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Isolated Unilateral Ptosis due to Paramedian Midbrain Infarction
A 59-year-old man who had hypertension, dyslipidemia, diabetes mellitus, and left eye glaucoma developed sudden vertigo and left ptosis; he did not notice diplopia. He visited our hospital on day 3 after onset and neurologic examination showed left ptosis. His left visual acuity was counting fingers, and the light reflex was sluggish owing to glaucoma. Pupil sizes were equal, and eye movements and the lower lid were unremarkable. Magnetic resonance images revealed an acute infarction of the left paramedian midbrain.
Source: Journal of Stroke and Cerebrovascular Diseases - March 25, 2015 Category: Neurology Authors: Eriko Sugawara, Haruko Nakamura, Masanao Endo, Fumiaki Tanaka, Tatsuya Takahashi Tags: Case Report Source Type: research

Complete Oculomotor Nerve Palsy Caused by Direct Compression of the Posterior Cerebral Artery
Oculomotor nerve palsy frequently occurs because of external compression by an internal carotid-posterior communicating artery aneurysm and diabetes mellitus. In addition, pontine infarction, cavernous sinus tumors, demyelinating disease, and autoimmune disorder are well-known causes of oculomotor nerve palsy. However, cases of complete oculomotor nerve palsy by neurovascular conflicts presented with a sudden onset of clinical symptoms are extremely rare. We experienced a rare case of complete oculomotor nerve palsy because of direct vascular compression of the oculomotor nerve by the posterior cerebral artery.
Source: Journal of Stroke and Cerebrovascular Diseases - May 1, 2015 Category: Neurology Authors: Yoon-Sik Jo, Shin Kyoung Kim, Dae Ho Kim, Jae-Hwan Kim, Sang-Jun Na Tags: Case Report Source Type: research

Influence of Diabetes Mellitus and Cigarette Smoking on Variability of the Clopidogrel-Induced Antiplatelet Effect and Efficacy of Active Management of the Target P2Y12 Reaction Unit Range in Patients Undergoing Neurointerventional Procedures
Optimal antiplatelet inhibition is essential in patients undergoing neurointerventional procedures; however, variability in response to clopidogrel can contribute to thromboembolic and hemorrhagic complications. The present study evaluated the influence of diabetes mellitus and cigarette smoking on clopidogrel reactivity.
Source: Journal of Stroke and Cerebrovascular Diseases - October 19, 2015 Category: Neurology Authors: Ichiro Nakagawa, Hun Soo Park, Shohei Yokoyama, Takeshi Wada, Yasuo Hironaka, Yasushi Motoyama, Katsutoshi Takayama, Kimihiko Kichikawa, Hiroyuki Nakase Source Type: research

Prospective Association between Diabetic Retinopathy and Cardiovascular Disease—A Systematic Review and Meta-analysis of Cohort Studies
In this study, we performed a systematic review and meta-analysis of available cohort studies to determine the association between DR and CV disease, and to investigate the factors that influence the association.
Source: Journal of Stroke and Cerebrovascular Diseases - April 7, 2016 Category: Neurology Authors: Vivian Yawei Guo, Bing Cao, Xinyin Wu, Jack Jock Wai Lee, Benny Chung-ying Zee Source Type: research

Prospective Association between Diabetic Retinopathy and Cardiovascular Disease —A Systematic Review and Meta-analysis of Cohort Studies
In this study, we performed a systematic review and meta-analysis of available cohort studies to determine the association between DR and CV disease, and to investigate the factors that influence the association.
Source: Journal of Stroke and Cerebrovascular Diseases - April 7, 2016 Category: Neurology Authors: Vivian Yawei Guo, Bing Cao, Xinyin Wu, Jack Jock Wai Lee, Benny Chung-ying Zee Source Type: research

Diabetes Mellitus with Chronic Complications in Relation to Carotid Endarterectomy and Carotid Artery Stenting Outcomes
Carotid endarterectomy and carotid artery stenting are effective treatment procedures for carotid artery stenosis. Although diabetes mellitus is highly prevalent among patients undergoing these revascularization procedures, few studies have examined their impact on periprocedural outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - October 30, 2016 Category: Neurology Authors: Oluwole Adegbala, Kimberly D. Martin, David Otuada, Tomi Akinyemiju Source Type: research

Clinical Outcome Predicted by Collaterals Depends on Technical Success of Mechanical Thrombectomy in Middle Cerebral Artery Occlusion
This study aimed to analyze the effects of technical outcome of mechanical thrombectomy (MTE) on the associations between collateral status, assessed with pretreatment computed tomography angiography (CTA), and neurological and functional outcome, as well as associations between collaterals and metabolic risk factors (arterial hypertension, diabetes, hyperlipidemia, overweight).
Source: Journal of Stroke and Cerebrovascular Diseases - November 13, 2016 Category: Neurology Authors: Alexandra S. Gersing, Benedikt J. Schwaiger, Justus F. Kleine, Johannes Kaesmacher, Silke Wunderlich, Benjamin Friedrich, Sascha Prothmann, Claus Zimmer, Tobias Boeckh-Behrens Source Type: research

