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Specialty: Primary Care
Source: Maturitas
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Total 60 results found since Jan 2013.
The comparative effect of exercise interventions on balance in perimenopausal and early postmenopausal women: A systematic review and network meta-analysis of randomised, controlled trials
Menopause is associated with a range of physiological, psychological and social implications [1,2]. Changes in endocrine function have also been related to higher risks for cardiovascular disease, stroke and osteoporosis [3 –5]. Furthermore, an earlier age of menopause onset is related to greater frailty in later life [6].
Source: Maturitas - June 15, 2023 Category: Primary Care Authors: Gregory S. Walsh, Anne Delextrat, Adam Bibbey Tags: Review article Source Type: research
Hair sodium concentration is a predictive factor for incident hypertension in middle aged and older Korean adults
Hypertension is associated with high morbidity and mortality from cardiovascular diseases and stroke. High sodium intake is known to contribute to high rates of high blood pressure and its sequalae. However, it is not well known whether sodium in tissue is associated with hypertension development. We investigated the association between sodium amount assessed by hair mineral analyses and incident hypertension for median 4.2 years follow-up.
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Young-Sang Kim, Han Jin Oh, Byung Yeon Yu, Kunhee Han Tags: Abstract ID: 108 Source Type: research
Menopause, lipids and cardiovascular risk
The greatest mortality burden for women in Europe is due to cardiovascular diseases (CVD), such as stroke and coronary heart disease. Women develop CVD on average 10 years later than men. Premenopausal women have a more favorable CVD risk factor profile characterized by lower cholesterol levels and blood pressure and a lower prevalence of diabetes. During the transition to menopause, women experience changes in phenotype and metabolism associated with an increased risk of CVD; including increase in abdominal fat, increase in low-density lipoprotein-cholesterol (LDLC) and systolic blood pressure, and increased insulin resistance.
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Jeanine Roeters van Lennep Tags: Abstract ID: 44 Source Type: research
The association between arterial hypertension and menarcheal age
Arterial hypertension (AHTN) is considered the most important risk factor for cardiovascular disease (CVD) and premature death. In low-income and middle-income countries, about 50 % of stroke and ischemic heart disease incidents and approximately 7.6 million deaths are secondary to AHTN [1,2]. It is not only highly prevalent but is still rapidly growing; as a result, studies estimate that by 2025 its prevalence will reach>29 % [3]. Research in Iran (2011) illustrated that the prevalence of AHTN and pre-hypertension is 25.6 % and 39.8 % in adults aged 25–70 years, respectively [4].
Source: Maturitas - May 3, 2023 Category: Primary Care Authors: Maryam Farahmand, Maryam Mousavi, Amir Abbas Momenan, Fereidoun Azizi, Fahimeh Ramezani Tehrani Tags: Original article Source Type: research
Hypertension across a woman's lifespan
Hypertension is recognized globally as the leading risk factor for cardiovascular disease morbidity and mortality in women, and considered their “most substantial and neglected health burden” in a recent publication by the Lancet women and cardiovascular disease Commission [1]. Over half of women aged over 55 years of age in the United States are affected by hypertension [2], which represents the most common modifiable risk factor of c ardiovascular disease, including myocardial infarction and stroke [3].
Source: Maturitas - December 6, 2022 Category: Primary Care Authors: Tara D'Ignazio, Sophie Grand'Maison, Lyne B érubé, Jessica Forcillo, Christine Pacheco Tags: Review article Source Type: research
The effect of menopausal hormone therapy on the risk of melanoma and keratinocyte skin cancer: A systematic review and meta-analysis of observational studies
The re-analysis of Women's Health Initiative and the publication of data emerging from recent clinical trials data have restored the initial decline in the use of menopausal hormone therapy (MHT), due to adverse events, such as stroke and pulmonary embolism [1,2]. Nowadays, an increasing number of women treat their menopausal symptoms with hormonal therapies, which exhibit a better safety profile. However, the association of MHT with cancer development remains a potent drawback, with breast and endometrial cancer being the most frequently reported neoplasms [3,4].
