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Specialty: Internal Medicine
Source: European Journal of Internal Medicine

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Total 213 results found since Jan 2013.

Safety and Tolerability of Neurohormonal Antagonism in Cardiac Amyloidosis.
CONCLUSIONS: ACEi/ARB and MRA can be safely used in CA, provided that no contraindications are present, treatment is started at a low dose and slowly up-titrated, and patients are monitored quite closely. Beta-blocker therapy is less tolerated in patients with AL amyloidosis and/or worse haemodynamic function. PMID: 32475765 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - May 27, 2020 Category: Internal Medicine Authors: Aimo A, Vergaro G, Castiglione V, Rapezzi C, Emdin M Tags: Eur J Intern Med Source Type: research

Comparison of stroke recurrence between antiplatelet and closure therapy in cryptogenic stroke patients with patent foramen ovale and its influencing factors.
PMID: 32307231 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - April 15, 2020 Category: Internal Medicine Authors: Zhang C, Zheng L, Zhang Y, Guo H, Chi J Tags: Eur J Intern Med Source Type: research

Prevalence of the age-related diseases in older patients with acquired thrombotic thrombocytopenic purpura.
CONCLUSIONS: Our findings suggest that a careful comprehensive geriatric assessment of acquired TTP patients is necessary. It is important to look for other autoimmune diseases and such age-related comorbidities as osteoporosis, arterial hypertension, ischemic heart disease and cerebrovascular disease. PMID: 32201091 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - March 18, 2020 Category: Internal Medicine Authors: Agosti P, Mancini I, Gianniello F, Bucciarelli P, Artoni A, Ferrari B, Pontiggia S, Trisolini SM, Facchini L, Carbone C, Peyvandi F, Italian Group of TTP Investigators Tags: Eur J Intern Med Source Type: research

Abnormal ankle-brachial index (ABI) predicts primary and secondary cardiovascular risk and cancer mortality.
CONCLUSIONS: The co-existence of abnormal ABI and a history of CV events identifies subjects at higher risk, who call for a more aggressive approach. Abnormal ABI is also a predictor of cancer mortality. PMID: 32151490 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - March 5, 2020 Category: Internal Medicine Authors: Visonà A, De Paoli A, Fedeli U, Tonello D, Zalunardo B, Zanatta N, Martini R, Pesavento R, Cuppini S, Prior M, Benazzi S, Cimminiello C, Avossa F Tags: Eur J Intern Med Source Type: research

Clinical outcomes and need for intensive care after non-ST-segment-elevation myocardial infarction.
CONCLUSIONS: Complications requiring ICU care were infrequent in a cohort of NSTEMI patients who were routinely admitted to the ICU over a 4-year period. The ACTION risk score had low accuracy in the prediction of complications requiring ICU care in our population. PMID: 32089424 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - February 19, 2020 Category: Internal Medicine Authors: Guimarães PO, Sampaio MC, Malafaia FL, Lopes RD, Fanaroff AC, de Barros E Silva PGM, Dos Santos TM, Okada MY, Mouallem ARE, Diniz MDS, Custódio JV, Garcia JCT, Furlan V Tags: Eur J Intern Med Source Type: research

Antithrombotic treatment in patients with atrial fibrillation undergoing coronary angioplasty: rational convincement and supporting evidence.
CONCLUSIONS: Our findings suggest that DT is safer than TT with regard to occurrence of major bleeding. DT with a direct oral anticoagulant plus clopidogrel at discharge could be effective in most patients, maintaining aspirin in periprocedural phase and as longer "tailored" treatment for patients at higher ischemic risk. PMID: 32063489 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - February 12, 2020 Category: Internal Medicine Authors: Ricottini E, Nenna A, Melfi R, Giannone S, Lusini M, Sciascio GD, Chello M, Ussia GP, Grigioni F Tags: Eur J Intern Med Source Type: research

In stroke patients, lower LDL-cholesterol is actually better.
PMID: 32037232 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - February 5, 2020 Category: Internal Medicine Authors: Castilla-Guerra L, Perez de Leon JA, Fernandez-Moreno MDC Tags: Eur J Intern Med Source Type: research

Admission glucose level was associated with increased short-term mortality and length-of-stay irrespective of diagnosis, treating medical specialty or concomitant laboratory values.
CONCLUSIONS: Short-term mortality increased substantially with admission hypo- and hyperglycemia for patients both with and without diabetes, irrespective of treating medical specialty, main discharge diagnosis, or concurrent laboratory values. Patients with diabetes (16%) were older, with higher glucose levels at admission, and with a different pattern of the association of admission glucose and mortality. PMID: 31982283 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - January 21, 2020 Category: Internal Medicine Authors: Björk M, Melin EO, Frisk T, Thunander M Tags: Eur J Intern Med Source Type: research