Assessment of Carotid Plaque Inflammation in Diabetic and Nondiabetic Patients —An Exploratory Ultrasmall Superparamagnetic Iron Oxide-Enhanced Magnetic Resonance Imaging Study
Ultrasmall superparamagnetic iron oxide (USPIO)-enhanced magnetic resonance (MR) imaging enables the identification of inflammation within the atheroma, predominantly by USPIO uptake by macrophages present in atherosclerotic tissue. Diabetic patients, however, may have dysfunctional macrophage activity, which may affect utilization of USPIO in identifying plaque inflammation in this patient cohort.
Source: Journal of Stroke and Cerebrovascular Diseases - November 20, 2016 Category: Neurology Authors: Ammara Usman, Andrew J. Patterson, Umar Sadat, Tjun Y. Tang, Martin J. Graves, Jonathan H. Gillard Source Type: research

The Relationship between Neutrophil-to-Lymphocyte Ratio and Intracerebral Hemorrhage in Type 2 Diabetes Mellitus
This study aimed to explore the relation between NLR and cerebral hemorrhage, and to prove that NLR is an independent risk factor of cerebral hemorrhage in T2DM patients.
Source: Journal of Stroke and Cerebrovascular Diseases - November 27, 2016 Category: Neurology Authors: Peng Luo, Rui Li, Siyuan Yu, Tingting Xu, Shufan Yue, Yongli Ji, Xin Chen, Haiting Xie Source Type: research

Repeated Paradoxical Brain Infarctions in a Patient on Self-Managed Home Hemodialysis Using a Long-Term Indwelling Catheter
We describe the case of a 51-year-old Japanese man with an end-stage kidney disease caused by a 30-year history of type 1 diabetes mellitus. The patient had suffered repeated bilateral multiple brain infarctions within a short period of time after the initiation of a self-managed daily home hemodialysis regimen using a long-term indwelling catheter inserted into the right atrium. Despite extensive examinations, we could not find any embolic causes except for the catheter and a patent foramen ovale (PFO).
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2017 Category: Neurology Authors: Takuya Kiyohara, Tadataka Mizoguchi, Junya Kuroda, Yoshinobu Wakisaka, Aya Irie, Chie Kitaoka, Kiichiro Fujisaki, Udai Nakamura, Kazuhiko Tsuruya, Takanari Kitazono, Tetsuro Ago Tags: Case Studies Source Type: research

Multiple Lacunar Infarcts in Paroxysmal Nocturnal Hemoglobinuria
We report a case of a 49-year-old woman who has a medical history of diabetes mellitus, hypertension, and PNH and presented multiple lacunar strokes in a routine consultation with a hematologist.
Source: Journal of Stroke and Cerebrovascular Diseases - August 3, 2017 Category: Neurology Authors: Alex Tiburtino Meira, Gabriel Sampaio Froehner, Andr é Petean Trindade, Silméia Garcia Zanati Bazan, Gabriel Pereira Braga, Rodrigo Bazan Tags: Case Studies Source Type: research

Recently Uncontrolled Glycemia in Diabetic Patients Is Associated with the Severity of Intracranial Atherosclerosis
Diabetes mellitus is a specific risk factor for intracranial atherosclerosis (ICAS) regardless of race. However, it is largely unknown whether poor glycemic control is associated with the severity of ICAS in diabetic patients.
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2017 Category: Neurology Authors: Nari Choi, Jeong-Yoon Lee, Jun-Sang Sunwoo, Hakjae Roh, Moo-Young Ahn, Sung-Tae Park, Kyung Bok Lee Source Type: research

Late Transient Contrast-Induced Encephalopathy after Percutaneous Coronary Intervention
Cerebrovascular events are a recognized complication of cardiac catheterization, with various neurological symptoms. The incidence is estimated to be .3%-.4%.1 A much more infrequent complication is a contrast-induced encephalopathy (CIE) described about 50 cases in the literature. The pathogenesis is believed to be a direct neurotoxic effect causing an osmotic disruption of the blood –brain barrier.2,3 Risk factors are hypertension, diabetes mellitus, renal impairment, large volumes of contrast, and previous adverse reaction to iodinated contrast.
Source: Journal of Stroke and Cerebrovascular Diseases - February 3, 2018 Category: Neurology Authors: Andreas Eleftheriou, Avan Sabir Rashid, Fredrik Lundin Tags: Case Studies Source Type: research

Prognosis of Intracerebral Hemorrhage with Newly Diagnosed Diabetes Mellitus According to Hemoglobin A1c Criteria
Hemoglobin A1c (HbA1c) has been recommended for diagnosing diabetes mellitus (DM). We aimed to assess the prevalence of newly diagnosed diabetes mellitus (NDDM) in patients with intracerebral hemorrhage (ICH) using HbA1c criteria and to investigate the long-term prognosis of patients with ICH with NDDM.
Source: Journal of Stroke and Cerebrovascular Diseases - February 19, 2018 Category: Neurology Authors: Xinmiao Zhang, Jing Jing, Huaguang Zheng, Qian Jia, Xingquan Zhao, Liping Liu, Chunxue Wang, Xia Meng, Yuesong Pan, Yilong Wang, Yongjun Wang, Investigators for ACROSS-China Source Type: research

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