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Machine learning prediction of symptomatic intracerebral hemorrhage after stroke thrombolysis: a cross-cultural validation in Caucasian and Han Chinese cohort
CONCLUSION: The established SVM model is feasible for predicting the risk of sICH after thrombolysis quickly and efficiently in both Caucasian and Han Chinese cohort.PMID:36225969 | PMC:PMC9549180 | DOI:10.1177/17562864221129380
Source: Adv Data - October 13, 2022 Category: Epidemiology Authors: Junfeng Liu Xinyue Chen Xiaonan Guo Renjie Xu Yanan Wang Ming Liu Source Type: research

Alcohol Consumption and Stroke Risk in Men: A Population-Based Cohort Study in Rural Tianjin, China
Conclusions: These findings suggest that low-dose alcohol consumption may decrease the risk of ischemic strokes among men. Even so, the adverse effects of alcohol on the liver and pancreas cannot be ignored. Additionally, the effects of alcohol consumption on stroke risk vary with age, protecting against ischemic and total strokes among males ≥55 years old. Nevertheless, recommending light drinking and its potential health benefits should not be generalized to men of all ages.Neuroepidemiology
Source: Neuroepidemiology - June 15, 2021 Category: Epidemiology Source Type: research

Lifestyle Risk Factors and Findings on Brain Magnetic Resonance Imaging of Older Adult American Indians: The Strong Heart Study
Conclusions: This study found similar associations between smoking and vascular brain injury among American Indians, as seen in other populations. In particular, these findings support the role of smoking as a key correlate for cerebral atrophy.Neuroepidemiology
Source: Neuroepidemiology - June 4, 2019 Category: Epidemiology Source Type: research

A Population-Based Survey of Stroke Knowledge in Argentina: The SIFHON Study
Conclusions: This study represents the largest stroke awareness survey in a Spanish-speaking population. There was good recognition of some basic facts of stroke. However, the population had poor knowledge of prevalence and severity of the disease, transient ischemic attacks, and treatment availability.Neuroepidemiology
Source: Neuroepidemiology - April 15, 2019 Category: Epidemiology Source Type: research

Vascular Risk Factors and Findings on Brain MRI of Elderly Adult American Indians: The Strong Heart Study
Conclusions: This study found risk factors for cerebrovascular disease in American Indians similar to those seen in other populations and provides additional evidence for the important roles of hypertension and diabetes in promoting cerebral infarcts and brain atrophy, respectively.Neuroepidemiology 2019;52:173 –180
Source: Neuroepidemiology - January 27, 2019 Category: Epidemiology Source Type: research

Presentation, Evaluation, Management, and Outcomes of Acute Stroke in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis
Conclusions: Our review revealed the low use of evidence-based practices for acute stroke care in LMIC. The true use in hospitals that do not conduct this research is probably even lower. Strategies to evaluate and improve health system performance for acute stroke care, including implantation of stroke units and making thrombolysis more available and affordable are needed in LMIC. Registration in Prospero: CRD42017069325.Neuroepidemiology 2018;51:104 –112
Source: Neuroepidemiology - July 19, 2018 Category: Epidemiology Source Type: research

Clinico-epidemiological profile of stroke patients admitted in a tertiary care Hospital of Assam
Conclusionhaemorrhagic CVA constitutes a larger percentage of stroke subtypes on this side of the globe effecting poor to lower middle class. Proper strategy to prevent and treat haemorrhagic CVA in this part of the world is the need of the hour.
Source: Clinical Epidemiology and Global Health - July 11, 2018 Category: Epidemiology Source Type: research

Differentiating Incident from Recurrent Stroke Using Administrative Data: The Impact of Varying Lengths of Look-Back Periods on the Risk of Misclassification
Conclusion: Hospital administrative data sets linked to prior admissions can be used to distinguish recurrent from incident stroke. The risk of misclassifying recurrent stroke cases as incident events is negligible with a look-back period of 10 years.Neuroepidemiology 2017;48:111-118
Source: Neuroepidemiology - June 21, 2017 Category: Epidemiology Source Type: research

Leveraging cell type specific regulatory regions to detect SNPs associated with tissue factor pathway inhibitor plasma levels
ABSTRACT Tissue factor pathway inhibitor (TFPI) regulates the formation of intravascular blood clots, which manifest clinically as ischemic heart disease, ischemic stroke, and venous thromboembolism (VTE). TFPI plasma levels are heritable, but the genetics underlying TFPI plasma level variability are poorly understood. Herein we report the first genome‐wide association scan (GWAS) of TFPI plasma levels, conducted in 251 individuals from five extended French‐Canadian Families ascertained on VTE. To improve discovery, we also applied a hypothesis‐driven (HD) GWAS approach that prioritized single nucleotide polymorphism...
Source: Genetic Epidemiology - April 19, 2017 Category: Epidemiology Authors: Jessica Dennis, Alejandra Medina ‐Rivera, Vinh Truong, Lina Antounians, Nora Zwingerman, Giovana Carrasco, Lisa Strug, Phil Wells, David‐Alexandre Trégouët, Pierre‐Emmanuel Morange, Michael D. Wilson, France Gagnon Tags: RESEARCH ARTICLE Source Type: research

Automatic extraction of forward stroke volume using dynamic PET/CT: a dual-tracer and dual-scanner validation in patients with heart valve disease
Background: The aim of this study was to develop and validate an automated method for extracting forward stroke volume (FSV) using indicator dilution theory directly from dynamic positron emission tomography (PET) studies for two different tracers and scanners. Methods: 35 subjects underwent a dynamic 11 C-acetate PET scan on a Siemens Biograph TruePoint-64 PET/CT (scanner I). In addition, 10 subjects underwent both dynamic 15 O-water PET and 11 C-acetate PET scans on a GE Discovery-ST PET/CT (scanner II). The left ventricular (LV)-aortic time-activity curve...
Source: Epidemiologic Perspectives and Innovations - October 26, 2015 Category: Epidemiology Authors: Hendrik HarmsLars TolbodNils HanssonTanja KeroLovisa OrndahlWon KimTomas BjernerKirsten BoucheloucheHenrik WiggersJørgen FrøkiærJens Sörensen Source Type: research

Establishment of Population-Based Stroke Registry in Ludhiana City, Northwest India: Feasibility and Methodology
Conclusion: Population-based stroke registry was feasible in an urban population with the above methodology. The issues related to feasibility were identified and necessary changes were made for the main phase of the registry.Neuroepidemiology 2015;44:69-77
Source: Neuroepidemiology - March 6, 2015 Category: Epidemiology Source Type: research

Cerebral Microbleeds are associated with nocturnal reverse dipping in hypertensive patients with Ischemic stroke
Conclusion: Cerebral microbleeds are independently associated with reverse dipping on ambulatory blood pressure monitoring in hypertensive stroke patients.
Source: Epidemiologic Perspectives and Innovations - January 12, 2014 Category: Epidemiology Authors: Hyung-Min KwonJae-Sung LimYoung Seo KimJangsup MoonHyeri ParkHyun Young KimYoung-Hyo LimHyunwoo Nam Source Type: research