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Source: International Journal of Cardiology
Condition: Atrial Fibrillation
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Total 388 results found since Jan 2013.
Trends in stroke incidence after hospitalization for atrial fibrillation in Sweden 1987 to 2006
Conclusion: We found a considerable decrease in risk of ischemic stroke in Sweden in patients without prior stroke and with a first hospital diagnosis of AF. There was an increased risk of hemorrhagic stroke, but because hemorrhagic stroke represented only a small proportion of all strokes, the overall risk of stroke declined.
Source: International Journal of Cardiology - April 5, 2012 Category: Cardiology Authors: Lars G. Olsson, Karl Swedberg, Georg Lappas, Simon Stewart, Annika Rosengren Tags: Original Articles Source Type: research
Comparative assessment of published atrial fibrillation stroke risk stratification schemes for predicting stroke, in a non-atrial fibrillation population: The Chin-Shan Community Cohort Study
Conclusion: Contemporary stroke risk stratification schema used for AF can also be applied to non-AF populations with a similar (modest) predictive value. Given their simplicity (e.g. CHADS2 score), these scores could potentially be used for a ‘quick’ evaluation of stroke risk in non-AF populations, in a similar manner to AF populations.
Source: International Journal of Cardiology - October 16, 2012 Category: Cardiology Authors: Gregory Y.H. Lip, Hung-Ju Lin, Kuo-Liong Chien, Hsiu-Ching Hsu, Ta-Chen Su, Ming-Fong Chen, Yuan-Teh Lee Tags: Original Articles Source Type: research
Relation of renal dysfunction to the increased risk of stroke and death in female patients with atrial fibrillation
Abstract: Background: Female patients with atrial fibrillation (AF) are at increased risk of stroke. It is unclear what contributes to the gender-related differences in stroke and mortality amongst AF patients. This is pertinent since oral anticoagulation use results in a significant reduction in stroke, as well as all-cause mortality.Objective: We investigated gender-related risk factors for stroke and mortality in a cohort of Chinese patients with AF.Methods: We studied 1034 AF patients (27% females, median age 75years) who were followed-up for an average of 1.9years for the principal primary endpoint of ‘ischaemic str...
Source: International Journal of Cardiology - February 1, 2013 Category: Cardiology Authors: Yutao Guo, Haijun Wang, Xiaoning Zhao, Yu Zhang, Dexian Zhang, Jingling Ma, Yutang Wang, Gregory Y.H. Lip Tags: Original Articles Source Type: research
Hyperuricemia and the risk of ischemic stroke in patients with atrial fibrillation — Could it refine clinical risk stratification in AF?
Conclusions: Hyperuricemia was a significant risk factor of stroke which could potentially refine the clinical risk stratification in AF. It deserves a prospective trial to investigate whether it would change the current strategy for stroke preventions using oral anticoagulants.
Source: International Journal of Cardiology - December 2, 2013 Category: Cardiology Authors: Tze-Fan Chao, Chia-Jen Liu, Su-Jung Chen, Kang-Ling Wang, Yenn-Jiang Lin, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Ta-Chuan Tuan, Tzeng-Ji Chen, Hsuan-Ming Tsao, Shih-Ann Chen Tags: Original Articles Source Type: research
Stroke risk and suboptimal thromboprophylaxis in Chinese patients with atrial fibrillation: Would the novel oral anticoagulants have an impact?
Abstract: Background: The risk of stroke associated with atrial fibrillation (AF) is higher in Far Eastern population than in Western population, and warfarin use suboptimal. There is uncertainty whether the novel oral anticoagulants (NOACs) would have a major impact on stroke prevention in Far Eastern populations with AF.Objectives: We investigated current antithrombotic therapy use on stroke and bleeding risk, determinants of warfarin use and performed a modeling analysis of the net clinical benefit of the NOACs (apixaban, dabigatran) in a large cohort of Chinese patients with AF.Methods: We studied 1034 Chinese patients...
Source: International Journal of Cardiology - October 24, 2012 Category: Cardiology Authors: Yutao Guo, Ron Pisters, Stavros Apostolakis, Andrew D. Blann, Haijun Wang, Xiaoning Zhao, Yu Zhang, Dexian Zhang, Jingling Ma, Yutang Wang, Gregory Y.H. Lip Tags: Original Articles Source Type: research
Validation of contemporary stroke and bleeding risk stratification scores in non-anticoagulated Chinese patients with atrial fibrillation
Abstract: Background: Risk stratification schemes assessing stroke and thromboembolism (stroke/TE) and bleeding relating to atrial fibrillation (AF) have largely been derived and validated in Western populations. We assessed risk factors that constitute scores for assessing stroke/TE (CHADS2, CHA2DS2-VASc) and bleeding (HAS-BLED), and the predictive value of these scores in a large cohort of Chinese patients with AF.Methods and results: We studied 1034 AF patients (27.1% female, median age 75; 85.6% non-anticoagulated) with mean follow-up of 1.9years. On multivariate analysis, vascular disease was independently associated ...
Source: International Journal of Cardiology - November 19, 2012 Category: Cardiology Authors: Yutao Guo, Stavros Apostolakis, Andrew D. Blann, Haijun Wang, Xiaoning Zhao, Yu Zhang, Dexian Zhang, Jingling Ma, Yutang Wang, Gregory Y.H. Lip Tags: Original Articles Source Type: research
Characteristics and early and long-term outcome in patients with acute ischemic stroke and low ejection fraction
Conclusions: AIS in patients with low EF is associated with older age, cardiac comorbidities, and more severe clinical presentation. Low EF can identify a subset of AIS patients at high risk of early and long-term functional disability and mortality.
