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Incidence and predictors of transcatheter aortic valve replacement device emboligenic matter detected by transesophageal echocardiography
This study aimed to investigate the incidence and predictors of emboligenic matter (EM) during TAVR, impact of EM on the procedure, and incidence of symptomatic ischemic stroke post procedure. Among 436 consecutive patients who underwent TF –TAVR, 407 were evaluated in this study. The primary end point was incidence of symptomatic ischemic stroke within 24 h post procedure while taking appropriate preventive measures. Incidence of EM, factors associated with EM, and the impact of EM on the procedure were also investigated. Among the 407 cases, 15 cases (3.7%) of EM were identified but no ischemic stroke occurred in the ...
Source: The International Journal of Cardiovascular Imaging - February 24, 2022 Category: Radiology Source Type: research

Lower Transaortic Flow Rate Is Associated With Increased Mortality in Aortic Valve Stenosis
Conclusions In patients with AS without known cardiovascular disease or diabetes, low transaortic FR was independently associated with higher rates of cardiovascular and all-cause mortality. (An Investigational Drug on Clinical Outcomes in Patients With Aortic Stenosis (Narrowing of the Major Blood Vessel of the Heart) (MK-0653A-043 AM4); NCT00092677)
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - August 7, 2017 Category: Radiology Authors: Saeed, S., Senior, R., Chahal, N. S., Lonnebakken, M. T., Chambers, J. B., Bahlmann, E., Gerdts, E. Tags: Original Research Source Type: research

Long-Term Valve Performance of TAVR and SAVR: A Report From the PARTNER I Trial
Conclusions Longitudinal assessment of the PARTNER (THE PARTNER TRIAL: Placement of AoRTic TraNscathetER Valve Trial) I trial demonstrates that valve performance and cardiac hemodynamics are stable after implantation in both SAPIEN TAVR and SAVR in patients alive at 5 years. (THE PARTNER TRIAL: Placement of AoRTic TraNscathetER Valve Trial [PARTNER]; NCT00530894)
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - January 1, 2017 Category: Radiology Authors: Daubert, M. A., Weissman, N. J., Hahn, R. T., Pibarot, P., Parvataneni, R., Mack, M. J., Svensson, L. G., Gopal, D., Kapadia, S., Siegel, R. J., Kodali, S. K., Szeto, W. Y., Makkar, R., Leon, M. B., Douglas, P. S. Tags: Original Research Source Type: research

Metoprolol Reduces Hemodynamic and Metabolic Overload in Asymptomatic Aortic Valve Stenosis Patients: A Randomized Trial Ventricular Structure and Function
Conclusions— In patients with asymptomatic AS, metoprolol increases systolic ejection time and reduces aortic valve gradients, global afterload, and myocardial oxygen requirements. Thus, metoprolol displays favorable hemodynamic and metabolic effects and could improve outcome in patients with asymptomatic AS. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT02076711.
Source: Circulation: Cardiovascular Imaging - September 27, 2017 Category: Radiology Authors: Hansson, N. H., Sorensen, J., Harms, H. J., Kim, W. Y., Nielsen, R., Tolbod, L. P., Frokiaer, J., Bouchelouche, K., Dodt, K. K., Sihm, I., Poulsen, S. H., Wiggers, H. Tags: Clinical Studies, Metabolism, Valvular Heart Disease, Imaging, Nuclear Cardiology and PET Ventricular Structure and Function Source Type: research

Can stress echocardiography identify patients who will benefit from percutaneous mitral valve repair?
AbstractThe aim of the current study was to investigate whether stress echocardiography improves selection of patients who might have clinical benefit from percutaneous mitral valve repair with the MitraClip. In total, 39 patients selected for MitraClip implantation underwent preprocedural low-dose stress (dobutamine or handgrip) echocardiography from which stroke volume, ejection fraction and MR grade were measured. Outcome after MitraClip implantation was determined by New York Heart Association classification and Quality of Life questionnaires. Clinical benefit from MitraClip treatment was defined as survival and NYHA c...
Source: The International Journal of Cardiovascular Imaging - November 29, 2018 Category: Radiology Source Type: research

Right ventricular longitudinal function is linked to left ventricular filling pressure in patients with repaired tetralogy of fallot
AbstractExperimental data on pulmonary regurgitation has linked right ventricular longitudinal function to left ventricular filling pressure in animals with induced and treated pulmonary regurgitation but this relationship has not been investigated in patients with repaired Tetralogy of Fallot (rToF). The aim of this study was to determine if right ventricular longitudinal function assessed using cardiovascular magnetic resonance (CMR) is associated with left ventricular filling pressure in patients with rToF. A second objective of this study was to determine if direction of septal movement is related to right ventricular ...
Source: The International Journal of Cardiovascular Imaging - September 17, 2022 Category: Radiology Source Type: research

Exploring the Role of Transcatheter Aortic Valve Replacement as the Preferred Treatment for Lower-Risk Patients
The investigators of the NOTION (Nordic Aortic Valve Intervention) trial showed that in an all-comers population of patients with severe aortic stenosis, transcatheter aortic valve replacement (TAVR) using the CoreValve self-expanding bioprosthesis (Medtronic Inc., Minneapolis, Minnesota) yielded similar rates of the composite endpoint of all-cause death, stroke, or myocardial infarction at 1 year compared with surgical bioprosthetic aortic valve replacement (1). Their study is the first to assess in a randomized trial the results of TAVR in a population including a high proportion of patients with low surgical risk (81.8...
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - September 28, 2015 Category: Radiology Source Type: research

