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Specialty: Pediatrics

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Total 733 results found since Jan 2013.

Moving Toward a New Standard of Care for Acute Pediatric Stroke
This article summarizes the issues and presentations behind identifying acute pediatric stroke, the research behind these emerging therapies in children, and the process of successfully applying pediatric stroke protocols. [Pediatr Ann. 2021;50(6):e242-e244.].PMID:34115557 | DOI:10.3928/19382359-20210519-01
Source: Pediatric Annals - June 11, 2021 Category: Pediatrics Authors: Henry David Source Type: research

Challenges of implementation of the RCPCH paediatric stroke guidelines (acute management component) and how they can be overcome
In August 2017, the Royal College of Paediatric and Child Health (RCPCH) published guidelines for the management of stroke in childhood between 1 month and 18 years of age (see hyperlink). This comprehensive 169-page publication is a National Institute for Health and Care Excellence (NICE)-accredited multiprofessional evidence-based guideline that provides recommendations for the management of stroke in children and young people. A small proportion of the guideline focuses on acute ischaemic stroke management with thrombolysis. Only a small number of children will be eligible for consideration for thrombolysis; however, it...
Source: Archives of Disease in Childhood - June 17, 2022 Category: Pediatrics Authors: Byrne, S., Ram, D. Tags: Review Source Type: research

Current management of post-varicella stroke in children: A literature review.
Abstract Among infectious factors, varicella-zoster virus (VZV) is a leading cause of central nervous system vasculopathy and stroke in childhood. Not only have viral markers been detected in the cerebrospinal fluid of affected patients, but also direct evidence of viral particles in the wall of cerebral arteries has been demonstrated in rare pathological specimens. This certainly reflects a localized infectious process likely associated with variable indirect inflammatory responses. Yet the usefulness in this setting of a lumbar puncture as well as of subsequent targeted antiviral and/or anti-inflammatory therapi...
Source: Archives de Pediatrie - July 6, 2013 Category: Pediatrics Authors: Monteventi O, Chabrier S, Fluss J Tags: Arch Pediatr Source Type: research

Malignant Paraganglioma Presenting With Hemorrhagic Stroke in a Child
We report here the case of a 12-year-old boy with malignant sympathetic paraganglioma presenting with hemorrhagic stroke. Severe hypertension was found and the patient evolved into a coma. Brain computed tomography scan showed right thalamus hemorrhage with intraventricular extension. After clinical improvement, further investigation revealed elevated catecholamine and metanephrine levels, and 2 abdominal tumors were identified by computed tomography. Resection of both lesions was performed, and histologic findings were consistent with paraganglioma. Multiple metastatic involvement of bones and soft tissues appeared severa...
Source: PEDIATRICS - December 2, 2013 Category: Pediatrics Authors: Luiz, H. V., da Silva, T. N., Pereira, B. D., Santos, J. G., Goncalves, D., Manita, I., Portugal, J. Tags: Case Report Source Type: research

Feasibility and Safety of Erythropoietin for Neuroprotection after Perinatal Arterial Ischemic Stroke
Conclusions: rhEPO in neonates with perinatal arterial ischemic stroke had no adverse effects on red blood cells, white blood cells, platelets counts, or coagulation. rhEPO, 3000 IU/kg in total, given during a 3-day period, appears to be a safe therapy. The beneficial effects remains to be demonstrated in a larger, randomized, double-blind, placebo-controlled trial.
Source: The Journal of Pediatrics - December 9, 2013 Category: Pediatrics Authors: Manon J. Benders, Niek E. van der Aa, Maurice Roks, Henrica L. van Straaten, Ivana Isgum, Max A. Viergever, Floris Groenendaal, Linda S. de Vries, Frank van Bel Tags: Original Articles Source Type: research

Hyperbaric oxygen for neurologic indications. Action plan for multicenter trials in: stroke, traumatic brain injury, radiation encephalopathy and status migrainosus
Publication date: September–October 2012 Source:Pediatria Polska, Volume 87, Issue 5 Author(s): Harry T. Whelan , Ann K. Helms Introduction: There is great interest in using hyperbaric oxygen (HBO) to treat neurological disease. The exquisite sensitivity of neural tissue to hypoxia makes increased oxygenation attractive as a therapy for disease processes that induce ischemia, edema, and, more recently, apoptosis. Four things specifically exist as targets for future projects and clinical trials: (1) stroke (2) traumatic brain injury (3) radiation induced necrosis and (4) status migrainosus. Methods: Specific aims: Strok...
Source: Pediatria Polska - November 6, 2014 Category: Pediatrics Source Type: research