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Effect of home-based reablement program on improving activities of daily living for patients with stroke: A pilot study
Background: Administering activities of daily living (ADL) and recovery of ADL functions are the main treatment goals in rehabilitation for patients with stroke. Reablement is one form of rehabilitative intervention, which aims to restore ADL functions performed in the community. The purpose of this study was to investigate the effects of home-based reablement from 3 concepts of ADL (ie, actual performance, ability, and self-perceived difficulty) for patients with stroke. Methods: This was a single-blind pilot randomized clinical trial. Twenty-six patients were randomly assigned into 2 groups: home-based reablem...
Source: Medicine - December 4, 2020 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research

A Stroke Occurs Every 5 Minutes in Canada A Stroke Occurs Every 5 Minutes in Canada
Findings from a recent study highlight the need for appropriate resource planning to maintain high-quality stroke care and optimize patient outcomes, said one of the researchers.Medscape Medical News
Source: Medscape Internal Medicine Headlines - January 9, 2023 Category: Internal Medicine Tags: Cardiology News Source Type: news

In acute ischemic stroke, early IV tenecteplase was noninferior to alteplase for excellent functional outcome
Ann Intern Med. 2022 Nov 1. doi: 10.7326/J22-0090. Online ahead of print.ABSTRACTMenon BK, Buck BH, Singh N, et al. Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial. Lancet. 2022;400:161-9. 35779553.PMID:36315948 | DOI:10.7326/J22-0090
Source: Annals of Internal Medicine - October 31, 2022 Category: Internal Medicine Authors: Emma Ferguson Eddy Lang Source Type: research

Prevalence and Costs of Discharge Diagnoses in Inpatient General Internal Medicine: a Multi-center Cross-sectional Study
ConclusionsGIM services care for a markedly heterogeneous population but the most common conditions were similar across 7 hospitals. The diversity of conditions cared for in GIM may be challenging for healthcare delivery and quality improvement. Initiatives that cut across individual diseases to address processes of care, patient experience, and functional outcomes may be more relevant to a greater proportion of the GIM population than disease-specific efforts.
Source: Journal of General Internal Medicine - July 27, 2018 Category: Internal Medicine Source Type: research

Fixed-dose combination antihypertensive medications, adherence, and clinical outcomes: A population-based retrospective cohort study
by Amol A. Verma, Wayne Khuu, Mina Tadrous, Tara Gomes, Muhammad M. Mamdani BackgroundThe majority of people with hypertension require more than one medication to achieve blood pressure control. Many patients are prescribed multipill antihypertensive regimens rather than single-pill fixed-dose combination (FDC) treatment. Although FDC use may improve medication adherence, the impact on patient outcomes is unclear. We compared clinical outcomes and medication adherence with FDC therapy versus multipill combination therapy in a real-world setting using linked clinical and administrative databases. Methods and findingsWe cond...
Source: PLoS Medicine - June 11, 2018 Category: Internal Medicine Authors: Amol A. Verma Source Type: research

Early versus late clinical outcomes following same day discharge after elective percutaneous coronary intervention: A systematic review and meta-analysis
Conclusions: In those patients who were discharged from the hospital on the same day following elective PCI, no significant difference was observed in the assessed early versus late clinical outcomes. However, late clinical outcomes resulted in a significantly higher rate of re-hospitalization. Larger studies should confirm this hypothesis.
Source: Medicine - January 1, 2019 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Low-Sodium Intake: A Risk Factor for Stroke?
The recent findings by Kieneker et  al1 represent the first convincing evidence that a low sodium intake might be linked to an increased cerebrovascular risk. The highly cited papers by a Canadian group2 already claimed to show a sort of J-shaped association between sodium intake and cardiovascular events, but there are limitations to these studies, as has been discussed previously.3
Source: Mayo Clinic Proceedings - March 31, 2019 Category: Internal Medicine Authors: Natale Musso, Andrea Dotto Tags: Letter to the Editor Source Type: research

Risk for Recurrent Venous Thromboembolism in Patients With Subsegmental Pulmonary Embolism Managed Without Anticoagulation : A Multicenter Prospective Cohort Study
CONCLUSION: Overall, patients with subsegmental pulmonary embolism who did not have proximal deep venous thrombosis had a higher-than-expected rate of recurrent venous thromboembolism.PRIMARY FUNDING SOURCE: Heart and Stroke Foundation of Canada and French Ministry of Health Programme Hospitalier de Recherche Clinique.PMID:34807722 | DOI:10.7326/M21-2981
Source: Annals of Internal Medicine - November 22, 2021 Category: Internal Medicine Authors: Gr égoire Le Gal Michael J Kovacs Laurent Bertoletti Francis Couturaud Carole Dennie Andrew M Hirsch Menno V Huisman Frederikus A Klok No émie Kraaijpoel Ranjeeta Mallick Amanda Pecarskie Elena Pena Penny Phillips Isabelle Pichon Tim Ramsay Marc Righini Source Type: research

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