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Total 58 results found since Jan 2013.

Neurologic Outcomes of Carotid and Other Emergent Interventions for Ischemic Stroke Over 6  Years With Analysis Enhanced by Machine Learning
Despite continued evolution in treatment, stroke continues to represent one of the most common and debilitating diseases patients suffer. We created a novel machine-learning natural language processing algorithm to assist in performing outcomes research for patients undergoing treatment for stroke. This method enhanced our ability to accurately determine neurologic outcomes for all urgent stroke interventions. Results demonstrate stroke severity and functional neurologic outcomes for all ischemic stroke patients undergoing (1) urgent carotid endarterectomy (uCEA)/urgent carotid artery stenting (uCAS), (2) tissue plasminoge...
Source: Journal of Vascular Surgery - December 20, 2021 Category: Surgery Authors: P. Andrew Rivera, Bethany Jennings, Jeff Burton, Aaron Hayson, Faith Mason, Jaron Pettis, Adam Berenson, W.C. Sternbergh, Samuel Money, Daniel Fort, Hernan Bazan Source Type: research

Neurologic outcomes of carotid and other emergent interventions for ischemic stroke over six years with dataset enhanced by machine learning
Current mainstays of ischemic stroke treatment include the use of thrombolysis (tissue plasminogen activator, tPA), urgent carotid endarterectomy (uCEA) or carotid artery stenting (uCAS), and mechanical endovascular reperfusion/thrombectomy (MER). Scarce data describe the presenting stroke severity and neurologic outcomes for these acute ischemic stroke interventions, alone or in combination. The authors hypothesize that patients undergoing carotid interventions experience better functional neurologic outcomes than other stroke interventions.
Source: Journal of Vascular Surgery - June 24, 2022 Category: Surgery Authors: P. Andrew Rivera, Jeffrey Burton, Aaron Hayson, Bethany Jennings, Gabriel Vidal, W.C. Sternbergh, Daniel Fort, Hernan A. Bazan Source Type: research

Neurologic outcomes of carotid and other emergent interventions for ischemic stroke over 6  years with dataset enhanced by machine learning
The current mainstays of ischemic stroke treatment include the use of thrombolysis (tissue plasminogen activator [tPA]), urgent carotid endarterectomy (uCEA) or urgent carotid artery stenting (uCAS), and mechanical endovascular reperfusion/thrombectomy (MER). Scarce data describe the presenting stroke severity and neurologic outcomes for these acute ischemic stroke interventions, alone or in combination. The authors hypothesize that patients undergoing carotid interventions experience better functional neurologic outcomes than other stroke interventions.
Source: Journal of Vascular Surgery - June 24, 2022 Category: Surgery Authors: P. Andrew Rivera, Jeffrey Burton, Aaron Hayson, Bethany Jennings, Gabriel Vidal, Waldemar C. Sternbergh, Daniel Fort, Hernan A. Bazan Source Type: research

Carotid endarterectomy versus stenting for stroke prevention: what we have and will learn from Carotid Revascularization Endarterectomy versus Stenting Trial
Abstract: The Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) has major implications for the future of carotid revascularization and stroke prevention. The purpose of The William Hinter Harridge Lecture was to discuss the history of carotid revascularization before CREST, to delineate the emergence of carotid artery stenting as an alternative to carotid endarterectomy, analyze the key findings in CREST, and describe the next phase of investigation, CREST-2.
Source: American Journal of Surgery - March 28, 2014 Category: Surgery Authors: Fred A. Weaver Tags: Historian's Lecture Source Type: research

Multimodality imaging of carotid web: A case report and literature review
CONCLUSIONS: carotid web is an under-recognized cause of ischemic stroke. It is easy to be missed or misdiagnosed. Carotid revascularization can effectively prevent recurrent stroke for patients with symptomatic carotid web. Clinicians should strength their learning and understanding of carotid web.PMID:35306924 | DOI:10.1177/17085381221084809
Source: Vascular - March 21, 2022 Category: Surgery Authors: Jie Zhang Yuzhu Yan Weikai Yao Jishuang Liu Li Cui Source Type: research

Safety of Carotid Stenting (CAS) is Based on Institutional Training More than Individual Experience in Large-volume Centres
Background: Operator training is a key factor for the safety of carotid stenting (CAS). Whether institutional practice is associated with improved individual operator outcomes is debated.Objective: To evaluate the effect of the institutional experience on outcomes of new trainees with CAS, a retrospective analysis of a prospectively held database was performed.Methods: The overall study period, 2004–2012, was divided into two sequential time frames: 2004–April 2006 (leaders-team phase) and May 2006–2012 (expanded team phase). In the first frame, a single leader-operators team that first approached CAS and passed the ...
Source: European Journal of Vascular and Endovascular Surgery - March 7, 2013 Category: Surgery Authors: G. Parlani, P. De Rango, F. Verzini, E. Cieri, G. Simonte, A. Casalino, A. Manzone, P. Cao Tags: Carotid Disease Source Type: research

Carotid Intervention Improves Cognitive Function in Patients With Severe Atherosclerotic Carotid Disease
Conclusions: This prospective study showed that carotid intervention improved memory and executive function in patients with the severe carotid occlusive disease. It highlights the cognitive benefit of the carotid intervention in appropriately selected patients.
Source: Annals of Surgery - August 18, 2022 Category: Surgery Tags: Papers of the 141st ASA Annual Meeting Source Type: research

Vascular adhesion protein-1 (VAP-1) in vascular inflammatory diseases
Vasa. 2022 Oct 6. doi: 10.1024/0301-1526/a001031. Online ahead of print.ABSTRACT Vascular adhesion protein-1 (VAP-1) also known as amino oxidase copper containing 3 (AOC3) is a pro-inflammatory and versatile molecule with adhesive and enzymatic properties. VAP-1 is a primary amine oxidase belonging to the semicarbazide-sensitive amine oxidase (SSAO) family, which catalyzes the oxidation of primary amines leading to the production of ammonium, formaldehyde, methylglyoxal, and hydrogen peroxide. VAP-1 is mainly expressed by endothelial cells, smooth muscle cells, adipocytes and pericytes. It is involved in a repertoire of bi...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - October 6, 2022 Category: Surgery Authors: Marianna Danielli Roisin Clare Thomas Lauren Marie Quinn Bee Kang Tan Source Type: research