Source: Maturitas - November 4, 2022 Category: Primary Care Authors: Konstantinos Lallas, Panagiotis Anagnostis, Patroklos Theocharis, Eirini Boureka, Athanasios Kyrgidis, Eleftherios Klonos, Georgios Papazisis, Zoe Apalla, Aimilios Lallas, Efstratios Vakirlis Tags: Review article Source Type: research
Mammography biomarkers of cardiovascular and musculoskeletal health: A review
Cardiovascular disease (CVD) represents the leading cause of mortality and morbidity in both women and men and constitutes a major health and economic burden for healthcare systems all over the world [1]. In Europe, 47 % of all deaths in females are caused by CVD: ischemic heart disease and stroke account for 38 % and 26 % of all CVD deaths, respectively [1]. Indeed, estrogen has a protective role against CVD during the fertile age [2], this protection however tends to vanish during the menopause transition , thus contributing to increase CVD risk, together with other adverse physiological and metabolic changes occu...
Source: Maturitas - October 19, 2022 Category: Primary Care Authors: Veronica Magni, Davide Capra, Andrea Cozzi, Caterina B. Monti, Nazanin Mobini, Anna Colarieti, Francesco Sardanelli Tags: Review Source Type: research
The association between grip strength and incident carotid atherosclerosis in middle-aged and older adults: The TCLSIH cohort study
Carotid atherosclerosis (CAS) is a multifactorial and complex chronic inflammatory disease in the cervical arteries [1]. Several studies have documented that patients with CAS have increased risk of stroke and other major cardiovascular events [2]. In 2014 the prevalence of stroke in China was 2.06 % [3], and in 2017 an estimated 31 % of deaths globally were from cardiovascular disease (CVD) [4]. Carotid plaque and carotid intima-media thickness (CIMT) have been proposed as surrogate markers of CAS [5].
Source: Maturitas - September 29, 2022 Category: Primary Care Authors: Bei Zhang, Xuena Wang, Yeqing Gu, Qing Zhang, Li Liu, Ge Meng, Hongmei Wu, Shunming Zhang, Tingjing Zhang, Huiping Li, Juanjuan Zhang, Shaomei Sun, Xing Wang, Ming Zhou, Qiyu Jia, Kun Song, Jian Huang, Junsheng Huo, Bing Zhang, Gangqiang Ding, Kaijun Niu Tags: Original article Source Type: research
Wishing to die or self-harm after stroke: A planned secondary analysis of the AFFINITY Randomised Controlled Trial
Stroke is associated with adverse health outcomes, including self-harm [1]. Strokes double the risk of suicide attempts and increase the risk of death by suicide, although the quality of available evidence is low [2]. Suicide acts are commonly preceded by suicidal thoughts, although available studies have often relied on the use of administrative data, chart reviews, or one-off assessments of suicide ideation [2]. There is also uncertainty about whether the use of antidepressants after a stroke reduces the prevalence of post-stroke suicidal thoughts.
Source: Maturitas - August 31, 2022 Category: Primary Care Authors: Osvaldo P. Almeida, Graeme J. Hankey, Andrew Ford, Christopher Etherton-Beer, Leon Flicker, Maree Hackett, AFFINITY Trial Collaboration Tags: Short communication Source Type: research
Psychological and social health outcomes of physical activity around menopause: A scoping review of research
Menopause is generally defined as the permanent cessation of menstruation and is usually categorized into premenopausal, perimenopausal and postmenopausal stages, defined on the basis of endocrine status and regularity of menstrual bleeding pattern [1]. Physiological research has shown that endocrine changes related to menopause involve a higher risk of several forms of cardiovascular disease, such as heart attack, stroke and atherosclerosis, as well as osteoporosis [2].
Source: Maturitas - August 3, 2022 Category: Primary Care Authors: Maria Hybholt Tags: Review article Source Type: research
Menopausal hormone therapy with conjugated equine estrogen is associated with a higher risk of hemorrhagic stroke than therapy with estradiol: a retrospective population-based cohort study
Estrogen therapy is prescribed for women without a uterus. For women with intact uteri, progestogens should be added to protect against endometrial hyperplasia. Different estrogen profiles may cause different side effects and beneficial clinical outcomes [1]. Different forms of estrogen also have different serum E2 concentrations; a previous study demonstrated that 1 mg E2 was equivalent to 0.4 mg CEE [1]. Progestin includes medroxyprogesterone acetate (MPA) and norethindrone acetate (NE). In Taiwan, the most common MHT for patients with an intact uterus are CEE (0.625 mg) or E2 (2 mg) combined with 5 mg MPA or 1 mg NE [2,3].
