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Specialty: Biochemistry
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Effects of the dimeric PSD-95 inhibitor UCCB01-144 on functional recovery after fimbria-fornix transection in rats
Publication date: Available online 21 September 2017 Source:Pharmacology Biochemistry and Behavior Author(s): Jens Bak Sommer, Anders Bach, Hana Malá, Kristian Strømgaard, Jesper Mogensen, Darryl S. Pickering Pharmacological inhibition of PSD-95 is a promising therapeutic strategy in the treatment of stroke, and positive effects of monomeric and dimeric PSD-95 inhibitors have been reported in numerous studies. However, whether therapeutic effects will generalize to other types of acute brain injury such as traumatic brain injury (TBI), which has pathophysiological mechanisms in common with stroke, is currently uncertain...
Source: Pharmacology Biochemistry and Behavior - September 22, 2017 Category: Biochemistry Source Type: research
