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The association between intraoperative fluid management and perioperative allogenic blood transfusion during adolescent idiopathic scoliosis surgery
CONCLUSION: These results indicate a statistical association between the increase in crystalloid intake and the risk of allogenic blood transfusion during surgical correction of adolescent idiopathic scoliosis. Controlled studies are needed to address the causative relation between intraoperative fluid intake and the risk of allogenic transfusion.PMID:37386846 | DOI:10.1111/pan.14722
Source: Paediatric Anaesthesia - June 30, 2023 Category: Anesthesiology Authors: Pierre Pardessus Maud Loiselle Vilnis Silins Anne-Laure Horlin Kelly Brouns Lucile Marsac Charlotte Fait Brice Ilharreborde Florence Julien-Marsollier Souhayl Dahmani Source Type: research

Blood Transfusions In Elective Cardiac Surgery- The debate continues
In this issue of the Journal of Cardiothoracic and Vascular Anesthesia, Sanaiha et al presented a manuscript entitled “Morbidity and Mortality Associated with Blood Transfusions in Elective Adult Cardiac Surgery.” The authors looked at the association between transfusions of stored packed red blood cells (pRBC) or coagulation products (CP), and the increased risk of 30 day mortality, prolonged mechanical ventil ation, acute kidney injury and stroke in patients undergoing elective cardiac surgery.
Source: Journal of Cardiothoracic and Vascular Anesthesia - May 26, 2023 Category: Anesthesiology Authors: Sofia A Lifgren, Robert Scott Fiala, Michael Fabbro Tags: Editorial Source Type: research

Blood Transfusions in Elective Cardiac Surgery: The Debate Continues
In this issue of the Journal of Cardiothoracic and Vascular Anesthesia, Sanaiha et al. presented a manuscript entitled “Morbidity and Mortality Associated With Blood Transfusions in Elective Adult Cardiac Surgery.” The authors examined the association between transfusions of stored packed red blood cells (pRBC) or coagulation products (CP) and the increased risk of 30-day mortality, prolonged mechanical ventilat ion, acute kidney injury, and stroke in patients undergoing elective cardiac surgery.
Source: Journal of Cardiothoracic and Vascular Anesthesia - May 26, 2023 Category: Anesthesiology Authors: Sofia A. Lifgren, Robert Scott Fiala, Michael Fabbro Tags: Editorial Source Type: research

Perioperative Red Blood Cell Transfusion Is Associated With Adverse Cardiovascular Outcomes in Heart Valve Surgery
CONCLUSIONS: In the analysis of the national cohort, perioperative RBC transfusion during heart valve surgery was associated with adverse cardiovascular outcomes correlated with the volume of RBC transfusion.PMID:36730895 | DOI:10.1213/ANE.0000000000006245
Source: Anesthesia and Analgesia - February 2, 2023 Category: Anesthesiology Authors: Hee Jung Kim Ji Eon Kim Ji Yoon Lee Seung Hyung Lee Jae Seung Jung Ho Sung Son Source Type: research

Perioperative Quality Initiative and Enhanced Recovery After Surgery-Cardiac Society Consensus Statement on the Management of Preoperative Anemia and Iron Deficiency in Adult Cardiac Surgery Patients
Anesth Analg. 2022 Sep 1;135(3):532-544. doi: 10.1213/ANE.0000000000006148. Epub 2022 Aug 17.ABSTRACTPreoperative anemia is common in patients presenting for cardiac surgery, with a prevalence of approximately 1 in 4, and has been associated with worse outcomes including increased risk of blood transfusion, kidney injury, stroke, infection, and death. Iron deficiency, a major cause of anemia, has also been shown to have an association with worse outcomes in patients undergoing cardiac surgery, even in the absence of anemia. Although recent guidelines have supported diagnosing and treating anemia and iron deficiency before ...
Source: Anesthesia and Analgesia - August 17, 2022 Category: Anesthesiology Authors: Nicole R Guinn Jonathon Schwartz Rakesh C Arora Vicki Morton-Bailey Solomon Aronson Charles Scott Brudney Elliott Bennett-Guerrero Perioperative Quality Initiative (POQI-8) and the Enhanced Recovery After Surgery-Cardiac Society (ERAS-C) Investigators Source Type: research

Perioperative Bleeding Requiring Blood Transfusions Is Associated with Increased Risk of Stroke after Transcatheter and Surgical Aortic Valve Replacement
We aimed to investigate the impact of severe bleeding and use of red blood cell (RBC) transfusion on the development of postoperative stroke after surgical (SAVR) and transcatheter aortic valve replacement (TAVR) from the FinnValve registry.
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 26, 2022 Category: Anesthesiology Authors: Tuomas Tauriainen, Tatu Juvonen, Vesa Anttila, Pasi Maaranen, Matti Niemel ä, Markku Eskola, Tuomas Ahvenvaara, Annastiina Husso, Marko P.O. Virtanen, Eeva-Maija Kinnunen, Sebastian Dahlbacka, Maina Jalava, Mika Laine, Antti Valtola, Peter Raivio, Antti Tags: Original Article Source Type: research

Morbidity and mortality in patients managed with high compared with low blood pressure targets during on-pump cardiac surgery: a systematic review and meta-analysis of randomized controlled trials
ConclusionIndividual trial definitions of high and low blood pressure targets varied, limiting inferences. The effect of high (compared with low) blood pressure targets on other morbidity and mortality after cardiac surgery remains unclear because of limitations with the body of existing evidence. Research to determine the optimal management of blood pressure during cardiac surgery is required.Study registrationPROSPERO (CRD42020177376); registered: 5 July 2020.
Source: Canadian Journal of Anesthesia - February 17, 2022 Category: Anesthesiology Source Type: research

Safety of Tranexamic Acid in Hip and Knee Arthroplasty in High-risk Patients
ConclusionsAlthough effective in reducing blood transfusions, tranexamic acid is not associated with increased complications, irrespective of patient high-risk status at baseline.Editor ’s PerspectiveWhat We Already Know about This TopicThe use of tranexamic acid to decrease blood loss during lower-extremity arthroplasty is commonplaceSafety concerns remain for patients with a history of thromboembolic, cardiovascular, renal, or neurologic comorbiditiesWhat This Article Tells Us That Is NewNational administrative data from more than 500 hospitals and 40,000 patients demonstrate that approximately half of high-risk patien...
Source: Anesthesiology - June 9, 2021 Category: Anesthesiology Source Type: research

Viable Hemostasis Obtained With Prothrombin Complex Concentrate in Patients Who Refuse Standard Allogeneic Blood Transfusion and Undergo Complex Cardiac Surgery: A Case Series
Human 4-factor prothrombin complex concentrate (4F-PCC) may reduce blood loss during surgery. This case series described perioperative outcomes among 9 patients who refused standard allogeneic blood transfusion, underwent complex cardiac surgery with aortic involvement, and received intraoperative 4F-PCC. Additional intraoperative cointerventions included protamine (n = 9), aminocaproic acid (n = 8), fibrinogen concentrate (n = 6), desmopressin (n = 6), factor VIIa (n = 2), and tranexamic acid (n = 1). Outcomes included postoperative death (n = 1), major postoperative bleeding (n = 1), deep vein thrombosis (n = 2), and isc...
Source: A&A Case Reports - July 1, 2020 Category: Anesthesiology Tags: Case Series Source Type: research

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