Beta Amyloid Deposition Is Not Associated With Cognitive Impairment in Parkinson's Disease

Beta Amyloid Deposition Is Not Associated With Cognitive Impairment in Parkinson's Disease Tracy R. Melzer1,2,3†, Megan R. Stark1,2†, Ross J. Keenan1,4, Daniel J. Myall1, Michael R. MacAskill1,2, Toni L. Pitcher1,2,3, Leslie Livingston1,2, Sophie Grenfell1, Kyla-Louise Horne1,2, Bob N. Young1, Maddie J. Pascoe1, Mustafa M. Almuqbel1,2,4, Jian Wang5, Steven H. Marsh6, David H. Miller1,2,7, John C. Dalrymple-Alford1,2,3,8 and Tim J. Anderson1,2,3,9* 1New Zealand Brain Research Institute, Christchurch, New Zealand 2Department of Medicine, University of Otago, Christchurch, New Zealand 3Brain Research New Zealand Rangahau Roro Aotearoa Centre of Research Excellence, Christchurch, New Zealand 4Pacific Radiology Group, Christchurch, New Zealand 5Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China 6Department of Physics and Astronomy, University of Canterbury, Christchurch, New Zealand 7Institute of Neurology, University College London, London, United Kingdom 8Department of Psychology, University of Canterbury, Christchurch, New Zealand 9Department of Neurology, Christchurch Hospital, Christchurch, New Zealand The extent to which Alzheimer neuropathology, particularly the accumulation of misfolded beta-amyloid, contributes to cognitive decline and dementia in Parkinson's disease (PD) is unresolved. Here, we used Florbetaben PET imaging to test for any association between cerebral amyloid deposition and cognitive...
Source: Frontiers in Neurology - Category: Neurology Source Type: research

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Publication date: 15 February 2021Source: Journal of Hazardous Materials, Volume 404, Part AAuthor(s): Zhongyi Zhang, Wen-Xiong Wang, Nengjian Zheng, Yansheng Cao, Hongwei Xiao, Renguo Zhu, Hui Guan, Huayun Xiao
Source: Journal of Hazardous Materials - Category: Environmental Health Source Type: research
Publication date: January 2021Source: Safety Science, Volume 133Author(s): Helen Lingard, Tracy Cooke, Greg Zelic, James Harley
Source: Safety Science - Category: Occupational Health Source Type: research
Authors: Sabet Sarvestani F, Azarpira N Abstract Heart and cerebral infarctions, as two important ischemic diseases, lead to the death of tissues due to inadequate blood supply and high mortality worldwide. These statuses are started via blockage of vessels and depletion of oxygen and nutrients which affected these areas. After reperfusion and restoration of oxygen supply, more severe injury was mediated by multifaceted cascades of inflammation and oxidative stress. microRNAs (miRNAs) as the regulator of biological and pathological pathways can adjust these conditions by interaction with their targets. Also, miRNAs...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
CONCLUSIONS: Immunohistochemistry seems to be a promising option not only in clinical recognition, but also in the selection and monitoring of treatment effects. However, these methods have not yet recommended for routine clinical use. PMID: 33032462 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
CONCLUSION: In this study, no influence of tear substitutes containing different viscosities of hyaluronic acid on the measurement results of optical coherence tomography could be determined. Therefore, 0.1%, 0.2% and 0.3% hyaluronic acid can be applied to the patient to improve the corneal surface before the examination with optical coherence tomography, without influencing the measurement results of optical coherence tomography. PMID: 33036058 [PubMed - as supplied by publisher]
Source: Klinische Monatsblatter fur Augenheilkunde - Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research
Source: European Journal of Sport Science - Category: Sports Medicine Authors: Source Type: research
Authors: White M, Edwards R, Stanley J, Hoek J, Waa AM, Ouimet J, Quah AC, Fong GT PMID: 33032313 [PubMed - in process]
Source: New Zealand Medical Journal - Category: General Medicine Tags: N Z Med J Source Type: research
Authors: Stephens R PMID: 33032312 [PubMed - in process]
Source: New Zealand Medical Journal - Category: General Medicine Tags: N Z Med J Source Type: research
Authors: Havill J, Smales L PMID: 33032311 [PubMed - in process]
Source: New Zealand Medical Journal - Category: General Medicine Tags: N Z Med J Source Type: research
Authors: Nicolson MN, Flett JA PMID: 33032310 [PubMed - in process]
Source: New Zealand Medical Journal - Category: General Medicine Tags: N Z Med J Source Type: research
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