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Vascular adhesion protein-1 (VAP-1) in vascular inflammatory diseases
Vasa. 2022 Oct 6. doi: 10.1024/0301-1526/a001031. Online ahead of print.ABSTRACT Vascular adhesion protein-1 (VAP-1) also known as amino oxidase copper containing 3 (AOC3) is a pro-inflammatory and versatile molecule with adhesive and enzymatic properties. VAP-1 is a primary amine oxidase belonging to the semicarbazide-sensitive amine oxidase (SSAO) family, which catalyzes the oxidation of primary amines leading to the production of ammonium, formaldehyde, methylglyoxal, and hydrogen peroxide. VAP-1 is mainly expressed by endothelial cells, smooth muscle cells, adipocytes and pericytes. It is involved in a repertoire of bi...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - October 6, 2022 Category: Surgery Authors: Marianna Danielli Roisin Clare Thomas Lauren Marie Quinn Bee Kang Tan Source Type: research

Carotid endarterectomy versus stenting for stroke prevention: what we have and will learn from Carotid Revascularization Endarterectomy versus Stenting Trial
Source: American Journal of Surgery - March 28, 2014 Category: Surgery Authors: Fred A. Weaver Tags: Historian's Lecture Source Type: research

The effect of increasing operator experience on procedure-related characteristics in patients undergoing carotid artery stenting.
Conclusions Endovascular treatment of carotid artery stenosis performed in a single center with the use of a cerebral protection device seems to consist a safe therapeutic choice with acceptable results, within the referenced benchmarks proposed in the latest guidelines. Certain perioperative parameters such as the amount of contrast media used, the fluoroscopy and operation time, seem to decline overtime indicating increasing operator's experience. A number of performed cases above 40 was related to the significant decrease of those parameters and may represent the learning curve of the procedure. PMID: 28142887 [Pub...
Source: Vascular - December 31, 2016 Category: Surgery Authors: Kouvelos G, Koutsoumpelis A, Arnaoutoglou E, Nassis C, Bouris V, Peroulis M, Papadopoulos G, Matsagkas M Tags: Vascular Source Type: research

Haematomas after carotid endarterectomy can be reduced by direct pressure to the neck postoperatively.
Conclusion During recovery from CEA, focused and prolonged pressure by the operating surgeon is a highly effective method of reducing haematoma. PMID: 29909667 [PubMed - as supplied by publisher]
Source: Annals of the Royal College of Surgeons of England - June 18, 2018 Category: Surgery Authors: Saghir R, Humm G, Rix T Tags: Ann R Coll Surg Engl Source Type: research

Use of Machine Learning for Prediction of Patient Risk of Postoperative Complications After Liver, Pancreatic, and Colorectal Surgery
ConclusionMachine learning was used to develop an algorithm that accurately predicted patient risk of developing complications following liver, pancreatic, or colorectal surgery. The algorithm had very  good predictive ability to predict specific complications and demonstrated superiority over other established methods.
Source: Journal of Gastrointestinal Surgery - August 4, 2019 Category: Surgery Source Type: research

Learning Curve for Surgeons Adopting Transcarotid Artery Revascularization Based on the Vascular Quality Initiative-Transcarotid Artery Revascularization Surveillance Project
This study addresses the short learning curve associated with this new procedure. Importantly, patients in the early stages of the learning curve are not at increased risk of stroke, death, or myocardial infarction.
Source: Journal of the American College of Surgeons - October 27, 2019 Category: Surgery Authors: Vikram S. Kashyap, Alexander H. King, Patric Liang, Jens Eldrup-Jorgensen, Grace J. Wang, Mahmoud B. Malas, Brian W. Nolan, Jack L. Cronenwett, Marc L. Schermerhorn Tags: Original Scientific Article Source Type: research

Carotid endarterectomy should be performed first rather than combined with coronary bypass
I read with interest the article addressing timing of carotid endarterectomy (CEA) and coronary artery bypass grafting (CABG)1 since I had just been referred a patient from a cardiac surgeon with the need for both CEA and CABG. I was gratified to learn that in patients with stable angina, performing CEA first compared equally to combined CEA and CABG (CCAB) with regard to both stroke rate and myocardial infarction (MI). From a strictly scheduling standpoint, performing a staged procedure is easier on surgeons and staff.
Source: Journal of Vascular Surgery - November 19, 2020 Category: Surgery Authors: Joseph J. Piotrowski Tags: Letter to the Editor Source Type: research

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