Source: Maturitas - August 1, 2022 Category: Primary Care Authors: Wei-Chuan Chang, Jen-Hung Wang, Dah-Ching Ding Tags: Original article Source Type: research
Ketogenic therapy for Parkinson's disease: A systematic review and synthesis without meta-analysis of animal and human trials
Parkinson's disease (PD) is a neurodegenerative disorder manifesting a progressive loss of dopaminergic neurons in the substantia nigra pars compacta (SNc) and the subsequent development of dystrophic striatal projections to the putamen [1]. Approximately 1.6 % of Americans over the age of 65 have a PD diagnosis [2], similar to the rate of stroke or the prevalence of migraine. A pathological hallmark of the disease is the presence of Lewy bodies, intracellular protein aggregates with a high composition of α-synuclein [3].
Source: Maturitas - June 9, 2022 Category: Primary Care Authors: Maria G. Grammatikopoulou, Georgios Tousinas, Chrysanthi Balodimou, Dimitrios A. Anastasilakis, Konstantinos Gkiouras, Efthimios Dardiotis, Athanasios E. Evangeliou, Dimitrios P. Bogdanos, Dimitrios G. Goulis Tags: Original article Source Type: research
Adjuvant therapy with traditional Chinese medicine and long-term mortality in patients with stroke: a nationwide population-based cohort study in Taiwan
Stroke has remained the second leading cause of death and disability-adjusted life-years worldwide [1]. The number of disability-adjusted life-years, deaths, and stroke survivors has continued to increase since the past decade [2]. Neurological and medical complications after stroke can lead to short-term and long-term comorbidity and mortality, and increased medical costs [3]. The economic and healthcare burden of stroke remains a critical issue globally in an aging society.
Source: Maturitas - December 10, 2021 Category: Primary Care Authors: Chung-Yen Lu, Shu-Ru Lee, Chee-Jen Chang, Pei-Chun Chen Source Type: research
Patterns of physical activity and sedentary behavior and their associated factors among nondisabled stroke survivors
Stroke is a leading cause of mortality and long-term disabilities, with increasing prevalence worldwide despite a decreased mortality rate [1]. Risk factor reduction and pharmacological treatment are necessary to prevent stroke and decrease the disease burden. Insufficient physical activity (PA) and a sedentary behavior (SB) are well-known independent risk factors for stroke [2]. Considering the decrease in PA along with aging [3], there is a growing concern that older stroke survivors may be at a higher risk of physical inactivity [4].
Source: Maturitas - November 12, 2021 Category: Primary Care Authors: Young-Ah Choi, Jung Soo Lee, Jae Hyeon Park, Yeo Hyung Kim Tags: Original Article Source Type: research
Handgrip strength as a predictor of incident hypertension in the middle-aged and older population: The TCLSIH cohort study
Hypertension remains one of the most important and modifiable risk factors for disease and death worldwide [1]. Hypertension is related to multiple cardiovascular and renal outcomes, including coronary heart disease, stroke, peripheral vascular disease, cognitive impairment, renal impairment, and visual impairment [2-4]. Cardiovascular diseases (CVD) are responsible for almost 17 million deaths worldwide, with hypertension accounting for 55% [5]. The global prevalence of hypertension is rapidly increasing due to an ageing population, urbanization and associated lifestyle changes.
Source: Maturitas - June 10, 2021 Category: Primary Care Authors: Yeqing Gu, Jun Dong, Ge Meng, Qing Zhang, Li Liu, Hongmei Wu, Shunming Zhang, Yawen Wang, Tingjing Zhang, Xuena Wang, Shaomei Sun, Xing Wang, Qiyu Jia, Kun Song, Qiang Liu, Kaijun Niu Source Type: research
