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Total 4147 results found since Jan 2013.

'Majority' of stroke patients might have undiagnosed attention disorders
The majority of stroke patients may have attention disorders, most of which are not diagnosed, according to a study published in the journal Neurology. Researchers from Imperial College London in the UK analyzed 110 patients who were being treated for stroke at London's Charing Cross Hospital, alongside 62 participants who had not suffered from stroke. Five of the stroke patients had already been diagnosed with an attention disorder called "neglect" - a deficit of attention and awareness in one side of the body...
Source: Health News from Medical News Today - August 28, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Stroke Outcomes of Japanese Patients With Major Cerebral Artery Occlusion in the Post-Alteplase, Pre-MERCI Era
This study examined outcomes of patients with acute ischemic stroke (AIS) with major cerebral artery occlusion after the approval of intravenous recombinant tissue-type plasminogen activator (IV rt-PA) but before approval of the MERCI retriever. We retrospectively enrolled 1170 consecutive patients with AIS and major cerebral artery occlusion (496 women; mean age, 73.9 ± 12.3 years) who were admitted within 24 hours after the onset of symptoms to 12 Japanese stroke centers between October 2005 and June 2009. Cardioembolism was a leading cause of AIS in this group (68.2%). The occlusion sites of the major cerebral arteries...
Source: Journal of Stroke and Cerebrovascular Diseases - June 21, 2012 Category: Neurology Authors: Kaoru Endo, Masatoshi Koga, Nobuyuki Sakai, Hiroshi Yamagami, Eisuke Furui, Yasushi Matsumoto, Yoshiaki Shiokawa, Shinichi Yoshimura, Yasushi Okada, Jyoji Nakagawara, Toshio Hyogo, Yasuhiro Hasegawa, Hisashi Nagashima, Toshiyuki Fujinaka, Akio Hyodo, Tomo Tags: Original Articles Source Type: research

Endovascular therapeutic hypothermia for acute ischemic stroke: ICTuS 2/3 protocol
Therapeutic hypothermia improves neurological outcome after out‐of‐hospital cardiac arrest or neonatal hypoxic–ischemic injury. Although supported by preclinical evidence, therapeutic hypothermia for acute stroke remains under study. In the Intravascular Cooling in the Treatment of Stroke (ICTuS) trial, awake stroke patients were successfully cooled using an endovascular cooling catheter and a novel antishivering regimen. In the ICTuS‐L study, the combination of endovascular hypothermia and thrombolysis proved feasible; while hypothermia was associated with no increased risk of bleeding complications, there was an ...
Source: International Journal of Stroke - November 10, 2013 Category: Neurology Authors: Patrick D. Lyden, Thomas M. Hemmen, James Grotta, Karen Rapp, Rema Raman Tags: Protocols Source Type: research

Thrombolysis for Acute Ischemic Stroke: Do Patients Treated Out of Hours Have a Worse Outcome?
Introduction: Previous studies on the impact of nonworking hours (NWH) have produced conflicting results. We aimed to compare the time to treatment with thrombolysis between NWH and working hours (WH) at an Australian comprehensive stroke center.Materials and Methods: All acute ischemic stroke patients treated with intravenous alteplase (IV-alteplase) from January 2003 to December 2011 at the Royal Melbourne Hospital were included. Data collected included demographics, serial time points (including onset, presentation to emergency department, neuroimaging, and thrombolysis), and clinical outcomes (modified Rankin Scale [mR...
Source: Journal of Stroke and Cerebrovascular Diseases - April 30, 2013 Category: Neurology Authors: Kun Fang, Leonid Churilov, Louise Weir, Qiang Dong, Stephen Davis, Bernard Yan Tags: Original Articles Source Type: research

