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Source: International Journal of Cardiology
Condition: Atrial Fibrillation
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Total 388 results found since Jan 2013.
Screening for atrial fibrillation above age 65 detects an asymptomatic subset at high risk of stroke
Atrial fibrillation (AF) is the most common clinical arrhythmia, and increases risk of stroke 5-fold . Approximately 1/6 strokes are AF-related . These cardio-embolic strokes are severe, and in 18% the underlying AF is previously undiagnosed . Although the occurrence of palpitations is often a guide to the presence of AF, and the symptomatic status of patients with known AF has been well described , the proportion of subjects with incidentally discovered AF who do not have palpitations and are therefore unlikely to present to a physician has not previously been reported. The resulting societal burden of the largely prevent...
Source: International Journal of Cardiology - September 10, 2012 Category: Cardiology Authors: Bishoy Deif, Nicole Lowres, Saul Benedict Freedman Tags: Letters to the Editor Source Type: research
Renal function, P-gp-affecting drugs and new anticoagulants for stroke prevention
New oral anticoagulants (NOAs), like the thrombin-inhibitor dabigatran etexilate or the factor Xa-inhibitor rivaroxaban showed similar efficacy as the vitamin-K-antagonist (VKA) warfarin for stroke prevention in patients with atrial fibrillation (AF) . One of the advantages of the NOAs, compared with VKAs, should be the lack of the necessity for laboratory monitoring and its lower rate of drug- and food interactions. The serum concentration of NOAs, however, is influenced by renal function. Furthermore, NOA-absorption is dependent on the intestinal P-glycoprotein (P-gp)-system, and P-gp activity is influenced by several dr...
Source: International Journal of Cardiology - February 11, 2013 Category: Cardiology Authors: Florian Höllerl, Claudia Stöllberger, Josef Finsterer Tags: Letters to the Editor Source Type: research
Anti-platelet or anti-coagulant agent for the prevention of ischemic stroke in patients with end-stage renal disease and atrial fibrillation—A nation-wide database analyses
The risk/benefit profiles of anti-coagulant or anti-platelet agents in patients with end-stage renal disease (ESRD) and atrial fibrillation (AF) remained unclear. We aimed to investigate the stroke risks in these patients with or without anti-coagulant/anti-platelet therapy by using our national database.
Source: International Journal of Cardiology - October 4, 2014 Category: Cardiology Authors: Jien-Jiun Chen, Lian-Yu Lin, Yao-Hsu Yang, Juey-Jen Hwang, Pau-Chung Chen, Jiunn-Lee Lin Source Type: research
P wave dispersion in cryptogenic stroke: A risk factor for cardioembolism?
Many ischemic strokes (30-40%) occur without a well-defined etiology and are labeled as cryptogenic [1]: sometimes the causes of stroke are unknown, transitory or reversible and therefore difficult to highlight [2]. An example of this kind of causes is paroxysmal atrial fibrillation (PAF), responsible for up to one-third of ischemic strokes: its self-terminating and often asymptomatic nature may lead to its underdiagnosis [3]. EKG recording is not always able to disclose PAF, but the use of prolonged EKG monitoring systems (intermittent, event-triggered, and continuous monitoring procedures by means of externally applied ...
Source: International Journal of Cardiology - April 23, 2015 Category: Cardiology Authors: Maurizio Acampa, Francesca Guideri, Rossana Tassi, Davide Dello Buono, Lorenzo Celli, Lara di Toro Mammarella, Pietro Enea Lazzerini, Giovanna Marotta, Giuseppe Lo Giudice, Paolo D’Andrea, Giuseppe Martini Tags: Letter to the Editor Source Type: research
Effect of antithrombotic and antiplatelet agents for ischemic stroke in atrial fibrillation patients with dialysis
With great interest, we read Chen et al. study about antithrombotic agents in patients with end stage renal disease (ESRD) and atrial fibrillation (AF) [1]. The authors found that anti-platelet or warfarin treatment could not lower the risk of ischemic stroke in patients with ESRD. We have some concerns about this study.
Source: International Journal of Cardiology - April 28, 2015 Category: Cardiology Authors: Chin-Wei Hsu, Yaw-Bin Huang, Chung-Yu Chen Tags: Letter to the Editor Source Type: research
The CHADS and CHADS-VASc scores for predicting ischemic stroke amongst East Asian patients with atrial fibrillation: A systemic review and meta-analysis
Both the CHADS2 and CHA2DS2-VASc scores are well-validated in Western populations for predicting risk of stroke among patients with atrial fibrillation (AF). There is some uncertainty as to which risk score is best to guide optimal anticoagulant therapy among Asian populations with AF.
Source: International Journal of Cardiology - May 20, 2015 Category: Cardiology Authors: Qinmei Xiong, Sisi Chen, Keitaro Senoo, Marco Proietti, Kui Hong, Gregory Y.H. Lip Source Type: research
The CHADS and CHADS-VASc scores for predicting ischemic stroke among East Asian patients with atrial fibrillation: A systemic review and meta-analysis
Both the CHADS2 and CHA2DS2-VASc scores are well-validated in Western populations for predicting risk of stroke among patients with atrial fibrillation (AF). There is some uncertainty as to which risk score is best to guide optimal anticoagulant therapy among Asian populations with AF.