Mortality in patients with intracerebral hemorrhage associated with antiplatelet agents, oral anticoagulants or no antithrombotic therapy.
In conclusion, preceding treatment with antithrombotic is associated with the severity of ICH. Age, previous stroke and clinical severity at presentation were independent predictors of in-hospital death in patients with ICH. PMID: 31955918 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - January 15, 2020 Category: Internal Medicine Authors: Franco L, Paciaroni M, Enrico ML, Scoditti U, Guideri F, Chiti A, De Vito A, Terruso V, Consoli D, Vanni S, Giossi A, Manina G, Nitti C, Re R, Sacco S, Cappelli R, Beyer-Westendorf J, Pomero F, Agnelli G, Becattini C Tags: Eur J Intern Med Source Type: research

Left atrial diameter thresholds and new incident atrial fibrillation in embolic stroke of undetermined source.
CONCLUSIONS: The LAD threshold of 40 mm has the best prognostic performance among other LAD values to predict new incident AF after ESUS. The diagnostic yield of prolonged cardiac rhythm monitoring in patients with LAD ≤ 40 mm seems low; therefore, such patients may have lower priority for prolonged cardiac monitoring. PMID: 31952983 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - January 14, 2020 Category: Internal Medicine Authors: Perlepe K, Sirimarco G, Strambo D, Eskandari A, Karagkiozi E, Vemmou A, Koroboki E, Manios E, Makaritsis K, Vemmos K, Michel P, Ntaios G Tags: Eur J Intern Med Source Type: research

One-year clinical events and management of patients with atrial fibrillation hospitalized in cardiology centers: Data from the BLITZ-AF study.
CONCLUSIONS: The follow-up of the BLITZ-AF study provide an up to date picture of the clinical course of patients with AF, who appear frequently affected by heart failure and severe comorbidities which might have led to the high mortality rate. PMID: 31952984 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - January 13, 2020 Category: Internal Medicine Authors: Cemin R, Colivicchi F, Maggioni AP, Boriani G, De Luca L, Di Lenarda A, Di Pasquale G, Fabbri G, Lucci D, Gulizia MM, On the behalf of BLITZ-AF Investigators Tags: Eur J Intern Med Source Type: research

Primum non nocere does not justify clinical inertia for stroke prevention in elderly patients with atrial fibrillation in the era of direct oral anticoagulants.
PMID: 31889597 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - December 26, 2019 Category: Internal Medicine Authors: Cavallari I, Patti G Tags: Eur J Intern Med Source Type: research

Proton pump inhibitors and cardiovascular adverse effects: Real or surreal worries?
Abstract Proton pump inhibitors (PPIs) are among the most widely prescribed agents, either for treatment or prophylaxis of gastrointestinal (GI) disease, that are often administered for prolonged or chronic use. Patients with cardiovascular (CV) disease frequently receive PPIs for prophylaxis against GI bleeding due to common use of antithrombotic drugs. Over the last several years there is a growing number of reports associating chronic PPI use with a variety of serious CV and non-CV adverse effects. In this context, PPI use has been independently associated with an increased risk of CV morbidity (myocardial infa...
Source: European Journal of Internal Medicine - November 29, 2019 Category: Internal Medicine Authors: Manolis AA, Manolis TA, Melita H, Katsiki N, Manolis AS Tags: Eur J Intern Med Source Type: research

Use of proton pump inhibitors is associated with an increase in adverse cardiovascular events in patients with hemodialysis: Insight from the kids registry.
CONCLUSIONS: These results indicate that the use of PPIs in patients with maintenance hemodialysis might increase mortality and cardiovascular events without decreasing the risk of bleeding. Therefore, it should always be analyzed if a patient truly needs PPIs. PMID: 31735546 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - November 13, 2019 Category: Internal Medicine Authors: Kosedo I, Tokushige A, Takumi T, Yoshikawa A, Teraguchi K, Takenouchi K, Shiraishi K, Ikeda D, Imamura M, Sonoda T, Kanda D, Ikeda Y, Ido A, Ohishi M Tags: Eur J Intern Med Source Type: research

Diagnosis and treatment of hypertensive emergencies and urgencies among Italian emergency and intensive care departments. Results from an Italian survey: Progetto GEAR (Gestione dell'Emergenza e urgenza in ARea critica).
Abstract Hypertensive emergencies (HE) and urgencies (HU) are frequent causes of patients referral to Emergency Department (ED) and the approach may be different according to local clinical practice. Our aim was to explore awareness, management, treatment and counselling after discharge of HE and HU in Italy, by mean of an on-line survey. The young investigator research group of the Italian Society of Hypertension developed a 23-item questionnaire spread by e-mail invitation to the members of Italian Scientific societies in the field of Hypertension. 665 questionnaires were collected from EDs, Emergency and Urgenc...
Source: European Journal of Internal Medicine - November 1, 2019 Category: Internal Medicine Authors: Saladini F, Mancusi C, Bertacchini F, Spannella F, Maloberti A, Giavarini A, Rosticci M, Bruno RM, Pucci G, Grassi D, Pengo M, Muiesan ML Tags: Eur J Intern Med Source Type: research