Socioeconomic Disparities in the Utilization of Mechanical Thrombectomy for Acute Ischemic Stroke
We examined the utilization rates of mechanical thrombectomy by race/ethnicity (white, black, Hispanic, and Asian/Pacific Islander), income quartile (first, second to third, and fourth), and insurance status (Medicare, Medicaid, self-pay, and private). We also studied thrombectomy utilization rates at hospitals that performed thrombectomy.Results: From 2006 to 2010, 2,087,017 patients were hospitalized with a primary diagnosis of acute ischemic stroke; 8946 patients (.4%) received mechanical thrombectomy. Compared with white patients, black patients had significantly lower rates of overall mechanical thrombectomy utilizati...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Waleed Brinjikji, Alejandro A. Rabinstein, Harry J. Cloft Tags: Original Articles Source Type: research

Earlier thrombolytic treatment is associated with better outcomes following acute ischaemic stroke
Commentary on Saver JL, Fonarow GC, Smith EE, et al.. Time to treatment with intravenous tissue plasminogen activator and outcome from acute ischaemic stroke, JAMA 2013;309:2480–8. Implications for practice and research Optimisation is necessary in public education and hospital triage of the identification of factors such as arrival by ambulance and the importance of requesting emergency medical services (EMS) at scene of the stroke occurrence.1 The results of previous studies suggest that a disparity, observed between hospital-based outcomes for admissions that presented during regular hours and off hours, is not se...
Source: Evidence-Based Nursing - September 15, 2014 Category: Nursing Authors: Ullah, N., Thompson, M. J., Qureshi, A. I. Tags: Adult nursing, Drugs: cardiovascular system, Stroke Source Type: research

Paramedics may be first line of treatment for stroke
There is no time to waste when it comes to stroke. The more time that passes between stroke onset and treatment, the worse the outcome is for the patient. A study designed to test the benefits of early administration of magnesium sulfate suggests that stroke patients may not have to wait until they get to the hospital for treatment — paramedics may be able to start therapy as soon as stroke is suspected.
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - February 4, 2015 Category: Neurology Source Type: news

Implementation of a Stroke Registry Is Associated with an Improvement in Stroke Performance Measures in a Tertiary Hospital in Mexico
Stroke registries provide a simple way for improving patient care, and its use has been associated with a better adherence to the published guidelines. Few Latin American countries had established stroke registries. Our study is the first in Mexico to report the effects of implementing a stroke registry. To determine if the implementation of a systematized registry is associated with an improved adherence to the performance measures.
Source: Journal of Stroke and Cerebrovascular Diseases - February 10, 2015 Category: Neurology Authors: Ana Lucia Herrera, Fernando Góngora-Rivera, Walter Muruet, Héctor Jorge Villarreal, Mildred Gutiérrez-Herrera, Lena Huerta, Diana Carrasco, Anally Soto-García, Meztli Espinosa-Ortega, GECEN Investigators Source Type: research

Telestroke: Solid support for virtual acute stroke care
IV recombinant tissue plasminogen activator (rtPA) within 4.5 hours of symptom onset has been established as an effective therapy for acute ischemic stroke.1 Over the past 2 decades, systems of care and quality assurance teams have developed to ensure that all potentially eligible patients receive IV rtPA in a timely and effective manner.2 Many neurologists cannot arrive rapidly to the emergency department for in-person acute stroke assessment, and many rural areas lack 24/7 coverage by neurologists. Telemedicine has brought neurologic expertise through real-time audiovisual technical link to the emergency department for a...
Source: Neurology - September 25, 2016 Category: Neurology Authors: Demaerschalk, B. M., Levine, S. R. Tags: Outcome research, All Cerebrovascular disease/Stroke, Clinical trials Systematic review/meta analysis EDITORIALS Source Type: research

Early Mortality and Associated Factors among Patients with Stroke Admitted to a Large Teaching Hospital in Tanzania
Stroke is a major cause of death worldwide and 85.5% of stroke deaths occur in low- and middle-income countries due to stroke. The aim of this study was to investigate correlates and predictors of 30-day mortality in stroke patients in urban Tanzania.
Source: Journal of Stroke and Cerebrovascular Diseases - November 28, 2016 Category: Neurology Authors: Kigocha Okeng'o, Pilly Chillo, William K. Gray, Richard W. Walker, William Matuja Source Type: research

