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Total 2601 results found since Jan 2013.

Influence of geography, stroke timing, and weather conditions on transport and workflow times: Results from a longitudinal 5-year Canadian provincial registry
CONCLUSION: Geographic factors and stroke timing were associated with EVT workflow times. However, no association with clinical outcomes was seen, suggesting that EVT patients living remote areas of Saskatchewan have similar benefit from EVT compared to urban areas. Every effort should be made to offer timely EVT to patients from remote areas.PMID:37608547 | DOI:10.1177/15910199231196614
Source: Interventional Neuroradiology - August 23, 2023 Category: Radiology Authors: Nima Kashani Johanna Maria Ospel Nishita Singh Amy Zhou Aravind Ganesh Jessalyn Kathryn Holodinsky Mohammed Almekhlafi Saman Fouladirad Adam Frost Lotus Yang Robert Otani Braedon Newton Amit Persad Sanchea Wasyliw Brett R Graham Gary Hunter Aaron Gardner Source Type: research

Everyday Pain in Middle and Later Life: Associations with Daily and Momentary Present-Moment Awareness as One Key Facet of Mindfulness
This study investigated everyday associations between one key facet of mindfulness (allocating attention to the present moment) and pain. In Study 1, 89 community-dwelling adults (33-88 years; Mage = 68.6) who had experienced a stroke provided 14 daily end-of-day present-moment awareness and pain ratings. In Study 2, 100 adults (50-85 years; Mage = 67.0 years) provided momentary present-moment awareness and pain ratings three times daily for 10 days. Multi-level models showed that higher trait present-moment awareness was linked with lower overall pain (both studies). In Study 1, participants reported less pain on days on ...
Source: Canadian Journal on Aging - August 11, 2023 Category: Geriatrics Authors: Theresa Pauly Anna Nicol Jennifer C Lay Maureen C Ashe Denis Gerstorf Peter Graf Wolfgang Linden Kenneth M Madden Atiya Mahmood Rachel A Murphy Christiane A Hoppmann Source Type: research

What Prohibition Can Teach Us About Drug and Alcohol Policy Today
It’s widely understood today that drinking while pregnant is harmful for the fetus. But the link between alcohol and the health of infants wasn’t as well known in the 1930s, when prohibition was repealed in the U.S. and all sorts of people, pregnant women included, began drinking again.Because prohibition was lifted on a piecemeal basis across the U.S., some counties continued to prohibit alcohol, or stay “dry,” while their neighboring counties were “wet.” Those conditions created what economists call a natural experiment, and made it possible to track the health impacts of maternal drin...
Source: TIME: Health - August 2, 2023 Category: Consumer Health News Authors: Oliver Staley Tags: Uncategorized Public Health Source Type: news

Bedtime versus morning use of antihypertensives in frail continuing care residents (BedMed-Frail): protocol for a prospective, randomised, open-label, blinded end-point pragmatic trial
Introduction BedMed-Frail explores risks and benefits of switching antihypertensives from morning to bedtime in a frail population at greater risk of hypotensive adverse effects. Methods and analysis Design: Prospective parallel randomised, open-label, blinded end-point trial. Participants: Hypertensive continuing care residents, in either long-term care or supportive living, who are free from glaucoma, and using ≥1 once daily antihypertensive. Setting: 16 volunteer continuing care facilities in Alberta, Canada, with eligible residents identified using electronic health claims data. Intervention: All non-opted out elig...
Source: BMJ Open - August 1, 2023 Category: General Medicine Authors: Garrison, S. R., Youngson, E., Perry, D. A., Campbell, F. N., Kolber, M. R., Korownyk, C., Allan, G. M., Green, L., Bakal, J. Tags: Open access, Cardiovascular medicine Source Type: research

O-006 Influence of geolocational factors on patient outcomes post EVT: a population based analysis of transport over long distances in the province of Saskatchewan
ConclusionsReal world geographic factors influence time to treatment, however patient specific factors play a great role in determining patient’s overall outcome during long transports. Factors such as collaterals, occlusion location, and initial aspects are more important than number of kilometers distance travelled or transfer from PSC alone. In an efficient transport system, centralized treatment at the CSC is a viable solution and does not preclude achieving functionally independent outcomes.Abstract O-006 Figure 1Disclosures N. Kashani: None. A. Zhou: None. J. Ospel: None. N. Singh: None. A. Gardner: None. A. Pe...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Kashani, N., Zhou, A., Ospel, J., Singh, N., Gardner, A., Persad, A., Otani, R., Ahmed, U., Peeling, L., Kelly, M. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

