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Beta Amyloid Deposition Is Not Associated With Cognitive Impairment in Parkinson's Disease
In this study, we used a well-validated visual assessment to clinically rate scans as being amyloid positive or negative (38). As there is not an accepted threshold based on standardized centiloid reference regions, we defined an amyloid positivity centiloid cut-off threshold in our sample. Our cut-off (CL = 31.3, SUVR = 1.21) corresponds well to the estimated value proposed by Rowe and colleagues (34) in the context of AD (CL = 25–30), however our estimated threshold may be biased by the low number of Aβ positive patients. Our results suggest a lower prevalence of amyloid-positive PDD individuals than in ...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

A journey through clinic and research
I started to study Medicine at the University of Genoa, Italy more than 20 years ago and I now realize that I was quite far from understanding what ‘Medicine’ really means. After weeks and weeks spent on books during the first year, I understood that becoming a MD not only requires the willingness to help people with health problems, but also strong motivation and dedication to learn a huge amount of notions. In Italy, as it is the case for several other countries, the University courses last 6 years, during which the MD student is fully engaged by individual study, lessons and seminars, exercises, and internships. Wit...
Source: European Heart Journal - March 29, 2021 Category: Cardiology Source Type: research

Real-time reviews of research findings will help policymakers address global crises such as COVID-19
Real-time reviews of research findings could help policymakers address global crises such as COVID-19, saysthis   articlepublished   inNature. Living evidence was first developed by Cochrane and an important recommendation for future health emergencies that came out of the recent Cochrane Convenes meetings. According to scientists writing in the peer-reviewed journal  Nature, policy missteps will continue to overshadow the global response to COVID-19 because policymakers are overwhelmed with rapidly shifting research evidence. Faced with new challenges such as the Omicron variant, decision-makers can ’t keep up wi...
Source: Cochrane News and Events - December 15, 2021 Category: Information Technology Authors: Lydia Parsonson Source Type: news

Cardiac disease prediction using AI algorithms with SelectKBest
AbstractAtherosclerotic cardiovascular disease (ASCVD), which includes coronary heart disease (CHD) and ischemic stroke, is the leading cause of mortality globally. According to the European Society of Cardiology (ESC), 26 million people worldwide have heart disease, with 3.6 million diagnosed each year. Early detection of heart disease will aid in lowering the mortality rate. The lack of diversity in training data and the difficulty in comprehending the findings of complicated AI models are the key issues in current research for heart disease prediction using artificial intelligence. To overcome this, in this paper, cardi...
Source: Medical and Biological Engineering and Computing - September 8, 2023 Category: Biomedical Engineering Source Type: research

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