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The Piano Man: A Case Report of Anterior Thalamic Infarct with Dementia and Preserved Music Ability
CONCLUSIONS: The case has implications for understanding the complex integrative functions of the thalamus, including how profound impairment can simultaneously present with cognitive strengths that may not be captured by performance on neuropsychological testing. This case also suggests that magnetic resonance imaging may be indicated in cases presenting with vascular risk factors and sudden onset cognitive impairment, given that computed tomography may not be sensitive to small subcortical infarcts.PMID:37699427 | DOI:10.1093/arclin/acad069
Source: Archives of Clinical Neuropsychology - September 12, 2023 Category: Psychiatry & Psychology Authors: Ashleigh F Parker Theone S E Paterson Tamara Goranson Jodie R Gawryluk Source Type: research

Alterations in Brain Network Organization in Adults With Obesity as Compared With Healthy-Weight Individuals and Seniors
Objective Life expectancy and obesity rates have drastically increased in recent years. An unhealthy weight is related to long-lasting medical disorders that might compromise the normal course of aging. The aim of the current study of brain connectivity patterns was to examine whether adults with obesity would show signs of premature aging, such as lower segregation, in large-scale networks. Methods Participants with obesity (n = 30, mean age = 32.8 ± 5.68 years) were compared with healthy-weight controls (n = 33, mean age = 30.9 ± 6.24 years) and senior participants who were stroke-free and without dementia (...
Source: Psychosomatic Medicine - September 1, 2021 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Carotid Artery Dissection Induced Acute Tongue Swelling in a Cocaine User.
We report a 42-year old men who presented to our observation with acute tongue swelling and atrophy of left side of tongue from a hypoglossal nerve injury. A magnetic resonance imaging revealed a denervation of the left half of the tongue from a hypoglossal nerve injury due to left extracranial internal carotid artery (ICA) dissection, without evidence of ischemic stroke. The urine toxicology screen test revealed a positivity for cocaine. This case report suggest to perform in young patient a toxicological drug screening test in presence of ICA dissection with hypoglossal nerve injury and an acute tongue swelling. However ...
Source: Psychopharmacology Bulletin - March 29, 2020 Category: Psychiatry & Psychology Tags: Psychopharmacol Bull Source Type: research

Posterior Cortical Atrophy with Right Lower Egocentric Quadrantic Neglect and Lower Vertical Allocentric Neglect.
We report a patient with probable posterior cortical atrophy who demonstrated lower right-sided quadrantic visuospatial neglect, together with allocentric vertical neglect. METHODS/RESULTS: A 68-year-old man initially noted deficits in reading and writing. Subsequently, he developed other cognitive deficits. On vertical line bisections, he deviated upward, and on horizontal line bisections, he deviated to the left. These deviations together suggest that this man's neglect might be most severe in his right (head/body-centered) lower (below eye level) visual space. When attempting to perform vertical line bisections in ...
Source: Archives of Clinical Neuropsychology - January 13, 2020 Category: Psychiatry & Psychology Authors: Tariq U, Parker A, Saadatpour L, Doty L, Heilman KM Tags: Arch Clin Neuropsychol Source Type: research

Transorbital alternating current stimulation modifies BOLD activity in healthy subjects and in a stroke patient with hemianopia: A 7 Tesla fMRI feasibility study
ConclusionsThis feasibility study showed that transorbital ACS modifies BOLD activity to visual stimulation, which outlasts the duration of the AC stimulation. This is in line with earlier neurophysiological findings of increased power in EEG recordings and functional connectivity reorganization in patients with impaired vision. Accordingly, the larger BOLD response area after stimulation can be explained by more coherent activation and lower variability in the activation. Alternatively, increased neuronal activity can also be taken into account. Controlled trials are needed to systematically evaluate the potential of repe...
Source: International Journal of Psychophysiology - April 11, 2019 Category: Psychiatry & Psychology Source Type: research

Differential Associations of Socioeconomic Status With Global Brain Volumes and White Matter Lesions in African American and White Adults: the HANDLS SCAN Study
Objective: The aim of the study was to examine interactive relations of race and socioeconomic status (SES) to magnetic resonance imaging (MRI)–assessed global brain outcomes with previously demonstrated prognostic significance for stroke, dementia, and mortality. Methods: Participants were 147 African Americans (AAs) and whites (ages 33–71 years; 43% AA; 56% female; 26% below poverty) in the Healthy Aging in Neighborhoods of Diversity across the Life Span SCAN substudy. Cranial MRI was conducted using a 3.0 T unit. White matter (WM) lesion volumes and total brain, gray matter, and WM volumes were computed. An SES com...
Source: Psychosomatic Medicine - April 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research