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Total 44 results found since Jan 2013.
New therapy spurs nerve fibers to regrow through scar tissue, transmit signals after spinal cord injury in rodents
Neuroscientists at UCLA, Harvard University and the Swiss Federal Institute of Technology have identified a three-pronged treatment that triggers axons — the tiny fibers that link nerve cells and enable them to communicate — to regrow after spinal cord injury in rodents. Not only did the axons grow through scars, they could also transmit signals across the damaged tissue.If researchers can produce similar results in human studies, the findings could lead to a therapy to regrow axon connections in people living with spinal cord injury, potentially restoring function. Nature publishes the research in its Aug. 29 onl...
Source: UCLA Newsroom: Health Sciences - August 29, 2018 Category: Universities & Medical Training Source Type: news
Statins associated with improvement of rare lung disease
This study suggests that oral statin therapy may be a new approach for patients with autoimmune pulmonary alveolar proteinosis.AUTHORSThe study ’s co-senior authors are Dr. Elizabeth Tarling of UCLA and Dr. Bruce Trapnell of Children’s Hospital Medical Center of Cincinnati, Ohio. Other authors are listed in the journal article.JOURNALThe study was published in the journal Nature Communications. FUNDINGThe National Institutes of Health funded the research.Learn more about the cardiovascular research theme at UCLA.
Source: UCLA Newsroom: Health Sciences - August 17, 2018 Category: Universities & Medical Training Source Type: news
UCLA biologists ‘transfer’ a memory
UCLA biologists report they have transferred a memory from one marine snail to another, creating an artificial memory, by injecting RNA from one to another. This research could lead to new ways to lessen the trauma of painful memories with RNA and to restore lost memories.“I think in the not-too-distant future, we could potentially use RNA to ameliorate the effects of Alzheimer’s disease or post-traumatic stress disorder,” said David Glanzman, senior author of the study and a UCLA professor of integrative biology and physiology and of neurobiology. The team’sresearch is published May 14 in eNeuro, the online journa...
Source: UCLA Newsroom: Health Sciences - May 15, 2018 Category: Universities & Medical Training Source Type: news
UCLA scientists pioneer new method for watching brain cells interact in real time
An advance by UCLA neuroscientists could lead to a better understanding of astrocytes, star-shaped brain cells that are believed to play a key role in neurological disorders like Lou Gehrig ’s, Alzheimer’s and Huntington’s diseases.Reported in Neuron, the new method enables researchers to peer deep inside a mouse ’s brain and watch astrocytes’ influence over the communication between nerve cells in real time. The test relies on fluorescence resonance energy-transfer microscopy, or FRET microscopy, a technique that uses light to measure the tiniest of distances between molecules. The UCLA team focused on astrocyt...
Source: UCLA Newsroom: Health Sciences - April 5, 2018 Category: Universities & Medical Training Source Type: news
Neuroscientists show deep brain waves occur more often during navigation and memory formation
FINDINGSUCLA neuroscientists are the first to show that rhythmic waves in the brain called theta oscillations happen more often when someone is navigating an unfamiliar environment, and that the more quickly a person moves, the more theta oscillations take place — presumably to process incoming information faster.In an unexpected finding, theta oscillations were most prominent in a blind person who relied on a cane to move. The scientists hypothesized that a sightless person explores a strange environment through multiple senses, which would require more brain activity to process the extra sensory input.BACKGROUNDTheta o...
Source: UCLA Newsroom: Health Sciences - December 11, 2017 Category: Universities & Medical Training Source Type: news
Under Affordable Care Act, Americans have had more preventive care for heart health, UCLA study finds
By reducing out-of-pocket costs for preventive treatment, the Affordable Care Act appears to have encouraged more people to have health screenings related to their cardiovascular health,a UCLA study found. Comparing figures from 2006 through 2013, researchers found that more people were screened for diabetes, high cholesterol, cigarette use and high blood pressure — all risk factors for heart disease — after the ACA was implemented than before.But the research, published in the peer-reviewed American Journal of Managed Care, also revealed a disparity between men and women in one key area. Although more men who are at r...
Source: UCLA Newsroom: Health Sciences - November 23, 2017 Category: Universities & Medical Training Source Type: news
UCLA helps many to live long and prosper
In Westwood, more than 100 faculty experts from 25 departments have embarked on anall-encompassing push to cut the health and economic impacts of depression in half by the year 2050. The mammoth undertaking will rely on platforms developed by the new Institute for Precision Health, which will harness the power of big data and genomics to move toward individually tailored treatments and health-promotion strategies.On the same 419 acres of land, researchers across the spectrum, from the laboratory bench to the patient bedside, are ushering in a potentially game-changing approach to turning the body ’s immune defenses again...
Source: UCLA Newsroom: Health Sciences - November 9, 2017 Category: Universities & Medical Training Source Type: news
Spacing out after staying up late? Here ’s why
Ever sleep poorly and then walk out of the house without your keys? Or space out while driving to work and nearly hit a stalled car?A new study led by UCLA ’sDr. Itzhak Fried is the first to reveal how sleep deprivation disrupts brain cells ’ ability to communicate with each other. Fried and his colleagues believe that disruption leads to temporary mental lapses that affect memory and visual perception. Their findings are published online today by Nature Medicine.“We discovered that starving the body of sleep also robs neurons of the ability to function properly,” said Fried, the study’s senior author, a profess...
