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Procedure: Carotid Endarterectomy

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Total 2934 results found since Jan 2013.

Early postoperative outcome after carotid artery endarterectomy with bifurcation advancement
Conclusions: CEA with bifurcation advancement provides comparable perioperative results, focusing on combined stroke and mortality, but seems to have some technical drawbacks, which may lead to more frequent local neurological complications.PMID:37170543 | DOI:10.1024/0301-1526/a001074
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - May 12, 2023 Category: Surgery Authors: Felix L Moehle Bernard Krueger Anna-Leonie Menges Zoran Rancic Alexander Zimmermann Source Type: research

Influences of age and gender on operative risks following carotid endarterectomy: A systematic review and meta-analysis
by Sothida Nantakool, Busaba Chuatrakoon, Saritphat Orrapin, Rachel Leung, Dominic P. J. Howard, Amaraporn Rerkasem, Jos é G. B. Derraik, Kittipan Rerkasem ObjectivesThis review aims to undertake a comprehensive review of the literature and investigate associations of age and gender on 30 days post carotid endarterectomy (CEA) and up to 5 years post CEA stroke, death, and combined stroke and death. DesignA systematic review and meta-analysis. MethodsThree main electronic databases including the Cochrane Library, MEDLINE, and Embase were searched from their inception to July 2022. Studies examining operative risks (i.e., s...
Source: PLoS One - May 10, 2023 Category: Biomedical Science Authors: Sothida Nantakool Source Type: research

Optimising Secondary Prevention: a One Year Review of Lipid Lowering Therapy (LLT) and Cholesterol Monitoring in Patients Undergoing Carotid Surgery
Objective: Stroke is common (100 000 new cases annually in the UK), with carotid atherosclerotic disease a recognised cause.1 In such cases patients may require either surgical or endovascular carotid intervention but they should also receive optimal medical therapy including lipid lowering therapy (LLT).2 Statins have been shown to reduce the 10 year risk of stroke/death (17.9% vs. 7.6%) after carotid endarterectomy.3 Current European Society for Vascular Surgery (ESVS) Guidelines advise high intensity statin (HIS) treatment with a target LDL C level of
Source: European Journal of Vascular and Endovascular Surgery - May 1, 2023 Category: Surgery Authors: J.Y. Kwan, M. Sood, F. Stocco, N. Orozov, K. Spencer-jones, M. Bailey, P. Coughlin, J. Scott Source Type: research

Effect of the Pre-Operative Systemic Inflammatory Response on Outcomes Following Carotid Endarterectomy for Symptomatic Carotid Stenosis
Objective: Stroke accounts for over 100 000 acute hospital presentations per year in the UK, and approximately 4 500 carotid endarterectomies are performed annually in the UK.1 This is despite a relative paucity of cases performed for asymptomatic carotid stenosis, in comparison with other countries.1 Periprocedural stroke and death rates have fallen in recent years,2 although these remain notable risks necessitating careful patient selection and counselling. Chronic activation of the systemic inflammatory response (SIR) is prevalent in patients with atherosclerotic disease and influences both the pathogenesis and prognosis.
Source: European Journal of Vascular and Endovascular Surgery - May 1, 2023 Category: Surgery Authors: K. Dosanj, N. Bradley, C. Roxburgh, D. Mcmillan, G. Guthrie Source Type: research

Endarterectomy Achieves Lower Stroke and Death Rates Compared With Stenting in Patients With Asymptomatic Carotid Stenosis: a Systematic Review and Meta-Analysis of the Literature
Objective: It is currently unclear whether carotid artery stenting (CAS) is as safe as carotid endarterectomy (CEA) for patients with notable asymptomatic stenosis. The aim of this study was to update a systematic review and meta-analysis of trials comparing CAS with CEA previously performed, showing a moderate certainty of evidence in favour of CEA regarding 30 day stroke or death rates.1
Source: European Journal of Vascular and Endovascular Surgery - May 1, 2023 Category: Surgery Authors: L. Alexopoulou-Prounia, S.K. Kakkos, I. Kakisis, G. Geroulakos Source Type: research

Similar 30 Day Clinical Outcomes After Carotid Artery Stenting By Different Medical Specialities: Analysis From a Large, Multicentre, European Roadsaver Study
Objective: Carotid artery disease treatment options include optimal medical therapy, surgical carotid endarterectomy (CEA), and endovascular carotid artery stenting (CAS). Clinical trials from the past two decades, comparing CEA with CAS reveal higher periprocedural (up to 30 days) risk of stroke or death with CAS. The higher risk is primarily noted in symptomatic patients (> 70 years old), while in younger and/or asymptomatic patients CEA and CAS outcomes are more comparable.1 Contemporary CAS is carried out by operators of different specialties, including angiologists, (neuro)radiologists, cardiologists, and vascular sur...
Source: European Journal of Vascular and Endovascular Surgery - May 1, 2023 Category: Surgery Authors: A. Schwindt, The Roadsaver Investigators O.B.O. Source Type: research

Differential expression profile of miRNAs between stable and vulnerable plaques of carotid artery stenosis patients
Genes Genet Syst. 2023 Apr 28. doi: 10.1266/ggs.22-00123. Online ahead of print.ABSTRACTPlaque vulnerability is associated with the degree of carotid artery stenosis (CS) and the risk of stroke. MicroRNAs (miRNAs) exert critical functions in disease progression, although only a few miRNAs have been well identified in CS. Therefore, this study aimed to investigate the differential expression profile of miRNAs and their potential functions in plaques of CS patients. Three CS patients with stable plaques and three patients with vulnerable plaques who underwent carotid endarterectomy were enrolled in this study. Differentially...
Source: Genes and Genetic Systems - April 30, 2023 Category: Genetics & Stem Cells Authors: Ying Deng Shuai Jiang Xueguang Lin Bo Wang Bo Chen Jindong Tong Weijun Shi Bo Yu Jingdong Tang Source Type: research