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Acrolein: formation, health hazards and its controlling by dietary polyphenols
Crit Rev Food Sci Nutr. 2023 May 19:1-14. doi: 10.1080/10408398.2023.2214625. Online ahead of print.ABSTRACTAcrolein, a highly reactive toxic aldehyde, is a common dietary and environmental contaminant which can also be generated endogenously. Exposure to acrolein has been positively associated with some pathological conditions, such as atherosclerosis, diabetes mellitus, stroke, and Alzheimer's disease. At the cellular level, acrolein induces various harmful effects, particularly protein adduction and oxidative damages. Polyphenols are a group of secondary plant metabolites ubiquitously presented in fruits, vegetables, an...
Source: Atherosclerosis - May 19, 2023 Category: Cardiology Authors: Yue Zhou Wendy Jin Qingli Wu Qian Zhou Source Type: research

Bioactive Compounds (BACs): A Novel Approach to Treat and Prevent Cardiovascular Diseases
Curr Probl Cardiol. 2023 Feb 23:101664. doi: 10.1016/j.cpcardiol.2023.101664. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs) are one of the leading disorders of serious death and cause huge economic loss to patients and society. It is estimated that about 18 million people have a high death ratio due to the incidence of CVDs such as (stroke, coronary heart disease, and non-ischemic heart failure). Bioactive compounds (BACs) are healthy nutritional ingredients providing beneficial effects and nutritional value to the human body. Epidemiological studies strongly shed light on several bioactive compounds that ar...
Source: Atherosclerosis - February 25, 2023 Category: Cardiology Authors: Syed Riaz Ud Din Sumbul Saeed Shahid Ullah Khan Mintao Zhong Source Type: research

Pharmacological and Molecular Insight on the Cardioprotective Role of Apigenin
Nutrients. 2023 Jan 12;15(2):385. doi: 10.3390/nu15020385.ABSTRACTApigenin is a naturally occurring dietary flavonoid found abundantly in fruits and vegetables. It possesses a wide range of biological properties that exert antioxidant, anti-inflammatory, anticancer, and antibacterial effects. These effects have been reported to be beneficial in the treatment of atherosclerosis, stroke, hypertension, ischemia/reperfusion-induced myocardial injury, and diabetic cardiomyopathy, and provide protection against drug-induced cardiotoxicity. These potential therapeutic effects advocate the exploration of the cardioprotective actio...
Source: Atherosclerosis - January 21, 2023 Category: Cardiology Authors: Shilu Deepa Thomas Niraj Kumar Jha Saurabh Kumar Jha Bassem Sadek Shreesh Ojha Source Type: research

Hawthorn fruit acid consumption attenuates hyperlipidemia-associated oxidative damage in rats
CONCLUSION: HFA administration can provide health benefits by counteracting the effects of hyperlipidemia caused by an HFD in the body, and the underlying mechanism of this event is closely related to the activation of the Nrf2/HO-1 signaling pathway.PMID:35990322 | PMC:PMC9384962 | DOI:10.3389/fnut.2022.936229
Source: Atherosclerosis - August 22, 2022 Category: Cardiology Authors: Yicheng Feng Shan Gao Ting Zhu Guibo Sun Peisen Zhang Yichun Huang Shuang Qu Xiaomeng Du Dehua Mou Source Type: research

Promising Nutritional Fruits Against Cardiovascular Diseases: An Overview of Experimental Evidence and Understanding Their Mechanisms of Action
Vasc Health Risk Manag. 2021 Nov 23;17:739-769. doi: 10.2147/VHRM.S328096. eCollection 2021.ABSTRACTCardiovascular diseases (CVDs) are one of the leading causes of morbidity and mortality in both developed and developing countries, affecting millions of individuals each year. Despite the fact that successful therapeutic drugs for the management and treatment of CVDs are available on the market, nutritional fruits appear to offer the greatest benefits to the heart and have been proved to alleviate CVDs. Experimental studies have also demonstrated that nutritional fruits have potential protective effects against CVDs. The ai...
Source: Atherosclerosis - December 3, 2021 Category: Cardiology Authors: Nur Zulaikha Azwa Zuraini Mahendran Sekar Yuan Seng Wu Siew Hua Gan Srinivasa Reddy Bonam Nur Najihah Izzati Mat Rani M Yasmin Begum Pei Teng Lum Vetriselvan Subramaniyan Neeraj Kumar Fuloria Shivkanya Fuloria Source Type: research

Diet, microparticles and atherothrombosis.
Abstract Cardiovascular disease is the main cause of death worldwide, and is principally caused by atherosclerosis, with subsequent thrombus formation, eventually provoking an acute myocardial infarction or a stroke. The formation and progression of the atherosclerotic plaques responds to multiple factors including certain diets. Intensive research has elucidated the role of diet in cardiovascular disease and has led to public health policies focusing on educating the population on the role of nutrition in cardiovascular health. Compelling evidence shows that a healthy diet, rich in fruit and vegetables with moder...
Source: Atherosclerosis - September 22, 2017 Category: Cardiology Authors: Badimon L, Suades R, Crespo J, Padro T, Chiva-Blanch G Tags: Front Biosci (Landmark Ed) Source Type: research