Advance consent in acute stroke trials: survey of canadian research ethics board chairs
Can J Neurol Sci. 2023 Jul 24:1-11. doi: 10.1017/cjn.2023.247. Online ahead of print.NO ABSTRACTPMID:37485900 | DOI:10.1017/cjn.2023.247
Source: The Canadian Journal of Neurological Sciences - July 24, 2023 Category: Neurology Authors: Rena Seeger Ubong Udoh Brian Dewar Stuart Nicholls Mark Fedyk Robert Fahed Jeff Perry Michael D Hill Bijoy Menon Richard H Swartz Alexandre Y Poppe Sophia Gocan Jamie Brehaut Katie Dainty Victoria Shepherd Dar Dowlatshahi Michel Shamy Source Type: research

TeleRehabilitation with Aims to Improve Lower extremity recovery in community-dwelling individuals who have had a stroke: protocol for a multisite, parallel group, assessor-blinded, randomised attention-controlled trial
Introduction Telerehabilitation is an accessible service delivery model that may support innovative lower extremity rehabilitation programmes that extend the stroke recovery continuum into the community. Unfortunately, there is limited evidence on the provision of exercises for lower extremity recovery after stroke delivered using telerehabilitation. In response, we developed the TeleRehabilitation with Aims to Improve Lower extremity recovery poststroke (TRAIL) programme, a 4-week progressive exercise and self-management intervention delivered synchronously using video-conferencing technology. Our primary hypothesis is th...
Source: BMJ Open - July 19, 2023 Category: General Medicine Authors: Sakakibara, B. M., Wiley, E., Barclay, R., Bayley, M., Davis, J. C., Eng, J. J., Harris, A., Inness, E. L., MacKay-Lyons, M., Monaghan, J., Pollock, C., Pooyania, S., Schneeberg, A., Teasell, R., Yao, J., Tang, A. Tags: Open access, Health services research Source Type: research

Incidental findings on FDG-PET/CT in large vessel vasculitis
This study aims to determine the number and type of incidental findings detected on positron emission tomography (PET)/CT in a cohort of patients with large vessel vasculitis (LVV). Reports from PET/CT studies along with the medical charts of a cohort of patients with LVV from a Rheumatology clinic in Edmonton, Alberta, Canada, were retrospectively reviewed. Incidental findings from PET/CT, along with follow-up studies and their diagnosis were documented. The data was analyzed with descriptive statistics. The disease activity of 40 patients, with an average age of 65.8  years, was investigated using PET/CT. A statisticall...
Source: Clinical Rheumatology - July 17, 2023 Category: Rheumatology Source Type: research

Impact of body mass index on efficacy and safety of ticagrelor versus clopidogrel in patients with minor stroke or transient ischemic attack
CMAJ. 2023 Jul 10;195(26):E897-E904. doi: 10.1503/cmaj.230262.ABSTRACTBACKGROUND: Body mass index (BMI) may affect the response to platelet P2Y12 receptor inhibitors. We aimed to explore whether BMI influenced the efficacy and safety of ticagrelor and clopidogrel for secondary prevention of minor ischemic stroke or transient ischemic attack (TIA) among patients enrolled in the CHANCE-2 (Ticagrelor or Clopidogrel with Aspirin in High-Risk Patients with Acute Nondisabling Cerebrovascular Events II) trial.METHODS: In a multicentre, randomized, double-blind, placebo-controlled trial, conducted in China, we randomized patients ...
Source: Canadian Medical Association Journal - July 10, 2023 Category: General Medicine Authors: Jia Zhang Anxin Wang Xue Tian Xia Meng Xuewei Xie Jing Jing Jinxi Lin Yilong Wang Zixiao Li Liping Liu Hao Li Yong Jiang Xingquan Zhao Yongjun Wang Source Type: research