Transcatheter Aortic Valve Replacement With Early- and New-Generation Devices in Bicuspid Aortic Valve Stenosis
ConclusionsThe clinical outcomes of TAVR in patients with bicuspid AS were favorable. New-generation devices were associated with less paravalvular leak and, hence, a higher device success rate than early-generation devices. (The  Bicuspid Aortic Stenosis Following Transcatheter Aortic Valve Replacement Registry [Bicuspid TAVR]; NCT02394184)
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - September 5, 2016 Category: Radiology Source Type: research

Incidence, Predictors, and Mid-Term Outcomes of Possible Leaflet Thrombosis After TAVR
Conclusions HALT with reduced leaflet motion was not rare but usually subclinical. Valve hemodynamics and mid-term outcomes were uneventful even without additional anticoagulant therapy in our limited number of cases. Male sex, larger sinus and bioprosthesis size, and elevated D-dimer levels during follow-up were associated with this phenomenon.
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - January 1, 2017 Category: Radiology Authors: Yanagisawa, R., Hayashida, K., Yamada, Y., Tanaka, M., Yashima, F., Inohara, T., Arai, T., Kawakami, T., Maekawa, Y., Tsuruta, H., Itabashi, Y., Murata, M., Sano, M., Okamoto, K., Yoshitake, A., Shimizu, H., Jinzaki, M., Fukuda, K. Tags: Original Research Source Type: research

Comparison of MR flow quantification in peripheral and main pulmonary arteries in patients after right ventricular outflow tract surgery: A retrospective study
ConclusionThe accuracy of PC‐MR in the MPA is reasonable; however, a large random error (precision) is observed that is most pronounced in PS patients. This potential error should be taken into consideration when interpreting MPA flow measurements.Level of Evidence: 3J. Magn. Reson. Imaging 2017.
Source: Journal of Magnetic Resonance Imaging - March 15, 2017 Category: Radiology Authors: Tobias Rutz, Christian Meierhofer, Susanne Naumann, Stefan Martinoff, Peter Ewert, Heiko C. Stern, Sohrab Fratz Tags: Original Research Source Type: research

Prognostic value of left atrial strain in patients with moderate asymptomatic mitral regurgitation
AbstractFor patients with asymptomatic mitral regurgitation (MR), the criteria identifying the groups at higher-risk and their clinical outcome are still uncertain. Therefore, in these patients, optimal time of surgery remains controversial. The purpose of this study was to compare left atrial (LA) strain to other echocardiographic left ventricular (LV) and LA parameters for the prediction of cardiovascular outcomes in patients with moderate asymptomatic MR. We enrolled 395 patients with primary degenerative moderate asymptomatic MR. Exclusion criteria were: history of atrial fibrillation, myocardial infarction, heart fail...
Source: The International Journal of Cardiovascular Imaging - April 9, 2019 Category: Radiology Source Type: research

Improved detection of coarctation of the aorta using speckle tracking analysis of the fetal heart using the last examination prior to delivery.
CONCLUSIONS: Speckle tracking analysis of multiple ventricular measurements may be helpful to separate fetuses that are suspected to have CoA prenatally from those who do not. This article is protected by copyright. All rights reserved. PMID: 32022339 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - February 4, 2020 Category: Radiology Authors: DeVore GR, Haxel C, Satou G, Sklansky M, Pelka MJ, Jone PN, Cuneo BF Tags: Ultrasound Obstet Gynecol Source Type: research

Echocardiographic L-wave as a prognostic indicator in transcatheter aortic valve replacement
This study applies L-wave measurements of mid-diastolic trans-mitral flow. Although considered to be a marker of elevated filling pressure or delayed myocardial relaxation, its clinical and prognostic value is yet to be completely elucidated. It has been shown that transcatheter aortic valve replacement (TAVR) induces reverse remodeling and improves diastolic function and prognosis in patients with severe aortic stenosis (AS). Our purpose was to evaluate the prognostic value of L-wave following TAVR. We examined clinical and echocardiographic data of patients undergoing TAVR. L-Wave presence and velocity were recorded at b...
Source: The International Journal of Cardiovascular Imaging - September 15, 2020 Category: Radiology Source Type: research

Inadequately low left ventricular mass in patients with significant aortic stenosis predicts favourable prognostic outcomes
AbstractIn patients with significant aortic stenosis (AS), the prognostic effect of the increase in left ventricular mass (LVM) in relation to one ’s hemodynamic load has been described. Inappropriately high LVM has been shown to predict adverse cardiovascular events. However, little is known about the prognostic impact of inadequately low LVM (i-lowLVM) in patients with significant AS. I-lowLVM was defined as the measured LVM <  73% of the predicted LVM based on sex, stroke work and height from the reference adult population, used in previous established studies. For outcome analysis, the end-point was defined a...
Source: The International Journal of Cardiovascular Imaging - January 16, 2021 Category: Radiology Source Type: research

Treatment of secondary mitral regurgitation by transcatheter edge-to-edge repair using MitraClip
AbstractTranscatheter edge-to-edge repair (TEER) is becoming the standard invasive treatment for ventricular functional mitral regurgitation (MR). It is necessary to determine the severity of MR before treatment with MitraClip; however, the severity of secondary MR is usually underestimated compared with that of primary MR and varies temporally. Therefore, to accurately determine the severity of MR, it is important to correctly use the algorithm of the guidelines for valvular heart disease and aggressively perform stress echocardiography. Before performing TEER, the difficulty of the procedure should be evaluated. First, m...
Source: Journal of Medical Ultrasonics - June 16, 2022 Category: Radiology Source Type: research

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