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Total 3962 results found since Jan 2013.

Ischemic Stroke in Evolution: Predictive Value of Perfusion Computed Tomography
Background: Various perfusion computed tomography (PCT) parameters have been used to identify tissue at risk of infarction in the setting of acute stroke. The purpose of this study was to examine predictive value of the PCT parameters commonly used in clinical practice to define ischemic penumbra. The patient selection criterion aimed to exclude the effect of thrombolysis from the imaging data.Methods: Consecutive acute stroke patients were screened and a total of 18 patients who initially underwent PCT and CT angiogram (CTA) on presentation but did not qualify to receive thrombolytic therapy were selected. The PCT images ...
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2013 Category: Neurology Authors: Amir Kheradmand, Marc Fisher, David Paydarfar Tags: Original Articles Source Type: research

Comparison of Computed Tomographic and Magnetic Resonance Perfusion Measurements in Acute Ischemic Stroke: Back-to-Back Quantitative Analysis Clinical Sciences
Conclusions— MRP and CTP can be used interchangeably if one uses Tmax measurement.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Lin, L., Bivard, A., Levi, C. R., Parsons, M. W. Tags: Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Advantages of susceptibility‐weighted magnetic resonance sequences in the visualization of intravascular thrombi in acute ischemic stroke
ConclusionsSWAN was more sensitive than T2* in the visualization of SVS in the intracranial arteries during the acute phase of ischemic stroke. Our study shows that the low number of SVS visualized using T2* in previous studies is probably related to a lack of sensitivity of the sequence, rather than to the nature or age of the thrombus. The greater sensitivity of SWAN seems to be linked to the visualization of SVS in cases of small thrombi.
Source: International Journal of Stroke - October 1, 2014 Category: Neurology Authors: R. Allibert, C. Billon Grand, F. Vuillier, F. Cattin, E. Muzard, A. Biondi, T. Moulin, E. Medeiros Tags: Short Report Source Type: research

Imaging of occlusive thrombi in acute ischemic stroke
Thrombi, or clots, often occlude proximal segments of the cerebral arterial circulation in acute ischemic stroke. Thromboembolic occlusion or thrombi superimposed on atherosclerotic plaque are the principal focus of acute stroke therapies such as thrombolysis or thrombectomy. We review the imaging characteristics of thrombi on multimodal computed tomography and magnetic resonance imaging, angiography, and ultrasonography, summarizing recent studies that facilitate therapeutic decision‐making from these noninvasive studies. Information about the location, size, and imaging characteristics can be ascertained using these te...
Source: International Journal of Stroke - December 26, 2014 Category: Neurology Authors: Gregory G. Gasparian, Nerses Sanossian, Mark S. Shiroishi, David S. Liebeskind Tags: Review Source Type: research

White Matter Ischemic Changes in Hyperacute Ischemic Stroke: Voxel-Based Analysis Using Diffusion Tensor Imaging and MR Perfusion Clinical Sciences
Conclusions— Diffusion tensor imaging-FA was decreased in regions of WM infarction and increased in hypoperfused WM in patients with hyperacute acute ischemic stroke. The significantly increased FA values in the hypoperfused WM with Tmax≥5.4 s are suggestive of early ischemic microstructural changes.
Source: Stroke - January 26, 2015 Category: Neurology Authors: Nael, K., Trouard, T. P., Lafleur, S. R., Krupinski, E. A., Salamon, N., Kidwell, C. S. Tags: CT and MRI, Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Bright Vessel Appearance on Arterial Spin Labeling MRI for Localizing Arterial Occlusion in Acute Ischemic Stroke Brief Reports
Conclusions— The bright vessel appearance on ASL imaging can provide an important diagnostic clue for the detection and localization of arterial occlusion sites in patients with acute ischemic stroke.
Source: Stroke - January 26, 2015 Category: Neurology Authors: Yoo, R.-E., Yun, T. J., Rhim, J. H., Yoon, B.-W., Kang, K. M., Choi, S. H., Kim, J.-H., Kim, J. E., Kang, H.-S., Sohn, C.-H., Han, M. H. Tags: CT and MRI, Acute Cerebral Infarction, Brain Circulation and Metabolism, Computerized tomography and Magnetic Resonance Imaging Brief Reports Source Type: research

Effects of Low-Frequency Repetitive Transcranial Magnetic Stimulation Combined with Intensive Speech Therapy on Cerebral Blood Flow in Post-Stroke Aphasia
Abstract We provided an intervention to chronic post-stroke aphasic patients using low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) guided by a functional magnetic resonance imaging (fMRI) evaluation of language laterality, combined with intensive speech therapy (ST). We performed a single photon emission-computed tomography (SPECT) scan pre- and post-intervention and investigated the relationship between cerebral blood flow (CBF) and language function. Fifty right-handed chronic post-stroke aphasic patients were enrolled in the study. During their 11-day hospital admission, the patients receiv...
Source: Translational Stroke Research - August 7, 2015 Category: Neurology Source Type: research

Patterns and Implications of Intracranial Arterial Remodeling in Stroke Patients Clinical Sciences
Conclusions— Intracranial arteries remodel in response to plaque formation, and posterior circulation arteries have a greater capacity for positive remodeling and, consequently, may more likely elude angiographic detection. Arterial remodeling may provide insight into stroke risk.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Qiao, Y., Anwar, Z., Intrapiromkul, J., Liu, L., Zeiler, S. R., Leigh, R., Zhang, Y., Guallar, E., Wasserman, B. A. Tags: Pathophysiology, Risk Factors, Computerized Tomography (CT), Imaging, Magnetic Resonance Imaging (MRI) Clinical Sciences Source Type: research

