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Outcomes after aortic valve replacement for aortic valve stenosis, with or without concomitant coronary artery bypass grafting
ConclusionsConcomitant CABG at the time of AVR was performed without increasing early- or mid-term mortality. This absence of increased risk deserves consideration when choosing between different treatment strategies.
Source: General Thoracic and Cardiovascular Surgery - December 17, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research

In ‐hospital outcomes of transcatheter versus surgical aortic valve replacement in non‐teaching hospitals
ConclusionsTAVR conferred similar in ‐hospital mortality and major peri‐procedural complications compared with SAVR in non‐teaching hospitals. For those with limited access to teaching hospitals, non‐teaching hospitals appear to be a reasonable option for candidates of aortic valve replacement for severe aortic stenosis.
Source: Catheterization and Cardiovascular Interventions - November 8, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Tomo Ando, Oluwole Adegbala, Pedro A. Villablanca, Alexandros Briasoulis, Hisato Takagi, Cindy L. Grines, Theodore Schreiber, Tamim Nazif, Susheel Kodali, Luis Afonso Tags: VALVULAR AND STRUCTURAL HEART DISEASES Source Type: research

Hemiarch Reconstruction Versus Clamped Aortic Anastomosis for Concomitant Ascending Aortic Aneurysm
ConclusionsHemiarch replacement using DHCA with RCP does not increase the risk of operative complications compared with a normothermic, clamped-distal aortic anastomosis, and therefore its use should not be limited when planning complex multiprocedural reconstructions during elective ascending thoracic aortic replacement with concomitant cardiac surgery.
Source: The Annals of Thoracic Surgery - August 21, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research

Hemiarch Reconstruction Vs Clamped Aortic Anastomosis for Concomitant Ascending Aortic Aneurysm
Conclusions Hemiarch replacement using DHCA with RCP does not increase the risk of operative complications compared to a normothermic, clamped-distal aortic anastomosis, and therefore its use should not be limited when planning complex multi-procedural reconstructions during elective ascending thoracic aortic replacement with concomitant cardiac surgery.
Source: The Annals of Thoracic Surgery - May 4, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research

Hemiarch Reconstruction Vs Clamped Aortic Anastomosis for Concomitant Ascending Aortic Aneurysm.
CONCLUSIONS: Hemiarch replacement using DHCA with RCP does not increase the risk of operative complications compared to a normothermic, clamped-distal aortic anastomosis, and therefore its use should not be limited when planning complex multi-procedural reconstructions during elective ascending thoracic aortic replacement with concomitant cardiac surgery. PMID: 29730345 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - May 3, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Sultan I, Bianco V, Yajzi I, Kilic A, Dufendach K, Cardounel A, Althouse AD, Masri A, Navid F, Gleason TG Tags: Ann Thorac Surg Source Type: research

Long-Term Outcomes of Patients With Mediastinal Radiation-Associated Severe Aortic Stenosis and Subsequent Surgical Aortic Valve Replacement: A Matched Cohort Study Valvular Heart Disease
BackgroundCardiac disease after mediastinal radiotherapy for thoracic malignancy (chest radiotherapy [XRT]) often manifests as progressive aortic stenosis. In patients with XRT‐induced severe aortic stenosis undergoing surgical aortic valve replacement (SAVR), we sought to: (1) study long‐term survival and compare these patients with a matched cohort undergoing SAVR during the same time frame; and (2) identify potential predictors of long‐term mortality.Methods and ResultsWe studied patients with symptomatic severe aortic stenosis undergoing SAVR at our institution, of which there were 172 mediastinal XRT patients (6...
Source: JAHA:Journal of the American Heart Association - May 5, 2017 Category: Cardiology Authors: Donnellan, E., Masri, A., Johnston, D. R., Pettersson, G. B., Rodriguez, L. L., Popovic, Z. B., Roselli, E. E., Smedira, N. G., Svensson, L. G., Griffin, B. P., Desai, M. Y. Tags: Valvular Heart Disease Original Research Source Type: research

Transaortic Transcatheter Aortic Valve Implantation and Concomitant Off Pump Revascularization
We present 4 successfully combined off-pump procedures consisting of a transcatheter aortic valve implantation (Edwards SAPIEN XT) via the transaortic approach and an off-pump coronary artery bypass grafting. All patients were discharged free from stroke, myocardial infarction, or access site complications either to rehabilitation facility or to the referring hospital with none or trace aortic regurgitation and patent grafts. These cases confirm the feasibility of those combined operations and should be considered as realistic alternative for surgical treatment in high-risk patients who are clearly identified to benefit fr...
Source: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery - September 1, 2016 Category: Cardiovascular & Thoracic Surgery Tags: Case Reports Source Type: research

