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Statins may Decrease Aneurysm wall Enhancement of Unruptured Fusiform Intracranial Aneurysms: A high-resolution 3T MRI Study
AbstractInflammation plays an integral role in the formation, growth, and progression to rupture of unruptured intracranial aneurysms. Aneurysm wall enhancement (AWE) in high-resolution magnetic resonance imaging (HR-MRI) has emerged as a surrogate biomarker of vessel wall inflammation and unruptured intracranial aneurysm instability. We investigated the correlation between anti-inflammatory drug use and three-dimensional AWE of fusiform intracranial aneurysms (FIAs). We retrospectively analyzed consecutive patients with FIAs in our database who underwent 3T HR-MRI at three Chinese centers. FIAs were classified as fusiform...
Source: Translational Stroke Research - September 7, 2023 Category: Neurology Source Type: research

Association of remnant cholesterol with intracranial atherosclerosis in community-based population: The ARIC study
Intracranial atherosclerotic stenosis (ICAS) is one of the main prevalent causes of ischemic stroke globally.1,2 However, even with aggressive medical management, the annual rate of stroke recurrence remains high among individuals with multiple risk factors and severe stenosis.2 Moreover, ICAS has been connected to an elevated risk of mild cognitive impairment and dementia3, which confers an extra necessity for the identification of risk factors associated with ICAS.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2023 Category: Neurology Authors: Peng Zhang, Ziheng Zhang, Daojing Li, Rongrong Han, Hongfang Li, Jinfeng Ma, Peng Xu, Ziyou Qi, Lixia Liu, Aimei Zhang Source Type: research

Monitoring Risk and Preventing Ischemic Stroke in the Very Old
This article examines current guidelines and evidence regarding medical management, lifestyle changes, and psychosocial interactions that can contribute to the primary and secondary prevention of ischemic stroke in the very old.AREAS COVERED: The authors conducted a literature search for ischemic stroke prevention and risk assessment in the elderly via PubMed. Furthermore, they describe current strategies for monitoring risk and preventing ischemic stroke in the elderly population.EXPERT OPINION: Ischemic stroke poses a significant health risk to the elderly, with prevention relying on managing modifiable risk factors such...
Source: Expert Review of Neurotherapeutics - August 4, 2023 Category: Neurology Authors: Mychael Delgardo Grant Rubin Thilan Tudor Anthony J Tang Geoffrey Reeves E Sander Connolly Source Type: research

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