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No effect of calcium and vitamin D intake on maternal blood pressure in a healthy pregnant population
Pregnancy causes physiological changes in blood pressure (BP). In patients without pre-existing hypertension, BP falls during the first half of pregnancy and rises from 34 weeks onwards [1]. Hypertensive disorders in pregnancy (HDP) complicate approximately 10% of pregnancies and are associated with adverse outcomes for both mother and foetus [2]. Women with a history of HDP are also at increased risk of developing hypertension in later life as well as ischaemic heart disease, stroke and renal disease [3].
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 6, 2021 Category: OBGYN Authors: Hannah Forde, Rachel K. Crowley, Malachi J. McKenna, Mark T. Kilbane, Marie Conway, Ciara M. McDonnell, Patrick J. Twomey, Fionnuala M. McAuliffe Tags: Full length article Source Type: research

Pharmacist ’s knowledge regarding the management of overactive bladder in elderly women
Anticholinergic drugs used to treat overactive bladder (OAB), have common side effects, including constipation, dry eyes and dry mouth. They can also cause central nervous system effects such as confusion and reduction in cognitive function [1]. Polypharmacy and an increase in blood brain barrier permeability increase these effects [2] which, are more likely in the elderly [3] as aging, as well as trauma, multiple sclerosis, hypertension, stroke and diabetes [4], leads to increased blood brain barrier permeability.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 16, 2021 Category: OBGYN Authors: George Araklitis, Angie Rantell, Georgina Baines, Richard Flint, Dudley Robinson, Linda Cardozo Tags: Full length article Source Type: research

Hydrouretonephrosis caused by uterine prolapse after gellhorn pessary displacement
we report a case of acute renal failure and urosepsis due to bilateral ureteral obstruction in a patient with a displaced pessary. The patient was a 77-year-old woman with ischemic heart disease and stroke induced hemiplegia. Her procidentia was successfully treated for many years with a 3.25 ″ Gellhorn pessary indicated for impossibility to retain a ring [1]. Previous ultrasound of kidneys did not demonstrate any hydronephrosis. A few days after the last outpatient visit for pessary change she was referred to the emergency room with fever and voiding difficulties.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - December 10, 2020 Category: OBGYN Authors: Marta Barba, Luca Locatelli, Stefania Palmieri, Alice Cola, Stefano Manodoro, Matteo Frigerio Tags: Short communication Source Type: research

Markers of maternal cardiac dysfunction in pre-eclampsia and superimposed pre-eclampsia
Women who experience hypertensive disorders of pregnancy have an increased risk of developing cardiovascular diseases including hypertension, stroke, and ischaemic heart disease later in life.1 –3 This risk is evident shortly after an affected pregnancy and persists for decades.4 The mechanism underlying this association is not known, particularly whether women who develop hypertensive disorders are at higher risk pre-pregnancy and pregnancy unmasks their cardiovascular risk, or whether hypertensive disorders of pregnancy are an index event causing cardiovascular damage.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 18, 2019 Category: OBGYN Authors: Frances Conti-Ramsden, Carolyn Gill, Paul T. Seed, Kate Bramham, Lucy C. Chappell, Fergus P. McCarthy Tags: Full length article Source Type: research

Stroke recurrence in pregnancy: Experience at a regional referral center
Although stroke is more common with advancing age, especially in the elderly, women of reproductive age may still suffer from stroke, and from its deleterious consequences. Women of reproductive age who suffer a stroke may do so either due to a specific predisposition, or due to pregnancy-related hypertensive emergencies.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 11, 2019 Category: OBGYN Authors: Adeeb Khalifeh, Andrea Berghella, Sindy Moreno, Kathryn Corelli, Emily Leubner, Gabriele Saccone, Badih Daou, Pascal Jabbour Source Type: research

