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Drug: Aspirin

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Total 3663 results found since Jan 2013.

Clinical Updates on Antiplatelet Therapy for Secondary Prevention in Acute Ischemic Stroke
Acta Neurol Taiwan. 2023 Sep 30;32(3):138-144.ABSTRACTAntiplatelet therapy is the first-line management for noncardioembolic transient ischemic attack (TIA) and acute ischemic stroke (IS). Herein, we review the safety and efficacy of antiplatelet therapies in patients with IS and TIA, primarily focusing on the acute stage. We discuss current antiplatelet monotherapy and the factors influencing efficacy and continuation rate according to clinical trial data. Aspirin remains the most commonly used first-line antiplatelet agent for preventing noncardioembolic stroke recurrence, and clopidogrel, cilostazol, and ticagrelor are ...
Source: Acta Neurologica Taiwanica - September 7, 2023 Category: Neurology Authors: Tsung-Lin Lee Yu-Ming Chang Pi-Shan Sung Source Type: research

Risk factors and a prediction model for unruptured intracranial aneurysms in patients with ischemic stroke using carotid intima-media thickness and systemic atherosclerosis
ConclusionThe findings revealed that the risk factors for UIA in patients with IS included aspirin use, elevated CRP level, and smaller carotid IMT, and the predictive value of the prediction model was relatively better.
Source: Frontiers in Neurology - August 29, 2023 Category: Neurology Source Type: research

ESC: Adverse Outcomes Increased With Suboptimal Adherence to Aspirin After MI
MONDAY, Aug. 28, 2023 -- Suboptimal adherence to aspirin after myocardial infarction (MI) is associated with an increased risk for recurrent MI, ischemic stroke, or death, according to a study presented at the European Society of Cardiology...
Source: Drugs.com - Pharma News - August 28, 2023 Category: Pharmaceuticals Source Type: news

Fixed dose combination therapies in primary cardiovascular disease prevention in different groups: an individual participant meta-analysis
Conclusions In participants with intermediate cardiovascular risk, FDCs produce larger cardiovascular benefits in older individuals, which appear greater with aspirin. Trial registration number HOPE-3, NCT00468923; TIPS-3, NCT016464137; PolyIran, NCT01271985.
Source: Heart - August 24, 2023 Category: Cardiology Authors: Dagenais, G. R., Pais, P., Gao, P., Roshandel, G., Malekzadeh, R., Joseph, P., Yusuf, S. Tags: Cardiac risk factors and prevention Source Type: research

Skipping Aspirin After Heart Attack Raises Odds for Recurrence
TUESDAY, Aug. 22, 2023 -- If you’ve had a heart attack, your doctor likely told you to take a low-dose aspirin daily to stave off a second heart attack or stroke, but most people don’t follow through with this advice over the...
Source: Drugs.com - Daily MedNews - August 22, 2023 Category: General Medicine Source Type: news

CYP2C19 Loss-of-Function Variants Associated with Long-term Ischemic Stroke Events During Clopidogrel Treatment in the Chinese Population
This study aims to determine whether CYP2C19 loss-of-function (LoF) variants were associated with long-term ischemic stroke risk in Chinese primary care patients treated with clopidogrel. Patients treated with clopidogrel were ascertained from a Chinese Electronic Medical Record linked with biobank for a retrospective cohort study. Their medical information was examined for the period from January 2018 to December 2021. Two CYP2C19 major loss of function variants (*2:rs4244285, *3: rs4986893) were genotyped. The clinical outcome was ischemic stroke event. Cox regression analysis was used to evaluate the association between...
Source: Clinical Pharmacology and Therapeutics - August 22, 2023 Category: Drugs & Pharmacology Authors: Peng Wu Ziqing Liu Zijian Tian Benrui Wu Jian Shao Qian Li Zhaoxu Geng Ying Pan Ke Lu Qiang Wang Tao Xu Kaixin Zhou Source Type: research

Taking aspirin could prevent heart attacks, stroke and early death, study indicates
Aspirin is encouraged by health practitioners following a heart attack, as it can help reduce the formation of life-threatening blood clots.
Source: Daily Express - Health - August 21, 2023 Category: Consumer Health News Source Type: news