Source: International Journal of Cardiology - November 23, 2012 Category: Cardiology Authors: Haralampos Milionis, Mohamed Faouzi, Maria Cordier, Suzette D'Ambrogio-Remillard, Ashraf Eskandari, Patrik Michel Tags: Original Articles Source Type: research
Percutaneous closure of patent foramen ovale for cryptogenic stroke: A meta-analysis of randomized controlled trials
Conclusions: Currently-available randomized data do not support the use of percutaneous PFO closure for secondary stroke prevention in patients with cryptogenic stroke and PFO. An updated meta-analysis including further data from ongoing RCTs is warranted.
Source: International Journal of Cardiology - July 26, 2013 Category: Cardiology Authors: Joey S.W. Kwong, Yat-Yin Lam, Cheuk-Man Yu Tags: Original Articles Source Type: research
CHA2DS2-VASC-AF2 score accurately predicts moderate-to-severe acute neurological dysfunction in the course of first ever ischemic stroke
Stroke remains one of the leading causes of death and serious long-term disability worldwide [1]. Cardio-embolic stroke, most frequently related to atrial fibrillation (AF), is associated with a high risk of severe psychomotor disability and high stroke-related mortality rate [2]. The commonly applied CHA2DS2-VASC score properly identifies patients at a very low risk of stroke who do not require long-term anticoagulation [3]. Apart from its high predictive value in terms of stroke risk stratification, pre-admission CHA2DS2-VASC score has been recently shown to reflect the actual severity of stroke, once it occurs [4 –5].
Source: International Journal of Cardiology - November 11, 2016 Category: Cardiology Authors: Maciej T. Wybraniec, Maciej Faryan, B łażej Kusz, Anetta Lasek-Bal, Katarzyna Mizia-Stec Tags: Correspondence Source Type: research
Routine preprocedural transesophageal echocardiography might not be necessary for stroke prevention evaluation in AF patients on anticoagulation therapy
Conclusion: The overall periprocedural stroke rate was low (0.3%) in AF patients on anticoagulation therapy. The preprocedural MDCT detected all patients with the LA thrombus. In AF patients with low CHADS2 score, optimal anticoagulation and relatively preserved left ventricular ejection fraction, routine preprocedural TEE in addition to the MDCT might not be necessary to decrease the periprocedural stroke rate.
Source: International Journal of Cardiology - January 25, 2013 Category: Cardiology Authors: Jae-Hyun Han, Dong-Ho Shin, Hye-Jeong Lee, Young Jin Kim, Seung-Hyun Lee, Jaemin Shim, Jae-Sun Uhm, Jong-Youn Kim, Hyuk-Jae Chang, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung Tags: Original Articles Source Type: research
PFO closure vs. medical therapy in cryptogenic stroke or transient ischemic attack: A systematic review and meta-analysis
Conclusions: This meta-analysis does not support PFO closure for secondary prevention with unselected devices in cryptogenic stroke/TIA. In subgroup analysis, selected closure devices may be superior to medical therapy without increasing the risk of new-onset AF, however. This observation should be confirmed in further trials using inclusion criteria for patients with high likelihood of PFO-related stroke recurrence.
Source: International Journal of Cardiology - September 16, 2013 Category: Cardiology Authors: G. Ntaios, V. Papavasileiou, K. Makaritsis, P. Michel Tags: Reviews Source Type: research
Warfarin may reduce risk of ischemic stroke by preventing atrial fibrillation for patients with heart failure and sinus rhythm
As compared with the general population, patients with reduced ejection fraction who are in sinus rhythm are observed with a higher risk for ischemic stroke. This relationship is caused by left ventricular stasis, a systemic hypercoagulable state, and endocardial dysfunction in a situation of impaired left ventricular systolic function . Therefore, the issue whether antithrombotic agents especially aspirin or warfarin could successfully prevent stroke for patients with heart failure and sinus rhythm has been tested in a series of clinical trials. The former two trials (the Warfarin/Aspirin Study in Heart Failure (WASH) tri...
Source: International Journal of Cardiology - July 16, 2012 Category: Cardiology Authors: Gen-Min Lin, Yi-Hwei Li, Lamin .E.S. Jaiteh, Chih-Lu Han Tags: Letters to the Editor Source Type: research
New oral anticoagulants for stroke prevention in left ventricular hypertrabeculation/noncompaction?
Left ventricular hypertrabeculation/noncompaction (LVHT) is a cardiac abnormality of unknown etiology, associated with neuromuscular disorders, and an increased risk of heart failure, arrhythmias, and stroke or embolism (S/E) . We have shown that in 22 of 144 LVHT patients (15%) stroke (n=21) or peripheral embolism (n=1) had occurred. S/E etiology was either cardioembolic (n=14), atherosclerotic (n=5) or undetermined (n=3). Among the patients with cardioembolic S/E, 13/14 had either atrial fibrillation (AF) or systolic dysfunction . In a nested case–control study of patients with severe systolic dysfunction the stroke in...
Source: International Journal of Cardiology - April 19, 2013 Category: Cardiology Authors: Claudia Stöllberger, Josef Finsterer Tags: Letters to the Editor Source Type: research