Cerebellar stroke in pregnancy
Introduction: Gestational cerebral vascular ischaemia is a rare diagnosis affecting about 4 per 100,000 deliveries. It is commonest during the third trimester and in the puerperium. Cerebellar stroke accounts for 2% of all strokes during pregnancy.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 19, 2019 Category: OBGYN Authors: Theresia Dalli, Silvaine Dalli, Luke Saliba, Joshua Smith, Isabelle Saliba Tags: Movies Case Reports 2 – PPH, Puerperium and Neurology Source Type: research

Accidental ultrasound detection of Galen vein aneurysm at term pregnancy
Introduction: Galen vein aneurysm is the most common congenital arteriovenous (AV) malformation. It consists of an arteriovenous shunt dilating vascular bed. Brain structures of the posterior cranial fossa are often compressed by this dilatation. The most often manifestations are ischemic changes of neonatal brain as a stroke, steal phenomenon, hydrocephalus or heart failure.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 19, 2019 Category: OBGYN Authors: Eva Matejkov á, Marie Raszyková, Michaela Bukovanská, David Matura, Erika Doležálková, Richard Špacek, Ondrej Šimetka Tags: Movies Case Reports 2 – PPH, Puerperium and Neurology Source Type: research

Diagnostic of rare form of acute stroke (venous stroke) in early postpartum period
Introduction: Venous stroke (VS) is a rare form of acute ischemic stroke as a thrombosis of Trolard vein (the frequency 0.1% to 3 –5%) occurs when the outflow of blood from the superficial cortical veins of the brain along the large anastomotic vein of Trolard and the small anastomotic vein of Labbe in turn, flow into the large vein of Gallen, which collects blood from the deep cerebral veins and falls into a straight sinus. Verification of VS is difficult due to the following features: the defeat of the parieto-occipital region gives meagre focal neurologic symptoms and more pronounced cerebral symptoms.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 19, 2019 Category: OBGYN Authors: Nataliia Chemer, Nadiia Ruda, Andrii Tkachenko Tags: Movies Case Reports 2 – PPH, Puerperium and Neurology Source Type: research

Congenital thrombocytopenia, intractable menorrhagia at menarche and Ischemic stroke
We present a rare case of severe intractable menorrhagia occurring with the first period in a 12-year-old girl who has a positive family history of bleeding disorder. She presented with a series of challenges in terms of diagnosis, management, and therapy.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 19, 2019 Category: OBGYN Authors: Manal Taha, Olubunmi Oniya Tags: Session 18 – Complications and cases gone wrong Source Type: research

Stroke after Pregnancy Disorders
Women with hypertensive pregnancy disorders are at risk of developing stroke, possibly mediated by female-specific risk factors. Pregnancy is considered to be a stress test for cardiovascular health later in life [1]. In the current study we assessed the occurrence of pregnancy disorders, among women with a history of ischemic stroke who participated in the Dutch acute stroke study (DUST) and related these risk factors to age of stroke onset, stroke subtype, radiological characteristics and clinical outcome.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - June 9, 2017 Category: OBGYN Authors: Gerbrand A. Zoet, Katie M. Linstra, Marie Louise E. Bernsen, Maria P.H. Koster, Irene C. van der Schaaf, L. Jaap Kappelle, Bas B. van Rijn, Arie Franx, Marieke J.H. Wermer, Birgitta K. Velthuis, on behalf of the DUST investigators Tags: Letter to the Editor Source Type: research

Maternal death from stroke: a thirty year national retrospective review
Conclusion: This is the largest UK study examining the incidence of fatal maternal stroke in pregnancy and the puerperium. Our results highlight the high proportion of women who die from stroke in the puerperium. Sub-standard care featured especially in regard to management of dangerously high systolic blood pressure levels. These deaths highlight the importance of education in managing rapid-onset hypertension and superimposed coagulopathies.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - October 7, 2013 Category: OBGYN Authors: Lin Foo, Susan Bewley, Anthony Rudd Tags: Obstetrics and Maternal-Fetal Medicine Source Type: research