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Specialty: Neurosurgery

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Total 6508 results found since Jan 2013.

Stroke paradox with SGLT-2 inhibitors: a play of chance or a viscosity-mediated reality?
Diabetes mellitus is a major risk factor for cardiovascular morbidity and mortality. Current therapeutic strategies have not provided constant beneficial cardiovascular-related results. Sodium–glucose co-transporters 2 (SGLT-2) inhibitors have emerged as a novel antidiabetic class of drugs that exert favourable results in a variety of other cardiovascular risk factors too, such as increased blood pressure and body weight. The Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes (EMPA-REG OUTCOME) study was the first trial that evaluated cardiovascular outcomes in patients with diabetes with the us...
Source: Journal of Neurology, Neurosurgery and Psychiatry - February 16, 2017 Category: Neurosurgery Authors: Imprialos, K. P., Boutari, C., Stavropoulos, K., Doumas, M., Karagiannis, A. I. Tags: Stroke, Hypertension Cerebrovascular disease Source Type: research

Proteinuria as an independent risk factor for contrast-induced acute kidney injury and mortality in patients with stroke undergoing cerebral angiography
Conclusions Proteinuria is an independent risk factor for CI-AKI and 1-year mortality in patients with stroke undergoing cerebral angiography. More attention should be paid to the development of CI-AKI in patients with stroke with proteinuria.
Source: Journal of NeuroInterventional Surgery - April 13, 2017 Category: Neurosurgery Authors: Tao, Y., Dong, W., Li, Z., Chen, Y., Liang, H., Li, R., Mo, L., Xu, L., Liu, S., Shi, W., Zhang, L., Liang, X. Tags: Open access, Ischemic stroke Source Type: research

Predictors of false-positive stroke thrombectomy transfers
Conclusions Clinical scales appear to overdiagnose LVO and may be responsible for the majority of our stroke code transfers not undergoing thrombectomy. Primary stroke centres therefore have reason to develop the capability to rapidly acquire and interpret a CTA in patients with suspected LVO prior to transfer. Such efforts may reduce the costs associated with unnecessary thrombectomy transfers.
Source: Journal of NeuroInterventional Surgery - August 17, 2017 Category: Neurosurgery Authors: Yi, J., Zielinski, D., Ouyang, B., Conners, J., Dafer, R., Chen, M. Tags: Editor''s choice, Ischemic stroke Source Type: research

Ultra-distal access of the M1 segment with the 5 Fr Navien distal access catheter in acute (anterior circulation) stroke: is it safe and efficient?
Conclusions Ultra-distal placement of the Navien 58 distal access catheter into the M1 segment in acute anterior circulation stroke can be achieved consistently, is safe in practice, and results in good recanalization success rates.
Source: Journal of NeuroInterventional Surgery - June 16, 2017 Category: Neurosurgery Authors: Janssen, H., Killer-Oberpfalzer, M., Patzig, M., Buchholz, G., Lutz, J. Tags: Ischemic stroke Source Type: research

Optimal thresholds to predict long-term outcome after complete endovascular recanalization in acute anterior ischemic stroke
Conclusions After complete recanalization in acute anterior circulation ischemic stroke, a good long-term outcome could be accurately predicted reaching NIHSS score ≤5 after 24 hours.
Source: Journal of NeuroInterventional Surgery - November 18, 2021 Category: Neurosurgery Authors: Neuberger, U., Vollmuth, P., Nagel, S., Schönenberger, S., Weyland, C. S., Gumbinger, C., Ringleb, P. A., Bendszus, M., Pfaff, J. A. R., Möhlenbruch, M. A. Tags: Ischemic stroke Source Type: research

In-thrombus thrombin secretion: a new diagnostic marker of atrial fibrillation in cryptogenic stroke
Conclusions An assay measuring the change in thrombin in clots retrieved during acute stroke endovascular thrombectomy procedures may serve as a diagnostic marker of the origin of the clot. The suggested mechanism for these differences may be the clot location before its retrieval, with high blood flow causing thrombin washout in atherosclerotic clots, in contrast to atrium appendage low blood flow retaining high thrombin levels.
Source: Journal of NeuroInterventional Surgery - August 13, 2021 Category: Neurosurgery Authors: Itsekson Hayosh, Z., Abu Bandora, E., Shelestovich, N., Nulman, M., Bakon, M., Yaniv, G., Khaitovitch, B., Balan, S., Gerasimova, A., Drori, T., Mausbach, S., Schwammenthal, Y., Afek, A., Chapman, J., Shavit Stein, E., Orion, D. Tags: Ischemic stroke Source Type: research

Is a picture-perfect thrombectomy necessary in acute ischemic stroke?
Conclusions Complete and near-complete reperfusion after MT appear to confer comparable outcomes in patients with acute stroke.
Source: Journal of NeuroInterventional Surgery - January 18, 2022 Category: Neurosurgery Authors: Chen, C.-J., Chalhoub, R., Ding, D., Kumar, J. S., Ironside, N., Kellogg, R. T., Worrall, B. B., Southerland, A. M., Jabbour, P., Wolfe, S. Q., Arthur, A. S., Goyal, N., Fragata, I., Maier, I., Matouk, C., Grossberg, J. A., Kan, P., Schirmer, C. M., Crowl Tags: Editor''s choice, Ischemic stroke Source Type: research

