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Specialty: Neurosurgery

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Total 6508 results found since Jan 2013.

Impact of collaterals on the efficacy and safety of endovascular treatment in acute ischaemic stroke: a systematic review and meta-analysis
Conclusions Good pretreatment collateral status is associated with higher rates of favourable functional outcome, and lower rates of symptomatic intracranial haemorrhage and mortality, in patients with acute ischaemic stroke receiving endovascular therapies.
Source: Journal of Neurology, Neurosurgery and Psychiatry - April 13, 2016 Category: Neurosurgery Authors: Leng, X., Fang, H., Leung, T. W. H., Mao, C., Miao, Z., Liu, L., Wong, K. S., Liebeskind, D. S. Tags: Stroke Cerebrovascular disease Source Type: research

Early arrival at the emergency department is associated with better collaterals, smaller established infarcts and better clinical outcomes with endovascular stroke therapy: SWIFT study
Conclusions Time was a critical factor in successful clinical outcomes for neurothrombectomy in the SWIFT trial. Shorter times to presentation were associated with better collaterals, smaller established infarcts, and better clinical outcome after revascularization.
Source: Journal of NeuroInterventional Surgery - May 12, 2016 Category: Neurosurgery Authors: Liebeskind, D. S., Jahan, R., Nogueira, R. G., Jovin, T. G., Lutsep, H. L., Saver, J. L., for the SWIFT Investigators Tags: Editor''s choice, Ischemic stroke Source Type: research

Mechanical thrombectomy for acute ischemic stroke with cerebral microbleeds
Conclusions Patients with CMBs are not at increased risk for HT and mortality following mechanical thrombectomy for acute stroke. Excluding such patients from mechanical thrombectomy is unwarranted. The risk of HT in patients with ≥5 CMBs requires further study.
Source: Journal of NeuroInterventional Surgery - May 12, 2016 Category: Neurosurgery Authors: Shi, Z.-S., Duckwiler, G. R., Jahan, R., Tateshima, S., Gonzalez, N. R., Szeder, V., Saver, J. L., Kim, D., Ali, L. K., Starkman, S., Vespa, P. M., Salamon, N., Villablanca, J. P., Vinuela, F., Feng, L., Loh, Y., Liebeskind, D. S. Tags: Ischemic stroke Source Type: research

Severe hemiparesis as a prehospital tool to triage stroke severity: a pilot study to assess diagnostic accuracy and treatment times
Conclusions We have presented a pilot study showing that severe hemiparesis or hemiplegia may be a reasonable prehospital tool in recognizing patients requiring endovascular treatment. Patients being identified earlier may be treated faster and potentially improve outcomes. Further prospective controlled studies are required to assess the impact on outcomes and cost effectiveness using this methodology.
Source: Journal of NeuroInterventional Surgery - July 13, 2016 Category: Neurosurgery Authors: Gupta, R., Manuel, M., Owada, K., Dhungana, S., Busby, L., Glenn, B. A., Brown, D., Zimmermann, S. A., Horn, C., Rochestie, D., Hormes, J. T., Johnson, A. K., Khaldi, A. Tags: Ischemic stroke Source Type: research

Unwanted detachment of the Solitaire device during mechanical thrombectomy in acute ischemic stroke
Conclusions Unwanted detachment of a Solitaire is an uncommon complication during mechanical thrombectomy in patients with acute ischemic stroke and is associated with the clot retrieval attempts, SICH, poor outcome, and higher mortality.
Source: Journal of NeuroInterventional Surgery - November 14, 2016 Category: Neurosurgery Authors: Castano, C., Dorado, L., Remollo, S., Garcia-Bermejo, P., Gomis, M., Perez de la Ossa, N., Millan, M., Garcia-Sort, M. R., Hidalgo, C., Lopez-Cancio, E., Cubells, C., Davalos, A. Tags: Ischemic stroke Source Type: research

