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Potential role of Nigella Sativa and its Constituent (Thymoquinone) in Ischemic Stroke
Curr Mol Med. 2023 Apr 10. doi: 10.2174/1566524023666230410101724. Online ahead of print.ABSTRACTIschemic stroke is one of the major causes of global mortality, which puts great demands on health systems and social welfare. Ischemic stroke is a complex pathological process involving a series of mechanisms such as ROS accumulation, Ca2 + overload, inflammation, and apoptosis. The lack of effective and widely applicable pharmacological treatments for ischemic stroke patients has led scientists to find new treatments. The use of herbal medicine, as an alternative or complementary therapy, is increasing worldwide. For centurie...
Source: Current Molecular Medicine - April 11, 2023 Category: Molecular Biology Authors: Shakiba Azami Fatemeh Forouzanfar Source Type: research

Alternative medicine therapies in neurological disorders: Prevalence, reasons and associated factors. A systematic review
CONCLUSIONS: The prevalence of CAM use in neurological diseases is highly variable (16%-100%); the most used type of CAM was biological therapies and the associated factors were female sex, age between 40 and 50 years old and high socioeconomic level.PMID:36805318 | DOI:10.1016/j.ctim.2023.102932
Source: Complementary Therapies in Medicine - February 22, 2023 Category: Complementary Medicine Authors: Mar ía Soto-Lara Melissa Silva-Loredo Jos é Rodrigo Monroy-Córdoba Paola Flores-Ordo ñez Nelly G Cervera-Delgadillo Paul Carrillo-Mora Source Type: research

Mechanism of < em > Salvia miltiorrhiza Bge < /em > . for the Treatment of Ischemic Stroke Based on Bioinformatics and Network Pharmacology
In this study, SymMap was used to screen the 50 bioactive scored components and 65 putative targets of Salvia miltiorrhiza Bge., and their targets were standardized using the UniProt platform. The disease targets related to stroke were collected by comparative toxicogenomics database (CTD), GeneCards, and quantitative structure-activity relationships-TargetNet (QSAR-TargetNet). Thereafter, the protein-protein interaction (PPI) network was constructed using the STRING platform and visualized by Cytoscape (3.8.2) software. Then, the Metascape platform was used to analyze the Gene Ontology (GO) enrichment analysis and Kyoto E...
Source: Evidence-based Complementary and Alternative Medicine - September 22, 2022 Category: Complementary Medicine Authors: Jiaqi Wu Ming Li Ang Li Xunming Ji Source Type: research

Anti-Diabesity Middle Eastern Medicinal Plants and Their Action Mechanisms
Evid Based Complement Alternat Med. 2022 Jul 18;2022:2276094. doi: 10.1155/2022/2276094. eCollection 2022.ABSTRACTOver the last four decades, the escalation in diabetes and obesity rates has become epidemic all over the world. Diabesity describes the strong link between T2D and obesity. It correlates deeper with the elevated risks of developing cardiovascular disease hypertension, stroke, and several malignancies. Therapeutic usage of medicinal plants and natural products in the treatment of diabetes and obesity has long been known to physicians of Greco-Arab and Islamic medicine. Improved versions of their abundant medici...
Source: Evidence-based Complementary and Alternative Medicine - July 28, 2022 Category: Complementary Medicine Authors: Bashar Saad Abdalsalam Kmail Sameena Z H Haq Source Type: research

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