Carotid web: an under-recognized and misdiagnosed ischemic stroke etiology
Conclusion CaW was predominantly identified in patients with strokes/TIAs rather than asymptomatic patients. CaW was commonly overlooked in facilities with lower levels of cerebrovascular certification. Recognition of CaW at a CSC has significantly increased over time, independent of overall imaging and stroke patient volume.
Source: Journal of NeuroInterventional Surgery - January 18, 2022 Category: Neurosurgery Authors: Osehobo, E. M., Nogueira, R. G., Koneru, S., Al-Bayati, A. R., de Camara, C. P., Nahab, F., Liberato, B., Frankel, M. R., Allen, J. W., Park, C. C., Haussen, D. C. Tags: Ischemic stroke Source Type: research

Mapping access to endovascular stroke care in the USA and implications for transport models
Conclusion Nearly one-third of the US population lacks 60 min access to endovascular stroke care, but this is highly variable. Transport models and planning of additional centers should be tailored to each state depending on location and proximity of existing facilities.
Source: Journal of NeuroInterventional Surgery - January 18, 2022 Category: Neurosurgery Authors: Aldstadt, J., Waqas, M., Yasumiishi, M., Mokin, M., Tutino, V. M., Rai, H. H., Chin, F., Levy, B. R., Rai, A. T., Mocco, J., Snyder, K. V., Davies, J. M., Levy, E. I., Siddiqui, A. H. Tags: Ischemic stroke Source Type: research

Rates of adverse events in patients with ischemic stroke treated at thrombectomy capable hospitals
Conclusions A decrease in-hospital adverse events and improved discharge outcomes were observed among patients with ischemic stroke admitted to a TCH compared with a non-TCH.
Source: Journal of NeuroInterventional Surgery - March 18, 2022 Category: Neurosurgery Authors: Chaudhry, S. A., Sadaf, H., Laleka, I., Nasir, W., Witzel, C., Bahiru, Z., Fang, Y., Ishfaq, F., Altaweel, L. R., Qureshi, A. I. Tags: Ischemic stroke Source Type: research

Factors influencing thrombectomy decision making for primary medium vessel occlusion stroke
Conclusions Most physicians in this survey were interventionalists and would treat patients with MeVO stroke immediately with EVT. This finding supports the need for robust clinical evidence.
Source: Journal of NeuroInterventional Surgery - March 18, 2022 Category: Neurosurgery Authors: Cimflova, P., Kappelhof, M., Singh, N., Kashani, N., Ospel, J. M., McDonough, R., Demchuk, A. M., Menon, B. K., Sakai, N., Chen, M., Fiehler, J., Goyal, M. Tags: Ischemic stroke Source Type: research

Analysis of microRNA signatures in ischemic stroke thrombus
Conclusions The microRNA expression pattern can provide information regarding the mechanism of stroke by reflecting the underlying pathological status of the organ from which the thrombus was derived.
Source: Journal of NeuroInterventional Surgery - April 12, 2022 Category: Neurosurgery Authors: Kim, J.-M., Byun, J.-S., Kim, J., Park, M.-S., Hong, S. A., Nam, T.-K., Choi, H. H., Hong, S., Han, S.-H., Jeong, H.-B., Park, K.-Y., Kim, H. R. Tags: Ischemic stroke Source Type: research

Predictors of poor outcome despite successful endovascular treatment for ischemic stroke: results from the MR CLEAN Registry
Conclusion Baseline patient factors and postprocedural adverse events are important predictors of poor functional outcome in successfully reperfused patients with ischemic stroke. This implies that prevention of postprocedural adverse events has the greatest potential to further improve outcomes in these patients.
Source: Journal of NeuroInterventional Surgery - June 16, 2022 Category: Neurosurgery Authors: van de Graaf, R. A., Samuels, N., Chalos, V., Lycklama a Nijeholt, G. J., van Beusekom, H., Yoo, A. J., van Zwam, W. H., Majoie, C. B. L. M., Roos, Y. B. W. E. M., van Doormaal, P. J., Ben Hassen, W., van der Lugt, A., Dippel, D. W. J., Lingsma, H. F., va Tags: Ischemic stroke Source Type: research

Gene expression profiles of ischemic stroke clots retrieved by mechanical thrombectomy are associated with disease etiology
Conclusions Expression profiles of stroke clots were identified between stroke etiologies and reflected different biologic responses. Cryptogenic thrombi may be related to multiple etiologies.
Source: Journal of NeuroInterventional Surgery - August 29, 2023 Category: Neurosurgery Authors: Tutino, V. M., Fricano, S., Chien, A., Patel, T. R., Monteiro, A., Rai, H. H., Dmytriw, A. A., Chaves, L. D., Waqas, M., Levy, E. I., Poppenberg, K. E., Siddiqui, A. H. Tags: Ischemic stroke Source Type: research