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Condition: Stroke
Procedure: PET Scan

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Total 6091 results found since Jan 2013.

Determinants of White Matter Hyperintensity Burden Differ at the Extremes of Ages of Ischemic Stroke Onset
Age is a well-known risk factor for both stroke and increased burden of white matter hyperintensity (WMH), as detected on magnetic resonance imaging (MRI) scans. However, in patients diagnosed with ischemic stroke (IS), WMH volume (WMHv) varies significantly across age groups. We sought to examine the determinants of WMH burden across the ages of stroke onset with the goal to uncover potential age-specific stroke prevention targets.
Source: Journal of Stroke and Cerebrovascular Diseases - January 6, 2015 Category: Neurology Authors: Cathy R. Zhang, Lisa Cloonan, Kaitlin M. Fitzpatrick, Allison S. Kanakis, Alison M. Ayres, Karen L. Furie, Jonathan Rosand, Natalia S. Rost Source Type: research

Comparison of the 2 Most Popular Deconvolution Techniques for the Detection of Penumbral Flow in Acute Stroke Clinical Sciences
Conclusions— Block-circulant single value decomposition seems only significantly beneficial for mean transit time maps in (sub)acute stroke. Tmax is likely the most stable deconvolved parameter for the detection of tissue-at-risk using DSC-MRI.
Source: Stroke - September 28, 2015 Category: Neurology Authors: Zaro-Weber, O., Livne, M., Martin, S. Z., von Samson-Himmelstjerna, F. C., Moeller-Hartmann, W., Schuster, A., Brunecker, P., Heiss, W.-D., Sobesky, J., Madai, V. I. Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging, PET and SPECT Clinical Sciences Source Type: research

Ultra-acute CT perfusion imaging: A stroke in the scanner
A stroke patient with a mild right hemiparesis (NIH Stroke Scale score 4) underwent dual-slab CT perfusion (CTP). In the midst of acquiring the lower CTP slab, she became aphasic and developed a dense right hemiparesis (NIH Stroke Scale score 17). Reconstruction of the CTP into a dynamic CT angiogram demonstrates fragmentation of an internal carotid artery thrombus at the time of clinical worsening (figure 1; video on the Neurology® Web site at Neurology.org). The upper CTP slab, acquired 2 minutes later, provides the earliest known view of the hemodynamics of ischemic stroke in humans. It demonstrates total absence of...
Source: Neurology - November 9, 2015 Category: Neurology Authors: Christensen, S., Obi, C., Albers, G., Lansberg, M. Tags: CT, All Cerebrovascular disease/Stroke, Embolism, Infarction VIDEO NEUROIMAGES Source Type: research

Intra-Arterial Therapy and Post-Treatment Infarct Volumes: Insights From the ESCAPE Randomized Controlled Trial Clinical Sciences
Conclusions— These results support the primary results of the ESCAPE trial and show that the biological underpinning of the success of endovascular therapy is a reduction in infarct volume. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01778335.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Al-Ajlan, F. S., Goyal, M., Demchuk, A. M., Minhas, P., Sabiq, F., Assis, Z., Willinsky, R., Montanera, W. J., Rempel, J. L., Shuaib, A., Thornton, J., Williams, D., Roy, D., Poppe, A. Y., Jovin, T. G., Sapkota, B. L., Baxter, B. W., Krings, T., Silver, F Tags: Imaging, Quality and Outcomes, Ischemic Stroke Clinical Sciences Source Type: research

Neuroimaging Markers of Cognitive Outcome in Children with Perinatal Stroke (I2.002)
Conclusions: As seen in other studies, prognosis of cognitive outcome is difficult and there was no correlation between site of lesion and areas of intellectual deficit. However, there was some indication that loss of more cortical volume, or involvement of the DLPF cortex may be risk factors for intellectual impairment in childhood.Disclosure: Dr. Murias has nothing to disclose. Dr. Kirton has nothing to disclose. Dr. Tariq has nothing to disclose. Dr. Moir has nothing to disclose. Dr. Iaria has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Murias, K., Kirton, A., Tariq, S., Moir, A., Iaria, G. Tags: Stroke in the Elderly and Young: Challenges for the Next Decade Data Blitz Presentations Source Type: research

Neuroimaging Markers of Cognitive Outcome in Children with Perinatal Stroke (P3.256)
Conclusions: As seen in other studies, prognosis of cognitive outcome is difficult and there was no correlation between site of lesion and areas of intellectual deficit. However, there was some indication that loss of more cortical volume, or involvement of the DLPF cortex may be risk factors for intellectual impairment in childhood.Disclosure: Dr. Murias has nothing to disclose. Dr. Kirton has nothing to disclose. Dr. Tariq has nothing to disclose. Dr. Moir has nothing to disclose. Dr. Iaria has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Murias, K., Kirton, A., Tariq, S., Moir, A., Iaria, G. Tags: Child Neurology and Developmental Neurology: Epilepsy, Hypoxia, and Stroke Source Type: research

Multidisciplinar Team Ability to Decrease Door-To-Needle Time in Acute Ischemic Stroke - A Single Center Saudi Experience (P6.053)
Conclusions: Implementation of modified stroke code process utilizing quality improvement paradigm of PDSA cycles have resulted in significant decrease in door-to-needle time for IV thrombolysis. Although, the target DTN of 60 minutes was not reached, the trend is favorable with improved outcomes. Disclosure: Partly presented at 5th Annual KAIMRC Forum, September, 2014, Jeddah, Saudi ArabiaDisclosure: Dr. Khatri has nothing to disclose. Dr. Khathaami has nothing to disclose. Dr. Alhamouieh has nothing to disclose. Dr. Abulaban has nothing to disclose. Dr. Scriven has nothing to disclose. Dr. Tarawneh has nothing to disclos...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Khatri, I., Khathaami, A., Alhamouieh, O., Abulaban, A., Scriven, S., Tarawneh, M., Alrasheed, D., AlSomali, S., Catangui, E., Manalili, C., Ghadalla, A., Alanizi, A., Kojan, S. Tags: Prehospital Stroke Care and Uses of NIHSS Source Type: research

