• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Future heat stroke treatment found in dental pulp stem cells
(Cell Transplantation Center of Excellence for Aging and Brain Repair) Intravenous injections of stem cells derived from human exfoliated deciduous tooth pulp have a protective effect in mice against brain damage from heat stroke. The cells had significantly higher proliferation rates than bone marrow-derived stem cells, were easy to harvest, and expressed growth factors, including vascular endothelial growth factor, that promoted the migration and differentiation of neuronal progenitor cells. The procedure could treat human patients by preventing the neurological damage caused by heat stroke.
Source: EurekAlert! - Medicine and Health - June 5, 2014 Category: Global & Universal Source Type: news

Akt Pathway 'ramp ups' effects of transplanted umbilical cord cells used in stroke therapy
(Cell Transplantation Center of Excellence for Aging and Brain Repair) Researchers found that transplanted human umbilical cord blood cells (HUCBCs) are beneficial in preventing neuron loss when the Akt signaling pathway is activated by HUCBC secretions, and the subsequent Akt activation impacts a specific gene involved in reducing inflammation. A reduction in inflammation helps neural cell survival following stroke. The Akt pathway has been shown to be important because it activates the peroxiredoxin 5 (Prdx5) gene, an antioxidant enzyme that reduces hydrogen peroxide and inflammation.
Source: EurekAlert! - Medicine and Health - February 9, 2015 Category: Global & Universal Source Type: news

Researchers successfully repair stroke-damaged rat brains
(Lund University) Researchers at Lund University in Sweden have succeeded in restoring mobility and sensation of touch in stroke-afflicted rats by reprogramming human skin cells to become nerve cells, which were then transplanted into the rats' brains. The study has now been published in the research journal PNAS.
Source: EurekAlert! - Medicine and Health - April 8, 2020 Category: International Medicine & Public Health Source Type: news

Media advisory: Brain cell injections may quiet epileptic seizures
(NIH/National Institute of Neurological Disorders and Stroke) NIH-funded researchers at the University of California at San Francisco used a mouse model of epilepsy to show that transplanting new born inhibitory nerve cells can quiet seizures.
Source: EurekAlert! - Medicine and Health - May 5, 2013 Category: Global & Universal Source Type: news

Melatonin pre-treatment is a factor that impacts stem cell survival after transplantation
(Cell Transplantation Center of Excellence for Aging and Brain Repair) Melatonin used as a pre-treatment for mesenchymal stem cells, prior to their transplantation into the brains of laboratory animals to repair damage from stroke, helped stem cells survive longer after transplantation. The melatonin pre-treatment greatly increased cell survival when contrasted with previous studies in which 80 percent of transplanted MSCs died within 72 hours of transplantation. Study results demonstrated that the melatonin pre-treated MSCs had enhanced survival under oxidative stimulation by activating the Erk1/2 pathway.
Source: EurekAlert! - Medicine and Health - July 22, 2013 Category: Global & Universal Source Type: news

Dr. Li-Ru Zhao receives 2017 Bernard Sanberg Memorial Award from ASNTR
(Cell Transplantation Center of Excellence for Aging and Brain Repair) Dr. Li-Ru Zhao received the 2017 Bernard Sanberg Memorial Award at the 24th annual meeting of the American Society for Neural Therapy and Repair (ASNTR) for her contributions to stroke, traumatic brain injury, and Alzheimer's disease research.
Source: EurekAlert! - Medicine and Health - May 1, 2017 Category: Global & Universal Source Type: news

Does brain tissue regeneration depend on maturity of stem cells used for transplantation?
(Mary Ann Liebert, Inc./Genetic Engineering News) New research has shown that the success of transplanting stem cells into the brain to regenerate tissue damaged by stroke may depend on the maturity of the neuronal precursor cells used for transplantation.
Source: EurekAlert! - Medicine and Health - September 13, 2017 Category: International Medicine & Public Health Source Type: news

Heart transplants from donors with hepatitis C may be safe and could help decrease organ shortage
(American Heart Association) One-year survival was 90% for adults with severe heart failure who received a heart transplant from a donor with hepatitis C, which was nearly identical to those who received a heart from donors who did not have hepatitis C (91%). Rates of organ rejection, stroke and kidney dialysis were similar between the two groups. More research is needed to assess longer-term results, however, increased use of hearts from donors with hepatitis C could help overcome the national shortage of donor organs.
Source: EurekAlert! - Medicine and Health - January 8, 2020 Category: International Medicine & Public Health Source Type: news