• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Less Sodium, More Potassium, or Both: Population-wide Strategies to Prevent Hypertension
Am J Physiol Renal Physiol. 2023 Jun 1. doi: 10.1152/ajprenal.00007.2023. Online ahead of print.ABSTRACTHypertension is among the most prevalent medical conditions globally and a major contributor to chronic kidney disease, cardiovascular disease, and death. Prevention through non-pharmacologic, population-level interventions is critically needed to halt this worldwide epidemic. However, there are ongoing debates as to where public policy efforts should focus. Recently the Salt Substitute and Stroke Study demonstrated the efficacy of substituting table salt with potassium salt to reduce the risk of stroke, major cardiovasc...
Source: Am J Physiol Renal P... - June 1, 2023 Category: Urology & Nephrology Authors: Voravech Nissaisorakarn George Ormseth William Earle Martha Catalina Morales-Alvarez Swapnil Hiremath Stephen P Juraschek Source Type: research

Mechanistic and Clinical Comparison of the Erythropoietic Effects of SGLT2 Inhibitors and Prolyl Hydroxylase Inhibitors in Patients With Chronic Kidney Disease and Renal Anemia
Am J Nephrol. 2023 May 16. doi: 10.1159/000531084. Online ahead of print.ABSTRACTRenal anemia is treated with erythropoiesis-stimulating agents (ESA), even though epoietin alfa and darbepoietin increase the risk of cardiovascular death and thromboembolic events, including stroke. Hypoxia-inducible factor prolyl hydroxylase domain (HIF-PHD) inhibitors have been developed as an alternative to ESAs, producing comparable increases in hemoglobin. However, in advanced chronic kidney disease, HIF-PHD inhibitors can increase the risk of cardiovascular death, heart failure and thrombotic events to a greater extent than that with ES...
Source: American Journal of Nephrology - May 26, 2023 Category: Urology & Nephrology Authors: Milton Packer Source Type: research

Should we liberalize potassium intake in CKD? No, we should not
Although a high dietary sodium (Na) intake has dominated our understanding of pathophysiology of hypertension, the moderating effects of a dietary potassium (K) intake on blood pressure (BP) are less appreciated. K depletion in normotensive men can increase BP,1 supplementation of K among normotensive women can modestly lower 24-hour ambulatory BP,2 and in those with untreated hypertension3 or among those with hypertension and hypokalemia provoked by diuretics, K supplementation can lower BP.4 A cluster randomized trial from 600 villages in China in people with a history of previous stroke (72.6%) or a history of hypertens...
Source: Kidney International - September 20, 2022 Category: Urology & Nephrology Authors: Rajiv Agarwal Tags: Controversies in Nephrology Source Type: research

Point of care cardiac ultrasound in the management of hyponatremia: an enhancement to physical examination
AbstractAccurate assessment of fluid status is vital to appropriate management of hyponatremia. However, conventional parameters such as physical examination, vital signs, and laboratory markers such as natriuretic peptides suffer from limitations in this regard. Point of care ultrasonography (POCUS) is a noninvasive bedside diagnostic tool that is emerging as an adjunct to physical examination in internal medicine and subspecialties including nephrology. In this manuscript, we describe a complex case of hyponatremia, where stroke volume assessment using Doppler echocardiography has helped to objectively assess fluid statu...
Source: CEN Case Reports - July 5, 2021 Category: Urology & Nephrology Source Type: research

Predictors of Survival in Chronic Hemodialysis Patients: A 10-Year Longitudinal Follow-Up Analysis
CONCLUSION: In chronic hemodialysis patients, targets to improve the short-term prognosis and long-term prognosis are not equivalent. Hyperphosphatemia was a significant risk factor for the all-cause mortality among patients with normal serum albumin levels but not among patients with compromised albumin levels.PMID:33756478 | DOI:10.1159/000513951
Source: American Journal of Nephrology - March 23, 2021 Category: Urology & Nephrology Authors: Takuhiro Moromizato Kentaro Kohagura Kiyoyuki Tokuyama Yoshiki Shiohira Shigeki Toma Hajime Uehara Hisatomi Arima Shinichiro Ueda Kunitoshi Iseki Source Type: research

Pages: 1  2