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Condition: Stroke

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Total 220238 results found since Jan 2013.

Blood Biomarkers for the Early Diagnosis of Stroke Clinical Sciences
Conclusions—The studied biomarkers were not sufficient for an accurate differential diagnosis of stroke in the hyperacute setting. Additional discovery of new biomarkers and improvement on laboratory techniques seem necessary for achieving a molecular diagnosis of stroke.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Aleȷandro Bustamante, Elena Lopez–Cancio, Sara Pich, Anna Penalba, Dolors Giralt, Teresa Garcia–Berrocoso, Carles Ferrer–Costa, Teresa Gasull, Maria Hernandez–Perez, Monica Millan, Marta Rubiera, Pedro Cardona, Luis Cano, He Tags: Biomarkers, Clinical Studies, Diagnostic Testing, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

The Nottingham Fatigue After Stroke (NotFAST) study: results from follow-up six months after stroke.
Conclusions Half the stroke survivors reported fatigue at six months post-stroke. Reduced independence in activities of daily living and higher anxiety levels were associated with the level of fatigue. Persistent and delayed onset fatigue may affect independence and participation in rehabilitation, and these findings should be used to inform the development of appropriate interventions. PMID: 28891760 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - September 11, 2017 Category: Neurology Authors: Hawkins L, Lincoln NB, Sprigg N, Ward NS, Mistri A, Tyrrell P, Worthington E, Drummond A Tags: Top Stroke Rehabil Source Type: research

Sodium Valproate, a Histone Deacetylase Inhibitor, Is Associated With Reduced Stroke Risk After Previous Ischemic Stroke or Transient Ischemic Attack Clinical Sciences
Conclusions—These results suggest that exposure to SVA, an inhibitor of HDAC, may be associated with a lower recurrent stroke risk although we cannot exclude residual confounding in this study design. This supports the hypothesis that HDAC9 is important in the ischemic stroke pathogenesis and that its inhibition, by SVA or a more specific HDAC9 inhibitor, is worthy of evaluation as a treatment to prevent recurrent ischemic stroke.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Rebecca L. Brookes, Siobhan Crichton, Charles D.A. Wolfe, Qilong Yi, Linxin Li, Graeme J. Hankey, Peter M. Rothwell, Hugh S. Markus Tags: Secondary Prevention, Genetics, Ischemic Stroke, Atherosclerosis Original Contributions Source Type: research

Stroke Incidence and Outcomes in Northeastern Greece Clinical Sciences
Conclusions—This is the largest to date population-based study in Greece documenting one of the highest stroke incidences ever reported in South Europe, highlighting the need for efficient stroke prevention and treatment strategies in Northeastern Greece.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Georgios Tsivgoulis, Athanasia Patousi, Maria Pikilidou, Theodosis Birbilis, Aristeidis H. Katsanos, Michalis Mantatzis, Aristeidis Asimis, Nikolaos Papanas, Panagiotis Skendros, Aikaterini Terzoudi, Aikaterini Karamanli, Ioannis Kouroumichakis, Pantelis Tags: Epidemiology, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Polygenic Risk for Depression Increases Risk of Ischemic Stroke Clinical Sciences
Conclusions—Higher polygenic risk for major depressive disorder is associated with increased risk of ischemic stroke overall and with small artery occlusion. Additional associations with ischemic stroke subtypes differed by ancestry.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Sylvia Wassertheil-Smoller, Qibin Qi, Tushar Dave, Braxton D. Mitchell, Rebecca D. Jackson, Simin Liu, Ki Park, Joel Salinas, Erin C. Dunn, Enrique C. Leira, Huichun Xu, Kathleen Ryan, Jordan W. Smoller Tags: Etiology, Mental Health, Genetic, Association Studies, Ischemic Stroke Original Contributions Source Type: research

Predictors of Thrombolysis Administration in Mild Stroke Clinical Sciences
Conclusions—Mild acutely presenting stroke patients are more likely to receive thrombolysis if they are young, white, or Hispanic and arrive early to the hospital with more severe neurological presentation. Identification of predictors of thrombolysis is important in design of future studies to assess the use of thrombolysis for mild stroke.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Negar Asdaghi, Kefeng Wang, Maria A. Ciliberti-Vargas, Carolina Marinovic Gutierrez, Sebastian Koch, Hannah Gardener, Chuanhui Dong, David Z. Rose, Enid J. Garcia, W. Scott Burgin, Juan Carlos Zevallos, Tatjana Rundek, Ralph L. Sacco, Jose G. Romano Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Role of Blood Lipids in the Development of Ischemic Stroke and its Subtypes Clinical Sciences
Conclusions—LDL cholesterol lowering is likely to prevent large artery atherosclerosis but may not prevent small artery occlusion nor cardioembolic strokes. High-density lipoprotein cholesterol elevation may lead to benefits in small artery disease prevention. Finally, triglyceride lowering may not yield benefits in ischemic stroke and its subtypes.
Source: Stroke - March 26, 2018 Category: Neurology Authors: George Hindy, Gunnar Engstrom, Susanna C. Larsson, Matthew Traylor, Hugh S. Markus, Olle Melander, Marȷu Orho–Melander Tags: Lipids and Cholesterol, Risk Factors, Ischemic Stroke Original Contributions Source Type: research