The 'pit-crew model for improving door-to-needle times in endovascular stroke therapy: a Six-Sigma project
Conclusions A protocol-driven process can significantly improve efficiency of care in time-sensitive stroke interventions.
Source: Journal of NeuroInterventional Surgery - April 13, 2016 Category: Neurosurgery Authors: Rai, A. T., Smith, M. S., Boo, S., Tarabishy, A. R., Hobbs, G. R., Carpenter, J. S. Tags: Open access, Ischemic stroke Source Type: research

Evolutional Characterization of Photochemically Induced Stroke in Rats: a Multimodality Imaging and Molecular Biological Study
In conclusion, these characterizations may be highly beneficial to the development of therapeutic strategies for ischemi c stroke.
Source: Translational Stroke Research - November 30, 2016 Category: Neurology Source Type: research

Prediction of Blood-Brain Barrier Disruption and Intracerebral Hemorrhagic Infarction Using Arterial Spin-Labeling Magnetic Resonance Imaging Clinical Sciences
Background and Purpose—Arterial spin-labeling magnetic resonance imaging is sensitive for detecting hyperemic lesions (HLs) in patients with acute ischemic stroke. We evaluated whether HLs could predict blood–brain barrier (BBB) disruption and hemorrhagic transformation (HT) in acute ischemic stroke patients.Methods—In a retrospective study, arterial spin-labeling was performed within 6 hours of symptom onset before revascularization treatment in 25 patients with anterior circulation large vessel occlusion on baseline magnetic resonance angiography. All patients underwent angiographic procedures intended for endovasc...
Source: Stroke - December 22, 2016 Category: Neurology Authors: Takeya Niibo, Hajime Ohta, Shirou Miyata, Ichiro Ikushima, Kazuchika Yonenaga, Hideo Takeshima Tags: Imaging, Magnetic Resonance Imaging (MRI), Blood-Brain Barrier, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Intracranial Carotid Artery Calcification Relates to Recanalization and Clinical Outcome After Mechanical Thrombectomy Clinical Sciences
Conclusions—A larger amount of ICAC before mechanical thrombectomy in acute stroke patients is an indicator of worse postprocedural arterial revascularization and poorer functional outcome.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Maria Hernandez–Perez, Daniel Bos, Laura Dorado, Karliȷn Pellikaan, Meike W. Vernooiȷ, Elena Lopez–Cancio, Natalia Perez de la Ossa, Meritxell Gomis, Carlos Castano, Josep Munuera, Josep Puig, Monica Millan, Antoni Davalos Tags: Computerized Tomography (CT), Imaging, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

Streamlining door to recanalization processes in endovascular stroke therapy
Conclusions This pilot study demonstrates that D2P times can be significantly reduced with a standardized multidisciplinary approach. There was no significant difference in the rate of 3-month good outcome, which is most likely due to the small sample size and confounding baseline patient characteristics.
Source: Journal of NeuroInterventional Surgery - March 15, 2017 Category: Neurosurgery Authors: Aghaebrahim, A., Streib, C., Rangaraju, S., Kenmuir, C. L., Giurgiutiu, D.-V., Horev, A., Saeed, Y., Callaway, C. W., Guyette, F. X., Martin-Gill, C., Pacella, C., Ducruet, A. F., Jankowitz, B. T., Jovin, T. G., Jadhav, A. P. Tags: Ischemic stroke Source Type: research

Recurrent Stroke and Early Mortality in an Urban Medical Unit in Cameroon
Data on stroke mortality in recurrent strokes in the context of limited acute stroke care and secondary stroke prevention within Africa are very scant. We investigated the risk of in-hospital death in patients with recurrent stroke in the medical department of the Yaound é Central Hospital in Cameroon.
Source: Journal of Stroke and Cerebrovascular Diseases - April 14, 2017 Category: Neurology Authors: Alain Lekoubou, Clovis Nkoke, Anastase Dzudie, Andre Pascal Kengne Source Type: research

Collaborative Interventions Reduce Time-to-Thrombolysis for Acute Ischemic Stroke in an Urban, Public Hospital (P4.270)
Conclusions:Targeted, multidisciplinary, collaborative interventions are associated with substantial and significant reductions in time to thrombolysis. Such targeted interventions are effective and feasible in the unique setting of a public safety net hospital.Disclosure: Dr. Threlkeld has nothing to disclose. Dr. Kozak has nothing to disclose. Dr. Cole has nothing to disclose. Dr. Martin has nothing to disclose. Dr. Singh has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Threlkeld, Z., Kozak, B., Cole, S., Martin, C., Singh, V. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Diagnosis of DWI-negative acute ischemic stroke: A meta-analysis
Conclusions: A small but significant percentage of patients with AIS have a negative DWI scan. Patients with neurologic deficits consistent with posterior circulation ischemia have 5 times the odds of having a negative DWI scan compared to patients with anterior circulation ischemia. AIS remains a clinical diagnosis and urgent reperfusion therapy should be considered even when an initial DWI scan is negative.
Source: Neurology - July 17, 2017 Category: Neurology Authors: Edlow, B. L., Hurwitz, S., Edlow, J. A. Tags: MRI, DWI, All Cerebrovascular disease/Stroke, Infarction ARTICLE Source Type: research