Source: UCLA Newsroom: Health Sciences - November 6, 2017 Category: Universities & Medical Training Source Type: news
UCLA Health launches pioneering mobile stroke unit with support from L.A. County
Roughly every 40 seconds, someone in the United States will have a stroke. Almost every four minutes, one of those people will die as a result. Against that backdrop, UCLA Health has officially launched the first mobile stroke unit on the West Coast, enabling rapid delivery of brain-saving medications to stroke patients who might otherwise face debilitating delays in treatment. As part of the first phase of a pilot program, the specialized ambulance unit and highly trained personnel began responding in September to select 911 calls in Santa Monica in coordination with the Santa Monica Fire Department. With support from t...
Source: UCLA Newsroom: Health Sciences - October 26, 2017 Category: Universities & Medical Training Source Type: news
UCLA neuroscientists use weak electrical signal to stimulate human brain and improve memory
FINDINGSNeuroscientists at the David Geffen School of Medicine at UCLA have discovered precisely where and how to electrically stimulate the human brain to enhance people’s recollection of distinct memories. People with epilepsy who received low-current electrical pulses showed a significant improvement in their ability to recognize specific faces and ignore simila r ones.Eight of nine patients ’ ability to recognize the faces of specific people improved after receiving electrical pulses to the right side of the brain’s entorhinal area, which is critical to learning and memory. However, electrical stimulation deli...
Source: UCLA Newsroom: Health Sciences - October 24, 2017 Category: Universities & Medical Training Source Type: news
One e-cigarette with nicotine leads to adrenaline changes in nonsmokers ’ hearts
A new UCLA study has found that healthy nonsmokers experienced increased adrenaline levels in their hearts after one electronic cigarette with nicotine.Thefindings are published in Journal of the American Heart Association, the open access journal of the American Heart Association/American Stroke Association.Unlike cigarettes, e-cigarettes, also known as e-cigs, have no combustion or tobacco. Instead, these electronic, handheld devices deliver nicotine with flavoring and other chemicals in a vapor rather than smoke.“While e-cigarettes typically deliver fewer carcinogens than are found in the tar of tobacco cigarette ...
Source: UCLA Newsroom: Health Sciences - September 20, 2017 Category: Universities & Medical Training Source Type: news
Device used to close small hole in heart may protect against recurrent stroke
A device used to close a small hole in the heart may benefit certain stroke patients by providing an extra layer of protection for those facing years of ongoing stroke risk, according to the results of a large clinical trial led by UCLA researchers.“It is a major new treatment option for some people,” said Dr. Jeffrey Saver, director of theUCLA Comprehensive Stroke Center and lead author of the study. However, he added, “Using the device is going to have to be a considered clinical decision between the doctor and the patient about who’s the right person to get it.”Thefindings appear in the Sept. 14 New England Jo...
Source: UCLA Newsroom: Health Sciences - September 14, 2017 Category: Universities & Medical Training Source Type: news
Sleep biology discovery could lead to new insomnia treatments that don ’t target the brain
UCLA scientists report the first evidence that a gene outside the brain controls the ability to rebound from sleep deprivation — a surprising discovery that could eventually lead to greatly improved treatments for insomnia and other sleep disorders that do not involve getting a drug into the brain.The scientists report that increasing the level of Bmal1 — a critical master gene that regulates sleep patterns — in skeletal muscle makes mice resistant to sleep deprivation.“When we first saw the importance of the muscle, we were surprised,” said senior author Ketema Paul, UCLA associate professor of integrative biolo...
Source: UCLA Newsroom: Health Sciences - August 10, 2017 Category: Universities & Medical Training Source Type: news
With a nudge from their wives, three longtime friends get vasectomies in solidarity
Paul Diaz, Basilio Santangelo and John Lambrechts had shared a lot of memorable experiences in their decades of friendship, but going to the doctor to all get vasectomies was one they never expected.The three — each married with two children — had decided with their wives that they didn’t want to continue growing their families. After a pregnancy false alarm, Diaz and his wife, Lisa, agreed that they were happy with their two girls. Lisa brought up the idea of Paul getting a vasectomy, but there wa s a problem.“Like most men,” Diaz said, “I don’t like going to the doctor. I don’t like going to the dentist. ...
Source: UCLA Newsroom: Health Sciences - March 30, 2017 Category: Universities & Medical Training Source Type: news
Scientists identify brain cells involved in Pavlovian response
In his famous experiment, Russian scientist Ivan Pavlov rang a bell each time he fed his dogs. Soon, the dogs began drooling in anticipation when they heard the bell, even before food appeared.Now, a UCLA study has traced the Pavlovian response to a small cluster of brain cells — the same neurons that go awry during Huntington’s disease, Parkinson’s disease and Tourette’s syndrome. Published March 22 in the journal Neuron, the research could eventually help scientists identify new approaches to diagnosing and treating these neurological disorders.“Species survive because they’ve learned how to link sensory cue...
Source: UCLA Newsroom: Health Sciences - March 22, 2017 Category: Universities & Medical Training Source Type: news
