• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

How Exercise Shapes You, Far Beyond the Gym
(Photo: Grady Reese) By Bradley Stulberg When I first started training for marathons a little over ten years ago, my coach told me something I've never forgotten: that I would need to learn how to be comfortable with being uncomfortable. I didn't know it at the time, but that skill, cultivated through running, would help me as much, if not more, off the road as it would on it. It's not just me, and it's not just running. Ask anyone whose day regularly includes a hard bike ride, sprints in the pool, a complex problem on the climbing wall, or a progressive powerlifting circuit, and they'll likely tell you the same: A diff...
Source: Healthy Living - The Huffington Post - July 1, 2016 Category: Consumer Health News Source Type: news

Spinal Cord Infarction in Clinical Neurology: A Review of Characteristics and Long-Term Prognosis in Comparison to Cerebral Infarction
Spinal cord stroke is rare accounting for 0.3-1% of all strokes and is classified into upper (cervical) and lower (thoracolumbar) strokes. Patients present with severe deficits but later often show good functional improvement. On admission, younger age, male gender, hypertension, diabetes mellitus and elevated blood glucose indicate more severe spinal cord strokes. Treatment of these risk factors is essential in the acute phase. Biphasic spinal cord strokes are seen in one-fifth of the patients. These present with acute or transient sensory spinal cord deficits often preceded by radiating pain between the shoulders, and sh...
Source: European Neurology - August 3, 2016 Category: Neurology Source Type: research

Self ‐care agency, lifestyle, and physical condition predict future frailty in community‐dwelling older people
Abstract The purpose of this 2 year longitudinal study was to identify the relationship between self‐care agency, lifestyle, physical condition, and frailty among community‐dwelling older people in a rural area of Japan. The participants were 133 older individuals aged 65 years or above. Data collection was conducted via face‐to‐face interviews using self‐administered questionnaires. Background information, such as age, sex, current employment status, family structure, medication use, comorbidities, and knee and lower back pain, were assessed. The definition of frailty was based on the Frailty Checklist. Self...
Source: Nursing and Health Sciences - September 1, 2017 Category: Nursing Authors: Chika Tanimura, Hiromi Matsumoto, Yasuko Tokushima, Junko Yoshimura, Shinji Tanishima, Hiroshi Hagino Tags: RESEARCH ARTICLE Source Type: research

439OA first in human, phase I trial of NP137, a first-in-class antibody targeting netrin-1, in patients with advanced refractory solid tumors
ConclusionsNP137 was well-tolerated, with mild to moderate IRR as the most frequent treatment-related AEs and showed encouraging signs of clinical activity. Updated data will be presented at the meeting.Clinical trial identificationNCT02977195.Legal entity responsible for the studyCentre L éon Bérard.FundingNetris Pharma.DisclosureP. Cassier: Honoraria (self), Research grant / Funding (self), Research grant / Funding (institution), Travel / Accommodation / Expenses: AstraZeneca; Research grant / Funding (institution), Travel / Accommodation / Expenses: BMS; Research grant / Funding (institution), Travel / Accommodation /...
Source: Annals of Oncology - October 1, 2019 Category: Cancer & Oncology Source Type: research

The global burden of disease attributable to high body mass index in 195 countries and territories, 1990 –2017: An analysis of the Global Burden of Disease Study
ConclusionsIn this study, we observed that the number of global deaths and DALYs attributable to high BMI has substantially increased between 1990 and 2017. Successful population-wide initiatives targeting high BMI may mitigate the burden of a wide range of diseases. Given the large variations in high-BMI-related burden of disease by SDI, future strategies to prevent and reduce the burden should be developed and implemented based on country-specific development status.
Source: PLoS Medicine - July 27, 2020 Category: Internal Medicine Authors: Haijiang Dai Source Type: research