Aortic Valve Replacement in the Moderately Elevated Risk Patient: A Population-Based Analysis of Outcomes.
CONCLUSIONS: This population-based contemporary assessment suggests moderate-risk patients undergoing AVR experience favorable outcomes. Although increasing PROM is important in preoperative evaluation of risk, preexisting pulmonary hypertension and indication for operation are among other factors that should be considered as TAVR expands into this group of patients. PMID: 27324524 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - June 17, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Patel HJ, Likosky DS, Pruitt AL, Murphy ET, Theurer PF, Prager RL Tags: Ann Thorac Surg Source Type: research

Aortic Valve Replacement in the Moderately Elevated Risk Patient: A Population-Based Analysis of Outcomes
Conclusions This population-based contemporary assessment suggests moderate-risk patients undergoing AVR experience favorable outcomes. Although increasing PROM is important in preoperative evaluation of risk, preexisting pulmonary hypertension and indication for operation are among other factors that should be considered as TAVR expands into this group of patients.
Source: The Annals of Thoracic Surgery - June 17, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research

Valve Replacement for Moderate Aortic Stenosis in Octogenarians Undergoing Revascularization.
CONCLUSION: In-hospital mortality is higher for octogenarians undergoing CABG+AVR compared to those undergoing isolated CABG. In the present study, a 'prophylactic' AVR was justified in patients with moderate AS, and their increased mortality (versus isolated CABG) was congruent with a higher preoperative co-morbid risk profile. Excellent long- term symptom-free survival further justifies 'prophylactic' AVR in octogenarians undergoing CABG with coexistent moderate AS. PMID: 26897807 [PubMed - in process]
Source: Journal of Heart Valve Disease - February 25, 2016 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Transcatheter or Surgical Aortic Valve Replacement in Patients With Prior Coronary Artery Bypass Grafting
Conclusions For patients with prior coronary artery bypass graft surgery and aortic stenosis, TAVR offers a significant morbidity advantage and a strong trend toward improved survival over SAVR at 1 year.
Source: The Annals of Thoracic Surgery - December 15, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Transcatheter or Surgical Aortic Valve Replacement in Patients With Prior Coronary Artery Bypass Grafting.
CONCLUSIONS: For patients with prior coronary artery bypass graft surgery and aortic stenosis, TAVR offers a significant morbidity advantage and a strong trend toward improved survival over SAVR at 1 year. PMID: 26433523 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - September 30, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Conte JV, Gleason TG, Resar JR, Adams DH, Deeb GM, Popma JJ, Hughes GC, Zorn GL, Reardon MJ Tags: Ann Thorac Surg Source Type: research

Trans-aortic, Video-Assisted Removal of a Mobile Left Ventricular Apical Thrombus in a Patient with Aortic Stenosis and Severe Left Ventricular Dysfunction
We describe the removal of a mobile and protruding left ventricular thrombus using a video-assisted technique during an aortic valve replacement and coronary artery bypass procedure.
Source: The Journal of Thoracic and Cardiovascular Surgery - September 27, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Christina Williamson, Lori B. Sheehan, David M. Venesy, Richard S. D’Agostino Source Type: research

Aortic Stenosis Valve Replacement or Valve Implantation? ∗
In this issue of the Journal, Tamburino et al. (1) have published a study that compares the clinical outcomes of aortic valve replacement (AVR) with transcatheter aortic valve replacement (TAVR) at 1 year from the OBSERVANT (Observational Study of Effectiveness of SAVR–TAVR Procedures for Severe Aortic Stenosis Treatment) registry, which investigates the management of aortic stenosis (AS) in 93 institutions in Italy. The registry had 7,618 patients with AS (5,707 treated with AVR and 1,991 with TAVR). The investigators excluded 2,150 patients because of combined procedures, porcelain aortas, “hostile thorax,” nonfem...
Source: Journal of the American College of Cardiology - August 10, 2015 Category: Cardiology Source Type: research

TAVI: Study finds low stroke rates with Medtronic’s CoreValve
A clinical study of nearly 1,000 patients implanted with Medtronic‘s (NYSE:MDT) CoreValve replacement heart valve found a low rate of stroke out to 2 years. The study, published last month in the Journal of the American College of Cardiology, evaluated patients for neurological events over 3 periods after the procedure to implant the CoreValve transcatheter aortic valve implant: Periprocedural (0 to 1 days); early (2 to 30 days); and late (31 to 730 days). Results from the 996-patient trial, “The Incidence and Predictors of Early- and Mid-Term Clinically Relevant Neurological Events After Transcatheter Aortic ...
Source: Mass Device - August 3, 2015 Category: Medical Equipment Authors: Brad Perriello Tags: Clinical Trials Regulatory/Compliance CoreValve Inc. medtronic Source Type: news

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