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Source: International Journal of Cardiology
Condition: Atrial Fibrillation

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Total 388 results found since Jan 2013.

Resveratrol attenuated homocysteine-induced apoptosis of rat ventricular myocytes
Elevated homocysteine level in the plasma is a new independent important risk factor of ischemic heart diseases, stroke, dementia, Alzheimer's disease, renal failure, osteoporotic fracture, etc. In particular, increasing evidence has revealed a strong association of hyperhyomocystemia with cardiovascular diseases including heart failure, atrial fibrillation and venous thromboembolism, so that serum homocysteine level has been considered as a diagnostic marker of myocardial infraction and an important predictor of mortality for patients with coronary artery diseases (CAD) [1].
Source: International Journal of Cardiology - September 24, 2014 Category: Cardiology Authors: Yu Liu, Qiaojing Liu, Zhina Hu, Qiujia Shen, Hongyan Liang, Xiaofeng Jiang Tags: Letter to the Editor Source Type: research

NT-proBNP in “low risk” patients with atrial fibrillation
Atrial fibrillation (AF) increases the risk of stroke and death and constitutes a significant societal health and economic problem [1,2]. Prediction of thromboembolic risk is most commonly made using a clinical score such as the CHADS2 or CHA2DS2–VASc [3]. N-terminal pro-B-type natriuretic peptide (NT-proBNP) is associated with mortality and cardiovascular events in patients with AF and has been shown to improve risk stratification beyond the CHA2DS2-VASc score [4]. However, the association between NT-proBNP levels and the CHA2DS2-VASc score as well as the prevalence of high NT-proBNP levels indicating high risk in othe...
Source: International Journal of Cardiology - November 7, 2014 Category: Cardiology Authors: Jelena Kornej, Susanne Löbe, Elena Efimova, Daniela Husser, Gerhard Hindricks, Andreas Bollmann Tags: Letter to the editor Source Type: research

Relationship between macular and retinal diseases with prevalent atrial fibrillation — An analysis of the Australian Heart Eye Study
Atrial fibrillation (AF) is the most frequent cardiac arrhythmia, which significantly and independently predicts morbidity and mortality. AF increases overall mortality risk by 40–90%, and may be associated with underlying cardiovascular disorders including stroke and heart failure [1]. Ocular diseases including diabetic retinopathy, age-related macular degeneration (AMD) and retinal vessel calibre changes are also significant predictors of cardiovascular disease and blood pressure [2]. However, their relationship with cardiac arrhythmias such as atrial fibrillation has been relatively unexplored.
Source: International Journal of Cardiology - October 22, 2014 Category: Cardiology Authors: Kevin Phan, Paul Mitchell, Gerald Liew, Sarah B. Wang, Adam J. Plant, Aravinda Thiagalingam, George Burlutsky, Bamini Gopinath Tags: Letter to the Editor Source Type: research

Screening for atrial fibrillation in general practice: A national, cross-sectional study of an innovative technology
To test the use of three lead monitoring as a screening tool for atrial fibrillation (AF) in general practice. AF is responsible for up to a quarter of all strokes and is often asymptomatic until a stroke occurs.
Source: International Journal of Cardiology - November 29, 2014 Category: Cardiology Authors: Gerard Bury, Davina Swan, Walter Cullen, David Keane, Helen Tobin, Mairead Egan, David Fitzmaurice, Crea Carberry, Cecily Kelleher Source Type: research

Thrombosis in Fontan patient on apixaban
We report a case of large thrombus in a 24-year-old male born with double inlet left ventricle in the lateral tunnel Fontan while on apixaban.
Source: International Journal of Cardiology - December 27, 2014 Category: Cardiology Authors: Candida Pinto, Bennett P. Samuel, Christopher Ratnasamy, Joseph J. Vettukattil Source Type: research

Letter by Bassareo regarding the article of Larrson et al. “Incidence of atrial fibrillation in relation to birth weight and preterm birth”
we have read with great interest the commendable article by Larsson and Colleagues, who have demonstrated the association of low birth weight (in men) and high birth weight with an increased risk of the onset of atrial fibrillation. It implies an increased risk of developing an embolic stroke in these subjects as well [1].
Source: International Journal of Cardiology - December 30, 2014 Category: Cardiology Authors: P.P. Bassareo, V. Fanos, G. Mercuro Tags: Letters to the Editor Source Type: research

Vitamin D deficiency and atrial fibrillation
Vitamin D deficiency has been linked with hypertension, coronary artery disease, and stroke, but there is no consensus regarding the possible association between vitamin D deficiency and atrial fibrillation (AF). Vitamin D negatively regulates the renin–angiotensin–aldosterone-system (RAAS), mediates calcium homeostasis, binds to vitamin D receptors on cardiac myocytes, and has antioxidant properties that may reduce levels of reactive oxygen species (ROS) in the atria, which contribute to inflammation and proarrhythmic substrate formation.
Source: International Journal of Cardiology - February 10, 2015 Category: Cardiology Authors: Joseph Thompson, Rynda Nitiahpapand, Prashan Bhatti, Antonios Kourliouros Tags: Review Source Type: research

Primary prophylactic anticoagulation is mandatory if noncompaction is associated with atrial fibrillation or heart failure
Whether patients with left ventricular hypertrabeculation / noncompaction (LVHT) require primary prophylaxis with oral anticoagulation (OAC) to prevent stroke / embolism is unsolved [1]. However, if LVHT is associated with atrial fibrillation (AFIB) / atrial flutter (AFLU), or systolic dysfunction or both, OAC for primary prophylaxis of embolism is mandatory, as illustrated by the following case.
Source: International Journal of Cardiology - February 23, 2015 Category: Cardiology Authors: Josef Finsterer, Claudia Stöllberger Tags: Letter to the editor Source Type: research

