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Role of TLR4 (C1196T) and CD14 (C-260T) Polymorphisms in Development of Ischemic Stroke, Its Subtypes and Hemorrhagic Stroke
AbstractIn the present study, we evaluated the association ofTLR4 andCD14 polymorphisms, i.e. C1196T and C-260T, respectively, with ischemic stroke (n = 700), its subtypes and hemorrhagic stroke (n = 300) in a South Indian population from Telangana. The genotypes were determined using PCR–RFLP, and the strength of association between genotypes and stroke was determined by odds ratio with 95% confidence interval (CI) and chi-square analysis. The results revealed a lack of association forTLR4 variant with ischemic stroke and hemorrhagic stroke, although a significant association was observed with the subtypes extracran...
Source: Journal of Molecular Neuroscience - September 30, 2017 Category: Neuroscience Source Type: research

Challenges and Opportunities in Stroke Nursing Research: Global Views From a Panel of Nurse Researchers
This article reflects panel insights on challenges and opportunities for nurse-led stroke research. DISCUSSION: The research challenges discussed include nursing independence, the processes of informed consent and randomization process, obtaining adequate independent funding, recruiting research subjects, and working with vulnerable groups. The major opportunities to leverage and improve stroke nursing research include facilitating the nurse investigator role, information digitalization, improving health literacy, and collaboration between nurse researchers. SUMMARY: We are living in a volatile, uncertain, complex, and amb...
Source: Journal of Neuroscience Nursing - May 13, 2022 Category: Neuroscience Tags: Articles Source Type: research

Anti-NMDAR encephalitis presenting as stroke-like episodes in children: A case series from a tertiary care referral centre from Southern India
Conclusion: Anti-NMDA receptor encephalitis which is a potentially treatable disease should be considered in the differential diagnosis when a child presents with hemiparesis/stroke-like episode.
Source: Journal of Pediatric Neurosciences - June 3, 2022 Category: Neuroscience Authors: Vykuntaraju K Gowda Sukanya Vignesh Balamurugan Natarajan Sanjay K Shivappa Source Type: research

Down syndrome with moyamoya disease: A case series
Pawan Kumar, Inusha Panigrahi, Naveen Sankhyan, Chirag Ahuja, Prasoon K GoyadiJournal of Pediatric Neurosciences 2018 13(2):201-204 Down syndrome (DS), resulting from trisomy 21, is a common cause of mental retardation. Around 20,000 babies with DS are born every year in India. There is an increased risk of cerebral infarction in children with DS, the common causes being thromboembolism secondary to atrioventricular canal defects, right-to-left shunting, myocardial dysmotility, or cardiac valvular abnormalities. Stroke due to other causes can also occur in patients with DS, and one of these is moyamoya disease. This can b...
Source: Journal of Pediatric Neurosciences - July 5, 2018 Category: Neuroscience Authors: Pawan Kumar Inusha Panigrahi Naveen Sankhyan Chirag Ahuja Prasoon K Goyadi Source Type: research

Experience with FRED junior flow diverter in treatment of cerebral aneurysms at or distal to the circle of Willis
Publication date: Available online 23 August 2019Source: Journal of Clinical NeuroscienceAuthor(s): Rajeev Sivasankar, Manish Shrivastava, Uday S. LimayeAbstractThis retrospective study was aimed at assessing our results of endovascular management using the FRED junior flow diverter in cerebral aneurysms at or distal to the circle of Willis. 12 patients with 15 small cerebral vessel aneurysms at or distal to the circle of Willis underwent endovascular treatment using the FRED junior flow diverter at two tertiary care centres in Mumbai, India. 12 of the 15 aneurysms were unruptured, one was treated in an acutely ruptured se...
Source: Journal of Clinical Neuroscience - August 24, 2019 Category: Neuroscience Source Type: research

Cerebral venous sinus thrombosis in children: A study from a tertiary care hospital of eastern India
Conclusion: CVST is an underdiagnosed but important cause of stroke in childhood, occurring most often in the neonatal period. Mortality and morbidity are significant. Infections hyper coagulative disorders are the two primary associations. Magnetic resonance venography is the investigation of choice. Early diagnosis with management along with plan for secondary prevention can save from catastrophic consequences.
Source: Journal of Pediatric Neurosciences - January 19, 2021 Category: Neuroscience Authors: Shubhankar Mishra Ashok K Mallick Geeta Mohanty Priyabrata Nayak Source Type: research

Facilitators and barriers to medication adherence among stroke survivors in India
Publication date: June 2021Source: Journal of Clinical Neuroscience, Volume 88Author(s): S.D. Shani, P.N. Sylaja, P. Sankara Sarma, V. Raman Kutty
Source: Journal of Clinical Neuroscience - April 14, 2021 Category: Neuroscience Source Type: research

Arterial ischemic stroke outcomes in children: Indian perspective
Mahesh KamateJournal of Pediatric Neurosciences 2021 16(3):182-183
Source: Journal of Pediatric Neurosciences - June 3, 2022 Category: Neuroscience Authors: Mahesh Kamate Source Type: research