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Specialty: Neurosurgery

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Total 6508 results found since Jan 2013.

Endovascular treatment of acute ischemic stroke in nonagenarians compared with younger patients in a multicenter cohort
Conclusions Nonagenarians are at a substantially higher risk of a poor 90-day outcome after EVT than younger patients. However, a small subset of nonagenarians may benefit from EVT, particularly if they have a good pre-stroke functional status. Further research is needed to identify factors associated with favorable outcome in this age cohort.
Source: Journal of NeuroInterventional Surgery - July 12, 2017 Category: Neurosurgery Authors: Khan, M. A., Baird, G. L., Miller, D., Patel, A., Tsekhan, S., Yaghi, S., Puri, A., Jayaraman, M., Henninger, N., Silver, B. Tags: Ischemic stroke Source Type: research

Endovascular treatment beyond 24 hours from the onset of acute ischemic stroke: the Italian Registry of Endovascular Thrombectomy in Acute Stroke (IRETAS)
Conclusions These findings suggest that, in a real world setting, very late endovascular therapy is feasible in appropriately selected patients.
Source: Journal of NeuroInterventional Surgery - November 14, 2022 Category: Neurosurgery Authors: Casetta, I., Fainardi, E., Pracucci, G., Saia, V., Vallone, S., Zini, A., Bergui, M., Cerrato, P., Nappini, S., Nencini, P., Gasparotti, R., Saletti, A., Causin, F., Romano, D., Burdi, N., Giorgianni, A., Mangiafico, S., Toni, D., The Italian Registry of Tags: Ischemic stroke Source Type: research

Evaluation of direct-to-angiography suite (DTAS) and conventional clinical pathways in stroke care: a simulation study
Conclusions The results of the SimStroke model showed comparable time intervals for door-to-reperfusion for DTAS compared with a conventional stroke care pathway. However, the DTAS pathway was very sensitive to baseline angiography suite utilization, with even a 10% increase eliminating the advantages of DTAS compared with the conventional pathway. Given the minimal time savings modeled here, further investigation of implementing the DTAS pathway in clinical care is warranted.
Source: Journal of NeuroInterventional Surgery - November 14, 2022 Category: Neurosurgery Authors: Bastani, M., White, T. G., Martinez, G., Ohara, J., Sangha, K., Gribko, M., Katz, J. M., Woo, H. H., Boltyenkov, A. T., Wang, J., Rula, E., Naidich, J. J., Sanelli, P. C. Tags: Ischemic stroke Source Type: research

Clinical relevance and practical implications of trials of perfusion and angiographic imaging in patients with acute ischaemic stroke: a multicentre cohort imaging study
Conclusion Early recanalisation on angiography appeared to predict clinical outcome more directly than did tissue reperfusion. Acute assessment with CT and follow-up with MR was practical and feasible, did not preclude image analysis, and would enhance trial recruitment and generalisability of results.
Source: Journal of Neurology, Neurosurgery and Psychiatry - August 6, 2013 Category: Neurosurgery Authors: Wardlaw, J. M., Muir, K. W., Macleod, M.-J., Weir, C., McVerry, F., Carpenter, T., Shuler, K., Thomas, R., Acheampong, P., Dani, K., Murray, A. Tags: Open access, Stroke, Radiology, Radiology (diagnostics) Cerebrovascular disease Source Type: research

Identification of missed hypertension and hypertensive arteriopathy with home versus ambulatory blood pressure measurement in patients with tia or minor stroke
Conclusions In patients with TIA or minor stroke, HBPM was more reliable than ABPM at identifying missed hypertension and hypertensive arteriopathy. Its use could significantly reduce the risk of recurrent stroke.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Webb, A., Li, L., Simoni, M., Wilson, M., Paul, N., Tarassenko, L., Rothwell, P. Tags: Neuroimaging, Stroke, Hypertension Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

Sensitivity of transcranial doppler and transoesophageal echocardiography for the detection of patent foramen ovale in cryptogenic stroke
Conclusions TCD with bubble test is sensitive and specific for the detection of right–to–left shunts due to PFO confirmed at right heart catheterisation. In this population, TOE had low sensitivity for RLS. There was no difference in physical PFO size between TOE positive and negative patients.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Morhij, D., Dani, K., Stewart Hillis, W., Muir, K. Tags: Headache (including migraine), Neuroimaging, Stroke, Hypertension, Ischaemic heart disease, Radiology, Radiology (diagnostics) Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

Outcomes in patients with acute ischemic stroke from proximal intracranial vessel occlusion and NIHSS score below 8
Conclusions Patients with acute stroke due to large vessel occlusion and low admission NIHSS scores (0–7 range) may have poor functional outcomes at discharge. These patients, if not eligible for IV thrombolysis, might benefit from IA revascularization therapies.
Source: Journal of NeuroInterventional Surgery - June 28, 2014 Category: Neurosurgery Authors: Mokin, M., Masud, M. W., Dumont, T. M., Ahmad, G., Kass-Hout, T., Snyder, K. V., Hopkins, L. N., Siddiqui, A. H., Levy, E. I. Tags: Ischemic stroke Source Type: research

