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As some hail new antibody treatment for Alzheimer ’s, safety and benefit questions persist
In a packed San Francisco conference room with a celebratory atmosphere, upbeat company representatives and scientists yesterday presented detailed clinical trial data on the first Alzheimer’s treatment shown to clearly, albeit modestly, slow the disease’s normal cognitive decline. The antibody therapy has buoyed a field marked by decades of failures. Now, it appears to be on the cusp of being greenlit by the U.S. Food and Drug Administration (FDA). Yet other researchers warn of potential risks, including brain swelling and brain hemorrhages that were linked to the recently disclosed deaths of two trial participants wh...
Source: Science of Aging Knowledge Environment - December 1, 2022 Category: Geriatrics Source Type: research

The Relationship between Dental Findings and Tongue Pressure: A Survey of 745 Community-Dwelling Adults and Elderly Persons in Japan
Conclusion: Tooth loss was significantly associated with lower tongue pressure. It was suggested that fixed prosthesis treatment might prevent the reduction of tongue pressure, but removable dentures did not have such an effect.Gerontology
Source: Gerontology - February 17, 2021 Category: Geriatrics Source Type: research

Relationship between Sarcopenia and Swallowing Capacity in Community-Dwelling Older Women
Conclusions: We found that sarcopenia was related to the swallowing capacity in older women in this study. Future research should clarify whether a similar relationship exists in older men as well as the effect of sarcopenia on the swallowing capacity in older adults over a period of time.Gerontology
Source: Gerontology - October 19, 2020 Category: Geriatrics Source Type: research

Role of potentially inappropriate medication use in rehabilitation outcomes for geriatric patients after strokes
ConclusionIncreased PIM use during hospitalization might be a predictor of reduced functional improvement in geriatric patients after strokes. Geriatr Gerontol Int 2017; ••: ••–••.
Source: Geriatrics and Gerontology International - September 1, 2017 Category: Geriatrics Authors: Eiji Kose, Toshiyuki Hirai, Toshiichi Seki, Hiroyuki Hayashi Tags: Original Article: Epidemiology, Clinical Practice and Health Source Type: research

Heterogeneity in 14-year Dementia Incidence Between Asian American Subgroups
Conclusions: Future studies are needed to understand how immigration history, social, environmental, and genetic factors contribute to dementia risk in the growing and diverse Asian American population.
Source: Alzheimer Disease and Associated Disorders - July 1, 2017 Category: Geriatrics Tags: Original Articles Source Type: research