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Source: BMJ Open
Condition: Diabetes

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Total 89 results found since Jan 2013.

Distribution of risk factors differs from coronary heart disease and stroke in China: a national population survey
Conclusions The distribution of risk factors for CHD and stroke were substantial differences. More specific prevention and control measures should be formulated according to the distribution differences of risk factors related to CVD.
Source: BMJ Open - November 24, 2022 Category: General Medicine Authors: Li, Y., Yin, L., Shen, Y., Wang, A., Zhou, L., Gao, Y., Li, Y., Lu, J., Shi, S., Tian, C., Xu, Y., Wang, L., on behalf of the China National Stroke Screening Survey investigators Tags: Open access, Public health Source Type: research

Stroke incidence and association with risk factors in women: a 32-year follow-up of the Prospective Population Study of Women in Gothenburg
Conclusions Hypertension, smoking, AF, diabetes and high BMI were associated with increased stroke risk. Low education was associated with stroke. Validation of National Patient Registry diagnoses to increase specified diagnoses improved data quality.
Source: BMJ Open - October 28, 2014 Category: Journals (General) Authors: Blomstrand, A., Blomstrand, C., Ariai, N., Bengtsson, C., Bjorkelund, C. Tags: Open access, Cardiovascular medicine, Epidemiology Research Source Type: research

Prevalence of stroke and associated risk factors: a population-based cross-sectional study from the Qinghai-Tibet Plateau of China
Conclusions The prevalence of stroke, the related risk factors and the detection rate of high-risk individuals were clarified. The prevalence rates of hypertension, overweight or obesity and diabetes in the Qinghai-Tibet Plateau were all higher than the Chinese average. Higher-altitude exposure may be an independent risk factor for stroke.
Source: BMJ Open - November 22, 2022 Category: General Medicine Authors: Li, Z., Hu, Q., Ji, W., Fan, Q. Tags: Open access, Epidemiology Source Type: research

Trends of frequency, mortality and risk factors among patients admitted with stroke from 2017 to 2019 to the medical ward at Kilimanjaro Christian Medical Centre hospital: a retrospective observational study
Conclusion The burden of stroke on individuals and health services is increasing over time, which reflects a lack of awareness on the cause of stroke and effective preventive measures. Prioritising interventions directed towards the reduction of non-communicable diseases and associated complications, such as stroke, is urgently needed.
Source: BMJ Open - July 31, 2023 Category: General Medicine Authors: Moshi, B., Yongolo, N., Biswaro, S. M., Maro, H., Linus, S., Siebert, S., Nkenguye, W., McIntosh, E., Shirima, F., Njau, R. E., Andongolile, A. A., Mwanswila, M. J., Halliday, J. E. B., Krauth, S., Kilonzo, K., Walker, R. W., Temu, G. A., Mmbaga, B. T. Tags: Open access, Cardiovascular medicine Source Type: research

Development and internal validation of a multivariable prediction model for 6-year risk of stroke: a cohort study in middle-aged and elderly Chinese population
Conclusion Our nomogram could be convenient, easy to use and effective prognoses for predicting 6-year risk of stroke in middle-aged and elderly Chinese population.
Source: BMJ Open - July 7, 2021 Category: General Medicine Authors: Yu, Q., Wu, Y., Jin, Q., Chen, Y., Lin, Q., Liu, X. Tags: Open access, Epidemiology Source Type: research

Clinical characteristics, precipitating factors, management and outcome of patients with prior stroke hospitalised with heart failure: an observational report from the Middle East
Conclusions This observational study reports high prevalence of prior stroke in patients hospitalised with HF. Internists rather than cardiologists were the predominant caregivers in this high-risk group. Patients with stroke had higher risk of in-hospital recurrent strokes and long-term mortality rates. Trial registration number NCT01467973.
Source: BMJ Open - April 23, 2015 Category: Journals (General) Authors: Khafaji, H. A. R., Sulaiman, K., Singh, R., AlHabib, K. F., Asaad, N., Alsheikh-Ali, A., Al-Jarallah, M., Bulbanat, B., AlMahmeed, W., Ridha, M., Bazargani, N., Amin, H., Al-Motarreb, A., AlFaleh, H., Elasfar, A., Panduranga, P., Al Suwaidi, J. Tags: Open access, Cardiovascular medicine Research Source Type: research

Association between fasting blood glucose levels and stroke events: a large-scale community-based cohort study from China
Conclusions Higher FBG level was independently associated with an increased risk of stroke in Chinese adults, especially significant in women.
Source: BMJ Open - August 18, 2021 Category: General Medicine Authors: Zhang, Y., Gu, S., Wang, C., Liu, D., Zhang, Q., Yang, M., Zhou, Z., Zuo, H. Tags: Open access, Public health Source Type: research

Impacts of type 2 diabetes mellitus and hypertension on the incidence of cardiovascular diseases and stroke in China real-world setting: a retrospective cohort study
Conclusion T2DM and HTN were strongly associated with combined VE and stroke risk; however, the HTN-only group had a higher combined VE and stroke risk than the T2DM-only group.
Source: BMJ Open - November 29, 2021 Category: General Medicine Authors: Liu, Y., Li, J., Dou, Y., Ma, H. Tags: Open access, Diabetes and Endocrinology Source Type: research

