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International study: Global impact of COVID-19 on stroke care - the Polish contribution
Neurol Neurochir Pol. 2023 Feb 2. doi: 10.5603/PJNNS.a2023.0006. Online ahead of print.NO ABSTRACTPMID:36727547 | DOI:10.5603/PJNNS.a2023.0006
Source: Neurologia i Neurochirurgia Polska - February 2, 2023 Category: Neurology Authors: Anetta Lasek-Bal Anna Cz łonkowska Muhammad M Qureshi Mohamad Abdalkader Joao Pedro Marto Patrik Michel Hiroshi Yamagami Robert Mikulik Jelle Demeestere Zhongming Qiu Thanh N Nguyen Raul G Nogueira Source Type: research

Relevance of admission hyperglycaemia and diabetes mellitus to efficacy and safety of mechanical thrombectomy in stroke patients
CONCLUSIONS: Diabetes mellitus has a neutral effect on the angiographic and clinical outcomes of mechanical thrombectomy in stroke patients. It does not increase the risk of intracranial haemorrhage after instrumental therapy. It is admission hyperglycaemia, rather than diabetes mellitus, that is a predictor of poor functional status in patients treated with thrombectomy. According to our results, the patient's neurological status, age, and the outcome of thrombectomy are relevant to the functional status in the acute ischaemic stroke period.PMID:36394219 | DOI:10.5603/PJNNS.a2022.0063
Source: Neurologia i Neurochirurgia Polska - November 17, 2022 Category: Neurology Authors: Anetta Lasek-Bal Amadeusz Żak Łukasz Binek Sebastian Student Aleksandra Cie ślik Wies ław Bal Wiktor Rybicki Jolanta Kulawik-Szwajca Source Type: research

Epidemiological analysis of hospitalisations due to recurrent stroke in the Silesian Province, Poland, between 2009 and 2015.
CONCLUSIONS: This is the first such comprehensive and long-term analysis of recurrent stroke in Silesia, Poland. It could help in the implementation of appropriate educational programmes, and thus help to improve the health status of society. PMID: 31441494 [PubMed - as supplied by publisher]
Source: Neurologia i Neurochirurgia Polska - August 22, 2019 Category: Neurology Authors: Łabuz-Roszak B, Skrzypek M, Starostka-Tatar A, Lasek-Bal A, Gąsior M, Gierlotka M Tags: Neurol Neurochir Pol Source Type: research

The importance of selected markers of inflammation and blood-brain barrier damage for short-term ischemic stroke prognosis.
Authors: Lasek-Bal A, Jedrzejowska-Szypulka H, Student S, Warsz-Wianecka A, Zareba K, Puz P, Bal W, Pawletko K, Lewin-Kowalik J Abstract Acute cerebral ischemia triggers local and systemic immune response. The aims of this project was to assess the blood serum concentration of the markers of inflammation and markers of the blood brain barrier damage on the first day of ischemic stroke, and the mutual correlations between these marker levels. Patients with first-in-life stroke were analysed according to: plasma concentration of the following markers on the first day of stroke: interleukin 2 (IL-2) and interleuki 6 (...
Source: Journal of Physiology and Pharmacology - July 31, 2019 Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research

Connecting Metainflammation and Neuroinflammation Through the PTN-MK-RPTP β/ζ Axis: Relevance in Therapeutic Development
Conclusion The expression of the components of the PTN-MK-RPTPβ/ζ axis in immune cells and in inflammatory diseases suggests important roles for this axis in inflammation. Pleiotrophin has been recently identified as a limiting factor of metainflammation, a chronic pathological state that contributes to neuroinflammation and neurodegeneration. Pleiotrophin also seems to potentiate acute neuroinflammation independently of the inflammatory stimulus while MK seems to play different -even opposite- roles in acute neuroinflammation depending on the stimulus. Which are the functions of MK and PTN in chronic neuroi...
Source: Frontiers in Pharmacology - April 11, 2019 Category: Drugs & Pharmacology Source Type: research

Analysis of echocardiographic parameters of cardiac function in patients with acute stroke.
CONCLUSIONS: One quarter of patients in the acute phase of stroke have LVSD and/or LVDD. LVSD adversely affects both neurological status in acute stroke as well as functional status in the short-term follow-up. Age at first-in-life stroke incidence and lower EF are predictors of poor functional status one month after a stroke. PMID: 30855702 [PubMed - as supplied by publisher]
Source: Neurologia i Neurochirurgia Polska - March 10, 2019 Category: Neurology Authors: Lasek-Bal A, Żak A, Pysz P, Puz P, Gąsior Z Tags: Neurol Neurochir Pol Source Type: research

BOLD fMRI signal in stroke patients and its importance for prognosis in the subacute disease period – Preliminary report
ConclusionThere are differences observed in the activation areas of the cerebral cortex both in the stroke and non-stroke hemispheres. More than half of the patients with hemispheric stroke but all with good outcome showed cerebellar activation. There is probable positive correlation between the BOLD-signal size, young age, activation of supplementary motor area in stroke hemisphere and good functional status of patients in the subacute period of stroke.
Source: Polish Journal of Neurology and Neurosurgery - July 10, 2018 Category: Neurosurgery Source Type: research

The importance of atrial fibrillation and selected echocardiographic parameters for the effectiveness and safety of thrombolytic therapy in patients with stroke
ConclusionsThe presence of atrial fibrillation worsens the patient's prognosis in terms of the functional status and survival during the acute period of stroke in patients treated with intravenous thrombolysis.Higher NIHSS and CHA2DS2VASc scores and reduced EF in patients with stroke treated with thrombolysis are the predictors of unfavorable short-term prognosis.
Source: Polish Journal of Neurology and Neurosurgery - July 10, 2018 Category: Neurosurgery Source Type: research

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