomandi Rad Vinci Naruka Robert Vardanyan Mohammad Yousuf Salmasi Panagiotis T Tasoudis Simon Kendall Roberto Casula Thanos Athanasiou Source Type: research

Lost individual income due to severe health events: life-course perspective in the Northern Finland Birth Cohort 1966
CONCLUSIONS: Stroke and heart attack but not cancer have exogenous deleterious effects on individual economy, independently of early-life factors. The effects accelerate by time. Negative income trend in control men shows that severe health events do not explain all decrease in income.PMID:36040214 | DOI:10.1093/eurpub/ckac110
Source: Cancer Control - August 30, 2022 Category: Cancer & Oncology Authors: Ina Rissanen Iiro Nerg Leena Ala-Mursula Marko Korhonen Source Type: research

Rare stroke mechanisms in 4154 consecutive patients: causes, predictors, treatment, and outcomes
CONCLUSIONS: RMS occurred in 5.3% of a large population of consecutive AISs and are most frequently related to medical interventions, cancer, and vasculitis. RMS patients have less traditional risk factors but more systemic comorbidities, hemorrhagic transformations, recurrences, and a worse long-term outcome. Identification of RMS has direct implications for early treatment and long-term outcome.PMID:35994133 | DOI:10.1007/s10072-022-06344-w
Source: Cancer Control - August 22, 2022 Category: Cancer & Oncology Authors: Alex Vicino Gaia Sirimarco Ashraf Eskandari Dimitris Lambrou Philippe Maeder Vincent Dunet Patrik Michel Source Type: research

Association between self-reported gingival bleeding and prevalent hypertension among adults in a cross-sectional study in Zhejiang province
Conclusion: Frequent gingival bleeding was positively associated with prevalent hypertension among men.PMID:35981987 | DOI:10.3760/cma.j.cn112338-20210922-00744
Source: Cancer Control - August 18, 2022 Category: Cancer & Oncology Authors: H Wang L L Chen Y Q Guan Y Cao D Shen K X Xie X Y Zhang C M Wang P Pei Y Guo M Yu L M Chen Liming Li Source Type: research