Venous imaging-based biomarkers in acute ischaemic stroke
Vascular neuroimaging plays a decisive role in selecting the best therapy in patients with acute ischaemic stroke. However, compared with the arterial system, the role of veins has not been thoroughly studied. In this review, we present the major venous imaging-based biomarkers in ischaemic stroke. First, the presence of hypodense veins in the monophasic CT angiography ipsilateral to the arterial occlusion. Second, the asymmetry of venous drainage in the pathological cerebral hemisphere on CT and MRI dynamic angiography. Finally, the presence of hypodense veins on T2* -based MRI. From the physiological point of view, the v...
Source: Journal of Neurology, Neurosurgery and Psychiatry - December 14, 2016 Category: Neurosurgery Authors: Munuera, J., Blasco, G., Hernandez-Perez, M., Daunis-i-Estadella, P., Davalos, A., Liebeskind, D. S., Wintermark, M., Demchuk, A., Menon, B. K., Thomalla, G., Nael, K., Pedraza, S., Puig, J. Tags: Stroke, Radiology, Radiology (diagnostics) Cerebrovascular disease Source Type: research

ASPECTS discrepancies between CT and MR imaging: analysis and implications for triage protocols in acute ischemic stroke
Conclusions The study suggests that patients with NIHSS scores at admission of <16 and patients with CT ASPECTS >7 have a higher likelihood of agreement between CT and DWI based on an ASPECTS cut-off value of 6. Additional MRI for triage in patients with NIHSS at admission of >16, and ASPECTS of 6 or 7 may be more likely to change management. Unsurprisingly, patients with low CT ASPECTS had good correlation with MRI ASPECTS.
Source: Journal of NeuroInterventional Surgery - February 13, 2017 Category: Neurosurgery Authors: Hui, F. K., Obuchowski, N. A., John, S., Toth, G., Katzan, I., Wisco, D., Cheng-Ching, E., Uchino, K., Man, S.-M., Hussain, S. Tags: Ischemic stroke Source Type: research

Weekend effect in endovascular stroke treatment: do treatment decisions, procedural times, and outcome depend on time of admission?
Conclusions It is possible to produce competitive procedural times regardless of the time of admission and to prevent a treatment decision bias when standard operating procedures are applied consistently.
Source: Journal of NeuroInterventional Surgery - March 15, 2017 Category: Neurosurgery Authors: Nikoubashman, O., Probst, T., Schürmann, K., Othman, A. E., Matz, O., Brockmann, M.-A., Müller, M., Wiesmann, M., Reich, A. Tags: Ischemic stroke Source Type: research

Primary acute stroke thrombectomy within 3 h for large artery occlusion (PAST3-LAO): a pilot study
Conclusions Our study demonstrates that primary SRT in AIS from LAO is safe and feasible and is associated with complete recanalization and good outcome. Further study is required.
Source: Journal of NeuroInterventional Surgery - March 15, 2017 Category: Neurosurgery Authors: Lodi, Y., Reddy, V., Petro, G., Devasenapathy, A., Hourani, A., Chou, C.-A. Tags: Ischemic stroke Source Type: research

Distinction between contrast staining and hemorrhage after endovascular stroke treatment: one CT is not enough
Conclusions There are no density thresholds for PCHDs that allow predicting the absence or presence of hemorrhage with 100% specificity and acceptable sensitivity. A CT scan performed at least 19–24 h after endovascular therapy is the only reliable method to differentiate contrast staining from hemorrhage.
Source: Journal of NeuroInterventional Surgery - March 15, 2017 Category: Neurosurgery Authors: Dekeyzer, S., Nikoubashman, O., Lutin, B., De Groote, J., Vancaester, E., De Blauwe, S., Hemelsoet, D., Wiesmann, M., Defreyne, L. Tags: Ischemic stroke Source Type: research