Severity of leukoaraiosis, leptomeningeal collaterals, and clinical outcomes after intra-arterial therapy in patients with acute ischemic stroke
Conclusions Severity of LA is linked to poor collateral grade in AIS patients undergoing IAT for PAO; however, greater LAv appears not to be a contraindication for acute intervention.
Source: Journal of NeuroInterventional Surgery - April 13, 2015 Category: Neurosurgery Authors: Giurgiutiu, D.-V., Yoo, A. J., Fitzpatrick, K., Chaudhry, Z., Leslie-Mazwi, T., Schwamm, L. H., Rost, N. S. Tags: Ischemic stroke Source Type: research

Incidence and mechanisms of stroke after permanent carotid artery occlusion following temporary occlusion testing
Conclusions The rate of ischemic stroke following carotid sacrifice remains high and most strokes are thromboembolic in nature. Our testing protocol did not eliminate the risk of hypoperfusion-related stroke. Delayed venous phase by angiography may be a better indicator of hemodynamic tolerance than perfusion imaging.
Source: Journal of NeuroInterventional Surgery - May 14, 2015 Category: Neurosurgery Authors: Whisenant, J. T., Kadkhodayan, Y., Cross, D. T., Moran, C. J., Derdeyn, C. P. Tags: Ischemic stroke Source Type: research

Post-stroke fatigue: a problem of altered corticomotor control?
Conclusions Previously, we showed that motor cortex excitability is lower in patients with high post-stroke fatigue. Our current findings suggest that post-stroke fatigue (1) is a problem of movement speed (possibly a consequence of diminished motor cortex excitability) and not movement preparation, and (2) may have a focal origin confined to the lesioned hemisphere. We suggest that low motor cortex excitability in the lesioned hemisphere is a viable therapeutic target in post-stroke fatigue.
Source: Journal of Neurology, Neurosurgery and Psychiatry - July 14, 2015 Category: Neurosurgery Authors: Kuppuswamy, A., Clark, E. V., Sandhu, K. S., Rothwell, J. C., Ward, N. S. Tags: JNNP Patients' choice, Stroke Cerebrovascular disease Source Type: research

Diagnostic delays in paediatric stroke
Conclusions The diagnosis of AIS in children is delayed at every stage of the pathway but most profoundly when the first neuroimaging is CT scanning, which is non-diagnostic. MRI should be the initial imaging modality of choice in any suspected case of childhood AIS.
Source: Journal of Neurology, Neurosurgery and Psychiatry - July 14, 2015 Category: Neurosurgery Authors: Mallick, A. A., Ganesan, V., Kirkham, F. J., Fallon, P., Hedderly, T., McShane, T., Parker, A. P., Wassmer, E., Wraige, E., Amin, S., Edwards, H. B., O'Callaghan, F. J. Tags: Coma and raised intracranial pressure, Stroke, Radiology, Radiology (diagnostics) Cerebrovascular disease Source Type: research

Picture-to-puncture time in acute stroke endovascular intervention: are we getting faster?
Conclusions As a consequence of systems improvement at our institution, we were able to demonstrate improved annual median P2P times from 2007 to 2013.
Source: Journal of NeuroInterventional Surgery - July 14, 2015 Category: Neurosurgery Authors: van Heerden, J., Yan, B., Churilov, L., Dowling, R. J., Mitchell, P. J. Tags: Ischemic stroke Source Type: research

Clinical outcomes of patients with acute minor stroke receiving rescue IA therapy following early neurological deterioration
Conclusions The results suggest that rescue IAT may be safe and effective when END occurs in selected patients with acute minor ischemic stroke. Further prospective and randomized studies are needed to confirm our results.
Source: Journal of NeuroInterventional Surgery - April 13, 2016 Category: Neurosurgery Authors: Kim, J.-T., Heo, S.-H., Yoon, W., Choi, K.-H., Park, M.-S., Saver, J. L., Cho, K.-H. Tags: Ischemic stroke Source Type: research

Groin complications in endovascular mechanical thrombectomy for acute ischemic stroke: a 10-year single center experience
Conclusions These findings suggest that concerns for groin complications should not preclude the use of BGCs and large-bore sheaths in mechanical thrombectomy for acute ischemic stroke.
Source: Journal of NeuroInterventional Surgery - May 12, 2016 Category: Neurosurgery Authors: Shah, V. A., Martin, C. O., Hawkins, A. M., Holloway, W. E., Junna, S., Akhtar, N. Tags: Open access, Ischemic stroke Source Type: research

Aneurysms in the target vessels of stroke patients subjected to mechanical thrombectomy: prevalence and impact on treatment
Conclusions The prevalence of aneurysms is relatively high in patients with LVO stroke, particularly in older, female, hypertensive patients, presumably reflecting overlapping risk factors. MTE should not be withheld from patients with LVO stroke with aneurysms, but particularly cautious approaches may be warranted. Further research in larger samples is required to obtain precise data on the prevalence and associated complication rates in MTE procedures. This is necessary to estimate the true risk and to tailor endovascular strategies in these patients.
Source: Journal of NeuroInterventional Surgery - September 12, 2016 Category: Neurosurgery Authors: Zibold, F., Kleine, J. F., Zimmer, C., Poppert, H., Boeckh-Behrens, T. Tags: Ischemic stroke Source Type: research