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The association of adult vaccination with the risk of cerebrovascular ischemia: A systematic review and meta-analysis
There is mounting evidence supporting infection as an independent risk factor for ischemic stroke (IS), while preliminary data indicate that vaccination may prevent IS. We performed a systematic review and meta-analysis of available randomized clinical trials (RCTs) or prospective observational cohorts reporting associations of influenza vaccination (IV) and/or pneumococcal vaccination (PV) with IS. We identified a total of 12 studies (543,311 patients; 47.4% vaccinated). Vaccination was not related to the risk of IS (RR=1.06, 95%CI: 0.74 –1.51, p=0.77), with no significant differences (p=0.26) among RCTs (RR=0.66, 95%CI...
Source: Journal of the Neurological Sciences - January 8, 2018 Category: Neurology Authors: Georgios Tsivgoulis, Aristeidis H. Katsanos, Ramin Zand, Muhammad Fawad Ishfaq, Muhammad Taimur Malik, Theodore Karapanayiotides, Konstantinos Voumvourakis, Sotirios Tsiodras, John Parissis Source Type: research

Evaluating Clinical Effectiveness of Pneumococcal Vaccination in Preventing Stroke: The CAPAMIS Study, 3-Year Follow-up
This study assessed clinical effectiveness of PPV23 in preventing ischemic stroke in people older than 60 years.Methods: We conducted a population-based cohort study involving 27,204 individuals of 60 years or older in Tarragona, Spain, who were prospectively followed from December 01, 2008, until November 30, 2011. Outcomes were neuroimaging-confirmed ischemic stroke, 30-day mortality from stroke, and all-cause death. Pneumococcal vaccination effectiveness was evaluated by Cox regression analyses, estimating hazard ratios (HRs) adjusted for age, sex, comorbidities, and influenza vaccine status.Results: Cohort members were...
Source: Journal of Stroke and Cerebrovascular Diseases - March 21, 2014 Category: Neurology Authors: Angel Vila-Corcoles, Olga Ochoa-Gondar, Teresa Rodriguez-Blanco, Cinta de Diego-Cabanes, Eva Satue-Gracia, Angel Vila-Rovira, Cristina Torrente Fraga, EPIVAC Research Group Tags: Original Articles Source Type: research