Letter by Reale et al Regarding Article, "Clinically Confirmed Stroke With Negative Diffusion-Weighted Imaging Magnetic Resonance Imaging: Longitudinal Study of Clinical Outcomes, Stroke Recurrence, and Systematic Review" Letters to the Editor
Source: Stroke - February 22, 2016 Category: Neurology Authors: Reale, G., Profice, P., Caliandro, P. Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Ischemic Stroke Letters to the Editor Source Type: research

Fibroblast Growth Factor 23 Is Associated With Subclinical Cerebrovascular Damage: The Northern Manhattan Study Clinical Sciences
Conclusions— These cross-sectional community-based data from a diverse urban sample show an association between elevated FGF23 and small vessel disease and magnetic resonance imaging–defined brain infarction in men, independent of chronic kidney disease. Data on elevated FGF23 and subclinical cerebrovascular damage progression are needed.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Wright, C. B., Shah, N. H., Mendez, A. J., DeRosa, J. T., Yoshita, M., Elkind, M. S. V., Sacco, R. L., DeCarli, C., Rundek, T., Silverberg, S., Dong, C., Wolf, M. Tags: Growth Factors/Cytokines, Epidemiology, Risk Factors, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Cerebral Microbleeds and Cortical Superficial Siderosis in Patients Presenting With Minor Cerebrovascular Events Clinical Sciences
Conclusions— CMBs in TIA and minor stroke are moderately common but do not predict recurrence or 90-day outcome. CAA-related transient focal neurological episodes and TIA have overlapping clinical symptoms, suggesting that MRI may be needed for differentiation.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Zerna, C., Modi, J., Bilston, L., Shoamanesh, A., Coutts, S. B., Smith, E. E. Tags: Ischemic Stroke, Transient Ischemic Attack (TIA) Clinical Sciences Source Type: research

Gadolinium Enhancement in Intracranial Atherosclerotic Plaque and Ischemic Stroke: A Systematic Review and Meta-Analysis Stroke
Conclusions Intracranial plaque enhancement on high-resolution vessel wall MRI is strongly associated with ischemic stroke. Evaluation for plaque enhancement on MRI may be a useful test to improve diagnostic yield in patients with ischemic strokes of undetermined etiology.
Source: JAHA:Journal of the American Heart Association - August 14, 2016 Category: Cardiology Authors: Gupta, A., Baradaran, H., Al-Dasuqi, K., Knight-Greenfield, A., Giambrone, A. E., Delgado, D., Wright, D., Teng, Z., Min, J. K., Navi, B. B., Iadecola, C., Kamel, H. Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke, Atherosclerosis Source Type: research

Cerebral Small Vessel Disease Burden Is Increased in Systemic Lupus Erythematosus Clinical Sciences
This study aimed to determine the association between SLE and features on neuroimaging of cerebral small vessel disease (SVD), a risk factor for stroke.Methods—Consecutive patients attending a clinic for SLE were recruited. All patients underwent brain magnetic resonance imaging; had blood samples taken for markers of inflammation, endothelial dysfunction, cholesterol, and autoantibodies; and underwent cognitive and psychiatric testing. The data were compared with sex- and age-matched healthy controls and patients with minor stroke. Features of SVD were measured, a total SVD score calculated, and associations sought with...
Source: Stroke - October 23, 2016 Category: Neurology Authors: Wiseman, S. J., Bastin, M. E., Jardine, C. L., Barclay, G., Hamilton, I. F., Sandeman, E., Hunt, D., Amft, E. N., Thomson, S., Belch, J. F. F., Ralston, S. H., Wardlaw, J. M. Tags: Risk Factors, Imaging, Ischemic Stroke Original Contributions Source Type: research

Infarct Pattern and Collateral Status in Adult Moyamoya Disease Clinical Sciences
Conclusions—In the studied population of adult MMD patients, embolic phenomenon played an important role in ischemic stroke. Therapeutic strategies against thromboembolism, as well as collateral enhancing strategies targeting improvement of hemodynamic status or increased washout of emboli, are warranted.
Source: Stroke - December 22, 2016 Category: Neurology Authors: Dong Yeop Kim, Jeong Pyo Son, Je Young Yeon, Gyeong-Moon Kim, Jong-Soo Kim, Seung-Chyul Hong, Oh Young Bang Tags: Mechanisms, Magnetic Resonance Imaging (MRI), Ischemic Stroke, Moyamoya Original Contributions Source Type: research

Is Unexplained Early Neurological Deterioration After Intravenous Thrombolysis Associated With Thrombus Extension? Clinical Sciences
Conclusions—In this study, unexplained END occurring after thrombolysis was independently associated with susceptibility vessel sign extension, suggesting in situ thrombus extension or re-embolization. These findings strengthen the need to further investigate early post-thrombolysis administration of antithrombotics to reduce the risk of this ominous clinical event.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Pierre Seners, Robert Hurford, Marie Tisserand, Guillaume Turc, Laurence Legrand, Olivier Naggara, Jean-Louis Mas, Catherine Oppenheim, Jean-Claude Baron Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke Original Contributions Source Type: research