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The Price of Keeping the Rhythm: Increased Bleeding Risk in Patients with Atrial Fibrillation Concurrently Prescribed Amiodarone and Factor Xa Inhibitors
Atrial fibrillation is the most common sustained cardiac arrhythmia affecting nearly 2% of the population of the United States.1 Patients with atrial fibrillation are twice as likely to have a myocardial infarction and five-times as likely to have a stroke.1 Current guidelines recommend antiarrhythmic pharmacotherapy in patients with symptomatic atrial fibrillation as first-line management.2-4 Amiodarone is a very effective, and therefore, a commonly prescribed agent for this purpose.5 Anticoagulation is a key tenet in the management of atrial fibrillation due to the increased tendency of left atrial appendage clot formati...
Source: Journal of Cardiothoracic and Vascular Anesthesia - August 10, 2023 Category: Anesthesiology Authors: Nicolas Kumar, Manoj H. Iyer, Adam Dalia, Amit Bardia Tags: Editorial Source Type: research

Ischemic Stroke Management: Posthospitalization and Transition of Care
Am Fam Physician. 2023 Jul;108(1):70-77.ABSTRACTIschemic stroke is a major cause of morbidity and mortality worldwide. Ischemic stroke and transient ischemic attack exist on a continuum of the same disease process. Ischemic stroke is common, and more than 85% of stroke risk is attributed to modifiable risk factors. The initial management of acute stroke is usually performed in the emergency department and hospital settings. Family physicians have a key role in follow-up, ensuring that a complete diagnostic evaluation has been performed, addressing modifiable risk factors, facilitating rehabilitation, and managing chronic s...
Source: Pain Physician - July 13, 2023 Category: Anesthesiology Authors: Scott T Larson Brigit E Ray Jason Wilbur Source Type: research

Predicting Postoperative Atrial Fibrillation: The Search Continues
Atrial fibrillation (AF) has an incredibly large burden on the American health system with approximately 454,000 annual hospital admissions as the primary diagnosis.1 Unfortunately, AF is not a benign entity, with a reported underlying primary cause of death in 26,535 people in 2019 according to the CDC.2 AF is the cause of 1 in 7 strokes,3 and increases the risk of ischemic stroke five-fold.4 These statistics are alarming when it is considered that the incidence of postoperative atrial fibrillation (POAF) has been reported to be as high as 65% after cardiac surgery.
Source: Journal of Cardiothoracic and Vascular Anesthesia - June 12, 2022 Category: Anesthesiology Authors: Kenneth R. Hassler, Harish Ramakrishna Tags: Editorial Source Type: research

Prediction, prevention and management of new onset peri-operative atrial fibrillation and flutter in patients undergoing non-cardiac thoracic surgery: a narrative review
Minerva Anestesiol. 2022 Apr 26. doi: 10.23736/S0375-9393.21.16034-1. Online ahead of print.ABSTRACTPeri-operative atrial fibrillation and flutter (POAF) is recognized as a common complication of non-cardiac thoracic surgery. It is associated with hemodynamic instability, prolonged hospital stay, a risk of stroke and increased risk of mortality. The potential pathogenesis for POAF after non-cardiac thoracic surgery is multifactorial and not fully understood yet. Evaluation of risk factors and prediction of POAF can be beneficial for prevention and management of POAF in patients undergoing non-cardiac thoracic surgery. In t...
Source: Minerva Anestesiologica - April 27, 2022 Category: Anesthesiology Authors: Jie Liu Wuhua Ma Yankui Huang Huihui Liu Caineng Wu Source Type: research

Intraoperative echocardiographic contrast opacifies the left atrial appendage and assists in surgical exclusion
We present a man who did not tolerate anticoagulant and failed percutaneous occlusion. Intraoperative echocardiographic contrast was used to assist surgical exclusion. Follow-up showed a persistent occlusion.PMID:35075025 | DOI:10.4103/aca.ACA_192_20
Source: Annals of Cardiac Anaesthesia - January 25, 2022 Category: Anesthesiology Authors: Jeans M Santana Frank M Rosell Bhawana Dave Aimen El Manafi Source Type: research

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