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Causal relationship between Alzheimer's disease and cardiovascular disease: a bidirectional Mendelian randomization analysis
This study applied a two-sample bidirectional Mendelian randomization method to explore the causal relationship between CVD and AD. Genome-wide association study (GWAS) data from 46 datasets of European populations (21,982 cases of AD and 41,944 controls) were utilized to obtain genetic instrumental variables for AD. In addition, genetic instrumental variables for atrial fibrillation (AF), heart failure (HF), myocardial infarction (MI), coronary heart disease (CHD), angina pectoris (AP), and ischemic stroke (IS) (including large-artery atherosclerotic stroke [LAS] and cardioembolic stroke [CES]) were selected from GWAS dat...
Source: Aging - September 4, 2023 Category: Biomedical Science Authors: Fengjun Zhang Dexian Xian Junchen Feng Luning Ning Tianshou Jiang Wenchang Xu Yuan Liu Qiong Zhao Min Peng Source Type: research

Clinical characteristics and predictors for in-hospital mortality in adult COVID-19 patients: A retrospective single center cohort study in Vilnius, Lithuania
ConclusionsAge, congestive heart failure, obesity, COPD, prior stroke, and increased concentration of urea, LDH, CRP, IL-6, troponin I, ALT to AST ratio were identified to be the predictors for in-hospital mortality of COVID-19 patients.
Source: PLoS One - August 25, 2023 Category: Biomedical Science Authors: Ieva Kubiliute Source Type: research

Korean vs. Western Exercise Capacity Nomograms for Korean Patients With Cardiovascular Disease
CONCLUSION: Korean patients with CVD with lower exercise capacity have higher risk of MACE. Considering inter-ethnic differences in cardiorespiratory fitness, the Korean nomogram provides more suitable reference values than the Western nomogram to determine lower exercise capacity and predict cardiovascular events in Korean patients with CVD.PMID:37309698 | PMC:PMC10261710 | DOI:10.3346/jkms.2023.38.e179
Source: Journal of Korean Medical Science - June 13, 2023 Category: Biomedical Science Authors: Soohyung Park Byambakhand Battumur Seo Yeon Yoon Yohan Lee Se Hyun Park Kyuho Lee Seungmin Back Jieun Lee Dong Oh Kang Jah Yeon Choi Seung-Young Roh Jin Oh Na Cheol Ung Choi Jin Won Kim Seung-Woon Rha Chang Gyu Park Eung Ju Kim Source Type: research

Gender Difference of Blood Pressure Control Rate and Clinical Prognosis in Patients With Resistant Hypertension: Real-World Observation Study
CONCLUSION: In resistant hypertension, men were younger than women, but end-organ damage was more common and the risk of cardiovascular event was higher. More intensive cardiovascular prevention strategies may be required in male patients with resistant hypertension.PMID:37096308 | PMC:PMC10125792 | DOI:10.3346/jkms.2023.38.e124
Source: Journal of Korean Medical Science - April 25, 2023 Category: Biomedical Science Authors: Hyung Joon Joo Yunjin Yum Yong Hyun Kim Jung-Woo Son Sung Hea Kim Seonghoon Choi Seongwoo Han Mi-Seung Shin Jin-Ok Jeong Eung Ju Kim Working Group on Hypertension Complication Source Type: research

Causes of death of patients with non-valvular atrial fibrillation in Asians
ConclusionDeath due to ischemic stroke was responsible for only 4.7% of all deaths in Asian AF patients. Non-CV death, such as infection/sepsis or malignancy, was more far more prevalent than CV death in Asian AF patients. An improved integrated care approach is needed to reduce the prevalence of non-CV death in Asian AF patients.
Source: PLoS One - March 1, 2023 Category: Biomedical Science Authors: Rungroj Krittayaphong Source Type: research

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