Source: International Journal of Cardiology - May 20, 2015 Category: Cardiology Authors: Qinmei Xiong, Sisi Chen, Keitaro Senoo, Marco Proietti, Kui Hong, Gregory Y.H. Lip Source Type: research
Inadequate anticoagulation by Vitamin K antagonists and major adverse cardiovascular events other than stroke
I read the article by Pastori et al. [1] with great interest. In their artcile, the authors reported that inadequate anticoagulation by Vitamin K Antagonists was found to be associated with Major Adverse Cardiovascular Events (MACE) in patients with atrial fibrillation, and they concluded that time in therapeutic range (TTR) was an independent predictor of MACE in patients with atrial fibrillation. It is known that inadequate anticoagulation by Vitamin K Antagonists is a strong predictor of stroke.
Source: International Journal of Cardiology - October 30, 2015 Category: Cardiology Authors: Mehmet Eyuboglu Tags: Correspondence Source Type: research
Diabetes mellitus and risk of ischemic stroke in patients with heart failure and no atrial fibrillation
The risk of ischemic stroke, systemic thromboembolism, and all-cause death among heart failure patients previously diagnosed with diabetes mellitus is poorly described. We evaluated the risk of these endpoints among heart failure patients without diagnosed atrial fibrillation according to the presence of diabetes mellitus.
Source: International Journal of Cardiology - February 2, 2016 Category: Cardiology Authors: Line Melgaard, Anders Gorst-Rasmussen, Peter Søgaard, Lars Hvilsted Rasmussen, Gregory Y.H. Lip, Torben Bjerregaard Larsen Source Type: research
Association between once- and twice-daily direct oral anticoagulant adherence in nonvalvular atrial fibrillation patients and rates of ischemic stroke
A high degree of adherence to direct oral anticoagulants (DOACs) is essential for reducing the risk of ischemic stroke and systemic embolism in patients with nonvalvular atrial fibrillation (NVAF). This is due to the rapid decline in anticoagulation activity when doses are omitted [1].
Source: International Journal of Cardiology - April 3, 2016 Category: Cardiology Authors: Mark J. Alberts, W. Frank Peacock, Larry E. Fields, Thomas J. Bunz, Elaine Nguyen, Dejan Milentijevic, Jeff R. Schein, Craig I. Coleman Tags: Correspondence Source Type: research
Stroke incidence in patients with cardiac implantable electronic devices remotely controlled with automatic alerts of atrial fibrillation. A sub-analysis of the HomeGuide Study
Remote Monitoring (RM) of cardiac implantable electronic devices (CIEDs) is recommended in management of Atrial Fibrillation (AF), which is a recognized risk factor for thromboembolism. We tried to elucidate whether stroke incidence observed in a large, remotely monitored population was consistent with the CHA2DS2VASc risk profile.
Source: International Journal of Cardiology - June 13, 2016 Category: Cardiology Authors: Renato Pietro Ricci, Diego Vaccari, Loredana Morichelli, Gabriele Zanotto, Leonardo Calò, Antonio D'Onofrio, Antonio Curnis, Ennio C.L. Pisanò, René Nangah, Marco Brieda, Vittorio Calzolari, Donato Melissano, Nicola Rovai, Alessio Gargaro Source Type: research
Inadequate stroke prevention in Korean atrial fibrillation patients in the post-warfarin era
This study aimed to investigate the utilization of anticoagulants since the introduction of DOACs in South Korea.
Source: International Journal of Cardiology - June 24, 2016 Category: Cardiology Authors: Eun Joo Choi, Iyn-Hyang Lee, Nam Kyung Je Source Type: research
Cardiology residents' anticoagulation preferences for stroke prophylaxis in atrial fibrillation patients
Atrial fibrillation (AF) is the most common arrhythmia and carries an increased risk of stroke and mortality [1]. To improve survival and reduce morbidity, there are several international guidelines detailing tools to identify patients requiring treatment and direct best practices for medical, interventional and surgical therapies. Some of the more commonly used guidelines include the European Society of Cardiology's (ESC) 2012 update [2]; the American Heart Association (AHA), American College of Cardiology (ACC) and Heart Rhythm Society's (HRS) 2014 guideline [3]; and the Canadian Cardiovascular Society's (CCS) 2014 guidelines [1].
Source: International Journal of Cardiology - July 29, 2016 Category: Cardiology Authors: Jessica Patzer, Zardasht Oqab, William F. McIntyre, Wilma M. Hopman, Adrian Baranchuk Tags: Correspondence Source Type: research
Meta-analysis of ATRIA versus CHA2DS2-VASc for predicting stroke and thromboembolism in patients with atrial fibrillation
Several studies have compared the discriminative performances of CHA2DS2-VASc and ATRIA scores, but the results are still disputed. Therefore, we aimed to explore their predictive abilities regarding stroke and thromboembolism (TE) risk in AF patients.
Source: International Journal of Cardiology - November 7, 2016 Category: Cardiology Authors: Wengen Zhu, Linghua Fu, Ying Ding, Lin Huang, Zhenyan Xu, Jinzhu Hu, Kui Hong Source Type: research