Renal Dysfunction Is Associated With Poststroke Discharge Disposition and In-Hospital Mortality Clinical Sciences
Background and Purpose—Kidney disease is a frequent comorbidity in patients presenting with acute ischemic stroke. We evaluated whether the estimated glomerular filtration rate (eGFR) on admission is associated with poststroke in-hospital mortality or discharge disposition.Methods—In this cohort study, data from ischemic stroke patients in Get With The Guidelines–Stroke linked to fee-for-service Medicare data were analyzed. The Modification of Diet in Renal Disease study equation was used to calculate the eGFR (mL/min/1.73 m2). Dialysis was identified by International Classification of Diseases, Ninth Revision codes....
Source: Stroke - January 22, 2017 Category: Neurology Authors: Nada El Husseini, Gregg C. Fonarow, Eric E. Smith, Christine Ju, Lee H. Schwamm, Adrian F. Hernandez, Phillip J. Schulte, Ying Xian, Larry B. Goldstein Tags: Mortality/Survival, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Features of Patients Aged 80 Years or Older with Embolic Stroke of Undetermined Source
In this study, we investigated the features of this condition in patients greater than or equal to 80 years of age. Methods: All patients with acute ischemic stroke in our hospital underwent diffusion-weighted imaging, magnetic resonance angiography, T2-weighted imaging, and fluid-attenuated inversion recovery sequence imaging. Embolic stroke of undetermined source was defined as a radiologically confirmed nonlacunar brain infarct on diffusion-weighted imaging without (1) extracranial or intracranial atherosclerosis causing greater than or equal to 50% luminal stenosis in arteries supplying the ischemic area, (2) major-ris...
Source: Journal of Stroke and Cerebrovascular Diseases - October 24, 2018 Category: Neurology Authors: Tomonori Iwata, Kazunari Honma, Hideyuki Hanano, Ayana Kadokura, Eiichiro Nagata, Shunya Takizawa Source Type: research

Early Magnetic Resonance Imaging Decreases Hospital Length of Stay in Patients with Ischemic Stroke
Imaging modalities are important part of stroke evaluation. Noncontrast head computed tomography (CT) is the initial imaging modality in acute stroke and although important to rule out acute hemorrhage and making a decision on thrombolytic treatment, ischemic changes may not be visible on CT for up to 24 hours. Magnetic resonance imaging (MRI) brain is an invaluable tool to confirm an ischemic stroke and facilitates stroke evaluation. Objective of this study was to investigate the correlation between time to MRI and length of hospital stay.
Source: Journal of Stroke and Cerebrovascular Diseases - November 3, 2018 Category: Neurology Authors: Bharti Manwani, Subhendu Rath, Nora S. Lee, Ilene Staff, Christoph Stretz, Janhavi Modak, Pasquale F. Finelli Source Type: research

Sleep Apnea-Predictor of Functional Outcome in Acute Ischemic Stroke
This study was conducted in Kasturba Medical College (KMC) hospital, Manipal, India, between May 2015 and August 2016.
Source: Journal of Stroke and Cerebrovascular Diseases - December 14, 2018 Category: Neurology Authors: Radhika Nair, Kurupath Radhakrishnan, Aparajita Chatterjee, Shankar P. Gorthi, Varsha A. Prabhu Source Type: research

Reliability of the Acutely Estimated Premorbid Modified Rankin Scale for Stroke Treatment Decision Making
Background: Premorbid functional status is an important factor in acute stroke treatment decision making. Determining the modified Rankin Score (mRS) accurately may be difficult due to deficits from stroke and lack of collateral information in the acute setting. Data on the reliability of the premorbid mRS in “real-world” practice outside of clinical trial or registry settings are limited. Methods: A retrospective study at a high volume academic primary stroke center. For patients with acute ischemic stroke treated with alteplase between July 2012 and July 2016, hospital electronic records were revie wed for detailed i...
Source: Journal of Stroke and Cerebrovascular Diseases - January 9, 2019 Category: Neurology Authors: WenWen Zhang, Skye Coote, Tanya Frost, Helen M. Dewey, Phillip M. Choi Source Type: research