Assessment of mental health trajectories before and after myocardial infarction, atrial fibrillation or stroke: analysis of a cohort study in Tromso, Norway (Tromso Study, 1994-2016)
Conclusion The study indicates that mental health problems among individuals with myocardial infarction, atrial fibrillation and stroke may have started to develop several years before the cardiovascular event and suggests that successful CVD rehabilitation may need to consider previous life factors. Future research is recommended to examine whether health promotion measures in a general population also create mental health resilience after a CVD event.
Source: BMJ Open - April 1, 2022 Category: General Medicine Authors: Lorem, G. F., Opdal, I. M., Wilsgaard, T., Schirmer, H., Lochen, M.-L., Olsen, I. P., Steigen, T., Rognmo, K. Tags: Open access, Mental health Source Type: research

Body mass index in early and middle adult life: prospective associations with myocardial infarction, stroke and diabetes over a 30-year period: the British Regional Heart Study
Conclusions Higher BMI at 21 years of age is associated with later diabetes incidence but not MI or stroke, while higher BMI in middle age is strongly associated with all outcomes. Early obesity prevention may reduce later type 2 diabetes risk, more than MI and stroke.
Source: BMJ Open - September 15, 2015 Category: Journals (General) Authors: Owen, C. G., Kapetanakis, V. V., Rudnicka, A. R., Wathern, A. K., Lennon, L., Papacosta, O., Cook, D. G., Wannamethee, S. G., Whincup, P. H. Tags: Open access, Cardiovascular medicine, Epidemiology, Public health, Diabetes and Endocrinology Research Source Type: research

Development and internal validation of a clinical risk score for in-hospital mortality after stroke: a single-centre retrospective cohort study in Northwest Ethiopia
Conclusions The prediction model was developed from eight easy-to-collect predictors. The model has excellent discrimination and calibration performance, similar to that of the risk score model. It is simple, easily remembered, and helps clinicians identify the risk of patients and manage it properly. Prospective studies in different healthcare settings are required to externally validate our risk score.
Source: BMJ Open - March 28, 2023 Category: General Medicine Authors: Abebe, T. G., Feleke, S. F., Dessie, A. M., Anteneh, R. M., Anteneh, Z. A. Tags: Open access, Cardiovascular medicine Source Type: research

Rationale and design of Short-Term EXenatide therapy in Acute ischaemic Stroke (STEXAS): a randomised, open-label, parallel-group study
Conclusions As GLP-1 analogues require elevated glucose levels to exert their insulin potentiating activity, the use of exenatide in the management of hyperglycaemia in AIS may reduce the incidence of hypoglycaemia, thereby conferring a benefit in morbidity and mortality for patients in the long term. Trial registration number ACTRN12614001189617.
Source: BMJ Open - February 24, 2016 Category: Journals (General) Authors: McGrath, R. T., Hocking, S. L., Priglinger, M., Day, S., Herkes, G. K., Krause, M., Fulcher, G. R. Tags: Open access, Neurology, Research methods, Diabetes and Endocrinology Protocol Source Type: research

Incidence of stroke, systemic embolism and bleeding events in patients without anticoagulation based on real-world data in Japan: a retrospective cohort study
Conclusions Approximately one-third of the patients do not receive any anticoagulation in the modern DOAC era in Japan. The SSE rate increases by the CHADS2 score. The SSE rate is low in patients with a CHADS2 score <1, supporting no indication of anticoagulation in current guidelines. In patients with a CHADS2 score >1, the use of anticoagulant drug therapy is recommended because of a higher risk of stroke.
Source: BMJ Open - November 10, 2022 Category: General Medicine Authors: Tanizawa, K., Nishimura, Y., Sera, S., Yaguchi, D., Okada, A., Nishikawa, M., Tamaru, S., Nagai, N. Tags: Open access, Epidemiology Source Type: research

Service factors causing delay in specialist assessment for TIA and minor stroke: a qualitative study of GP and patient perspectives
Conclusions Primary and emergency care providers need to review how they can best handle patients presenting with symptoms that could be due to stroke or TIA. In general practice, this may include receptionist training and/or triage by a nurse or doctor. Mechanisms need to be established to enable direct referral to the TIA clinic when patients whose symptoms have resolved present to other agencies. Further work is needed to improve diagnostic accuracy by non-specialists.
Source: BMJ Open - May 16, 2016 Category: Journals (General) Authors: Wilson, A., Coleby, D., Regen, E., Phelps, K., Windridge, K., Willars, J., Robinson, T. Tags: Open access, Cardiovascular medicine, Emergency medicine, Health services research, Qualitative research Source Type: research

Predictors of mortality in acute ischemic stroke treated with endovascular thrombectomy despite successful reperfusion: subgroup analysis of a multicentre randomised clinical trial
Conclusions Symptomatic ICH and high post-thrombectomy NIHSS score are strong predictor of 90-day mortality in acute ischaemic stroke treated with mechanical thrombectomy despite successful reperfusion, as well as high NIHSS score and high glucose level at hospital arrival. However, further studies need to be performed to confirm the association between smoking and mortality.
Source: BMJ Open - March 1, 2022 Category: General Medicine Authors: Li, H., Huang, J., Ye, S., Chen, H., Yuan, L., Liao, G., Du, W., Li, C., Fang, L., Liu, S., Yang, P., Zhang, Y., Xing, P., Zhang, X., Ye, X., Peng, Y., Cao, J., Zhang, L., Yang, Z., Liu, J., on behalf of the DIRECT-MT investigators, Yang, Zhang, Zhang, Zh Tags: Open access, Neurology Source Type: research