Two-year single-center experience with the 'Baby Trevo stent retriever for mechanical thrombectomy in acute ischemic stroke
Conclusions Our preliminary data suggest that the ‘Baby Trevo’ achieves a high recanalization rate without any significant risk. Larger cohort studies are needed to validate the clinical benefit.
Source: Journal of NeuroInterventional Surgery - May 30, 2017 Category: Neurosurgery Authors: Kühn, A. L., Wakhloo, A. K., Lozano, J. D., Massari, F., De Macedo Rodrigues, K., Marosfoi, M. G., Perras, M., Brooks, C., Howk, M., Rex, D. E., Gounis, M. J., Puri, A. S. Tags: Ischemic stroke Source Type: research

Impact of ASPECT scores and infarct distribution on outcomes among patients undergoing thrombectomy for acute ischemic stroke with the ADAPT technique
Conclusions Patients with moderate-sized core infarcts involving various distributions in either hemisphere can potentially achieve similar good outcomes compared with those with no core infarction at presentation. A treatment algorithm for acute ischemic stroke, which employs hardline ASPECTS thresholds or excludes patients with basal ganglia infarcts, might preclude patients who would potentially benefit from mechanical thrombectomy with ADAPT.
Source: Journal of NeuroInterventional Surgery - August 17, 2017 Category: Neurosurgery Authors: Hungerford, J. P., Hyer, M., Turk, A. S., Turner, R. D., Chaudry, M. I., Fargen, K. M., Spiotta, A. M. Tags: Ischemic stroke Source Type: research

Factors associated with successful revascularization using the aspiration component of ADAPT in the treatment of acute ischemic stroke
Conclusions Aspiration success was associated with younger age. Our findings suggest that ADAPT can be used for the vast majority of patients but it may be beneficial to use a different method first in the elderly.
Source: Journal of NeuroInterventional Surgery - June 16, 2017 Category: Neurosurgery Authors: Mascitelli, J. R., Kellner, C. P., Oravec, C. S., De Leacy, R. A., Oermann, E. K., Yaeger, K., Paramasivam, S., Fifi, J. T., Mocco, J. Tags: Ischemic stroke Source Type: research

Quantified health and cost effects of faster endovascular treatment for large vessel ischemic stroke patients in the Netherlands
Conclusion One-minute faster EVT increases QALYs while cumulative costs remain largely unaffected. Therefore, faster EVT provides better value of care at no extra healthcare costs.
Source: Journal of NeuroInterventional Surgery - November 18, 2021 Category: Neurosurgery Authors: van Voorst, H., Kunz, W. G., van den Berg, L. A., Kappelhof, M., Pinckaers, F. M. E., Goyal, M., Hunink, M. G. M., Emmer, B. J., Mulder, M. J. H. L., Dippel, D. W. J., Coutinho, J. M., Marquering, H. A., Boogaarts, H. D., van der Lugt, A., van Zwam, W. H. Tags: Open access, Ischemic stroke Source Type: research

Per-pass analysis of acute ischemic stroke clots: impact of stroke etiology on extracted clot area and histological composition
Conclusion LAA clots are larger and associated with a large red blood cell-rich extracted clot area, suggesting soft thrombus material. Cardioembolic clots are smaller in the extracted clot area, consistent in composition and area across passes, and have higher fibrin and platelets/other content than LAA clots, making them stiffer clots. The per-pass histological composition and extracted clot area of cryptogenic clots are similar to those of cardioembolic clots, suggesting similar formation mechanisms.
Source: Journal of NeuroInterventional Surgery - November 18, 2021 Category: Neurosurgery Authors: Fitzgerald, S., Rossi, R., Mereuta, O. M., Jabrah, D., Okolo, A., Douglas, A., Molina Gil, S., Pandit, A., McCarthy, R., Gilvarry, M., Dunker, D., Nordanstig, A., Ceder, E., Redfors, P., Jood, K., Dehlfors, N., Magoufis, G., Tsivgoulis, G., Brinjikji, W., Tags: Open access, Ischemic stroke Source Type: research