Female gender and atrial fibrillation: An association with worse prognosis and outcomes
Females with atrial fibrillation (AF) are at increased risk for ischemic stroke but have been under-represented in AF cohorts. Without anticoagulation, women are at higher risk than men for AF-related thromboembolic events (TE) but results are not consistent [1,2]. Interestingly, vascular complication rates after AF ablation had been recently shown to be also higher in females [3]. Female sex has been included in the CHA2DS2-VASc score for assessing thromboembolic risk, which doubles in women between the ages of 55 and 65, the menopausal period, when estradiol levels decrease by about 60% [4].
Source: International Journal of Cardiology - February 24, 2015 Category: Cardiology Authors: Jelena Kornej, Andreas Bollmann, Gerhard Hindricks, Gregory Y.H. Lip Tags: Letter to the Editor Source Type: research

Hyperuricemia is independently associated with increased risk of atrial fibrillation: A meta-analysis of cohort studies
Atrial fibrillation (AF) is a common cardiovascular disease in the elderly and the most common cardiac arrhythmia [1]. AF increases risk of mortality morbidity, and is associated with risks of a series of subsequent diseases, such as cardiovascular disease, stroke, and impaired cognition [1–3]. A better understanding of AF risk factors is essential for the development of preventive strategies and treatment of AF. Though several studies were published to assess the association between hyperuricemia and AF risk, no consistent results were reported [4–10].
Source: International Journal of Cardiology - February 24, 2015 Category: Cardiology Authors: Xiang Xu, Na Du, Robin Wang, Yangang Wang, Shanglang Cai Tags: Letter to the editor Source Type: research

Association between Neutrophil to Lymphocyte Ratio and Atrial Fibrillation
Neutrophil to Lymphocyte Ratio(NLR) is a ratio of subtypes of leukocyte and has been attracting attention as a significant biomarker of systemic inflammation [1]. Inflammation has a significant role in atherosclerosis [2]. NLR has been shown to be related to adverse outcomes in patients with coronary heart disease (CHD) [3–9] and can independently predict mortality of CHD in an asymptomatic population [9]. Atrial fibrillation (AF) is one of the most common cardiac arrhythmias and increases the risk of stroke and death.
Source: International Journal of Cardiology - March 11, 2015 Category: Cardiology Authors: Zhao Li, Lijun Cui, Junwei Ma, Xianghong Ma, Guangping Li Tags: Letter to the Editor Source Type: research

Atrial Fibrillation and Incident End-Stage Renal Disease: The REasons for Geographic And Racial Differences in Stroke (REGARDS) Study
Atrial fibrillation (AF) is an independent risk factor for end-stage renal disease (ESRD) among persons with chronic kidney disease (CKD), however, the association between AF and incident ESRD has not been examined in the general United States population.
Source: International Journal of Cardiology - March 11, 2015 Category: Cardiology Authors: Wesley T. O’Neal, Rikki M. Tanner, Jimmy T. Efird, Usman Baber, Alvaro Alonso, Virginia J. Howard, George Howard, Paul Muntner, Elsayed Z. Soliman Source Type: research

Psoriasis and risk of atrial fibrillation
Psoriasis is one of the most prevalent T-cell-mediated chronic inflammatory disorders affecting the skin, scalp, nails, and occasionally, joints. The prevalence of psoriasis in the general population ranged from 1% to 4% in population-based studies [1–3]. In recent years, several studies demonstrated that psoriasis is associated with an increased risk of cardiovascular (CV) diseases such as stroke, myocardial infarction (MI), peripheral vascular disease and CV death [4–11]. In a recently published review in the International Journal of Cardiology, Mosca et al.
Source: International Journal of Cardiology - March 18, 2015 Category: Cardiology Authors: Zhiwei Zhang, Guangping Li, Tong Liu Tags: Letter to the Editor Source Type: research

Prothrombotic risk of vitamin K antagonists during the first days of treatment: One more reason to use new oral anticoagulants
In the controlled clinical trials ROCKET AF and ARISTOTLE, which included patients with nonvalvular atrial fibrillation (AF), introduction of warfarin was associated with an excess of ischemic strokes during the first 30days after randomization in vitamin K antagonist (VKA)-naive patients compared with warfarin-experienced patients (4.40/100 patient-years versus 2.86/100 patient-years in ROCKET AF and 5.41/100 patient-years versus 1.42/100 patient-years in ARISTOTLE) [1]. A similar observation was made in the RE-LY trial, in which the risk of ischemic stroke was 0.26% for warfarin versus 0.12% for dabigatran (odds ratio 2....
Source: International Journal of Cardiology - March 19, 2015 Category: Cardiology Authors: Sébastien Gaertner, Elena-Mihaela Cordeanu, Corina Mirea, Dominique Stephan Tags: Letter to the editor Source Type: research

Meta-analysis of Risk of Stroke and Thrombo-Embolism with Rivaroxaban versus Vitamin K antagonists in ablation and cardioversion of atrial fibrillation
: Anticoagulation in cardioversion and ablation of atrial fibrillation is imperative for reducing thrombo-embolic events. Ample information is available about use of warfarin and vitamin K antagonists (VKA) but few trials examine safety and efficacy of rivaroxaban in these procedures. We aim to explore the hypothesis that rivaroxaban causes equal thrombo-embolic and bleeding events when used in atrial fibrillation patients undergoing ablation or cardioversion compared to VKA.
Source: International Journal of Cardiology - March 25, 2015 Category: Cardiology Authors: Ramez Nairooz, Partha Sardar, Maria Pino, Wilbert S. Aronow, Asif Sewani, Debabrata Mukherjee, Hakan Paydak, Waddah Maskoun Source Type: research