Trajectories of positive aspects of caregiving among family caregivers of stroke-survivors: the differential impact of stroke-survivor disability.
Conclusions Care professionals should be mindful of the heterogeneity in the longitudinal pattern of positive feelings resulting from care provision among family caregivers of stroke-survivors, and the differential impact of stroke-survivor disability on the pattern of positive feelings. Younger caregivers as well as family caregivers who have low positive feelings at the start of their caregiver journey and experience worsening functional disability of their care recipient (stroke-survivor) require greater attention and support. PMID: 29577825 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - March 26, 2018 Category: Neurology Authors: Malhotra R, Chei CL, Menon EB, Chow WL, Quah S, Chan A, Ajay S, Matchar DB Tags: Top Stroke Rehabil Source Type: research

Frequency of Patent Foramen Ovale and Migraine in Patients With Cryptogenic Stroke Clinical Sciences
Conclusions—In patients with cryptogenic stroke who have migraine, there is a high prevalence (79%) of PFO with right-to-left shunt. The timing of the stroke in migraineurs is usually not related to a migraine attack. These observations are consistent with the hypothesis that the mechanism of stroke in migraineurs is most likely because of a paradoxical embolus. Future cryptogenic stroke classification schemes should consider including PFO as a separate etiologic category.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Brian H. West, Nabil Noureddin, Yakov Mamzhi, Christopher G. Low, Alexandra C. Coluzzi, Evan J. Shih, Rubine Gevorgyan Fleming, Jeffrey L. Saver, David S. Liebeskind, Andrew Charles, Jonathan M. Tobis Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Embolism Original Contributions Source Type: research

Factors affecting rehabilitation and use of upper limb after stroke: views from healthcare professionals and stroke survivors.
CONCLUSION: The findings indicate that stroke survivors and healthcare professionals have very similar understandings of barriers to UL activity, and positive upper limb rehabilitation behaviors are not always established early in recovery post-stroke. Increased resources and healthcare professional-patient relationships seem key factors to establishing positive perceptions of UL rehabilitation. Addressing psychosocial issues and resource limitations may help sustain engagement with UL rehabilitation. PMID: 30422096 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - November 13, 2018 Category: Neurology Authors: Meadmore KL, Hallewell E, Freeman C, Hughes AM Tags: Top Stroke Rehabil Source Type: research

Assessment of backward walking unmasks mobility impairments in post-stroke community ambulators.
CONCLUSIONS: Assessment of BW can unmask post-stroke walking impairments not detected during typical FW. BW impairments may contribute to the mobility difficulties reported by adults post-stroke. Therefore, BW should be assessed when determining readiness for home and community ambulation. PMID: 31081491 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - May 11, 2019 Category: Neurology Authors: Hawkins KA, Balasubramanian CK, Vistamehr A, Conroy C, Rose DK, Clark DJ, Fox EJ Tags: Top Stroke Rehabil Source Type: research

Muscle changes after stroke and their impact on recovery: time for a paradigm shift? Review and commentary.
Abstract In stroke rehabilitation there is a growing body of evidence that not all patients have the same potential to recover. Understanding the processes that give rise to the heterogeneous treatment responses in stroke survivors will lay foundations for any conceivable advance in future rehabilitation interventions. This review was set out to shine new light on the debate of biomarkers in stroke rehabilitation by linking fundamental insights from biogerontological sciences to neurorehabilitation sciences. In particular, skeletal muscle changes and inflammation are addressed as two potential constructs from whic...
Source: Topics in Stroke Rehabilitation - June 25, 2020 Category: Neurology Authors: Beckwée D, Lefeber N, Bautmans I, Cuypers L, De Keersmaecker E, De Raedt S, Kerckhofs E, Nagels G, Njemini R, Perkisas S, Scheys E, Swinnen E Tags: Top Stroke Rehabil Source Type: research

Adiposity, Adipokines, and Risk of Incident Stroke in Older Men Original Contributions
Conclusions— Conventional adiposity measures were not associated with increased stroke risk in older men. However, leptin (a good marker of percent fat mass), but not adiponectin, predicted stroke, suggesting a link between fat mass and stroke risk.
Source: Stroke - December 24, 2012 Category: Neurology Authors: Wannamethee, S. G., Shaper, A. G., Whincup, P. H., Lennon, L., Sattar, N. Tags: Acute Cerebral Infarction, Risk Factors for Stroke, Epidemiology Original Contributions Source Type: research

Acute Cerebrovascular Disease in the Young: The Stroke in Young Fabry Patients Study Original Contributions
Conclusions— Definite Fabry disease occurs in 0.5% and probable Fabry disease in further 0.4% of young stroke patients. Silent infarcts, white matter intensities, and classical risk factors were highly prevalent, emphasizing the need for new early preventive strategies. Clinical Trial Registration Information— URL: http://www.clinicaltrials.gov.Unique identifier: NCT00414583
Source: Stroke - January 18, 2013 Category: Neurology Authors: Rolfs, A., Fazekas, F., Grittner, U., Dichgans, M., Martus, P., Holzhausen, M., Bottcher, T., Heuschmann, P. U., Tatlisumak, T., Tanislav, C., Jungehulsing, G. J., Giese, A.-K., Putaala, J., Huber, R., Bodechtel, U., Lichy, C., Enzinger, C., Schmidt, R., Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Acute Stroke Syndromes, Genetics of Stroke Original Contributions Source Type: research

Trends and Survival Between Ethnic Groups After Stroke: The South London Stroke Register Original Contributions
Conclusions— Survival has improved in a multiethnic population over time. The independent survival advantage of black Caribbean and black African over White group in those aged over 65 may be a healthy migrant effect of first generation migrants. The increase in admission to a stroke unit may contribute to the improvement in survival after stroke.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Wang, Y., Rudd, A. G., Wolfe, C. D. A. Tags: Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Risk Factors for Stroke, Epidemiology Original Contributions Source Type: research